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ACAD Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
22.180
Open
22.110
VWAP
21.89
Vol
991.72K
Mkt Cap
3.77B
Low
21.700
Amount
21.71M
EV/EBITDA(TTM)
25.28
Total Shares
170.49M
EV
2.95B
EV/OCF(TTM)
26.83
P/S(TTM)
3.50
Acadia Pharmaceuticals Inc. is a biopharmaceutical company. It develops and commercializes medicines that address unmet medical needs in central nervous system (CNS) disorders and rare diseases. It has a portfolio of product candidates and research programs that are designed to address significant unmet medical needs in CNS disorders and rare diseases. Its pipeline includes NUPLAZID (pimavanserin), DAYBUE (trofinetide), ACP-101, ACP-204, and ACP-711. NUPLAZID is a selective serotonin inverse agonist/antagonist preferentially targeting the 5-HT2A receptor. NUPLAZID is developed for the treatment for Parkinson's Disease Psychosis. Trofinetide is a novel synthetic analog of the amino-terminal tripeptide of insulin-like growth factor 1 designed to treat the core symptoms of Rett syndrome by reducing neuroinflammation and supporting synaptic function. Its early-stage research programs and product candidates include ACP-211, ACP-2591, ACP-271, and Antisense Oligonucleotide (ASO) Programs.
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Events Timeline

(ET)
2026-04-07
09:30:00
Acadia Pharmaceuticals Launches Daybue Stix for Rett Syndrome Treatment
select

News

Newsfilter
8.5
04-17Newsfilter
Acadia Pharmaceuticals to Present Multiple Data at AAN Annual Meeting
  • Data Presentation: Acadia Pharmaceuticals will present multiple original data sets at the 2026 American Academy of Neurology Annual Meeting, reflecting the company's ongoing commitment to research in neurological diseases.
  • LOTUS Study Findings: The company will share real-world data on DAYBUE® (trofinetide) in adults with Rett syndrome, highlighting its benefits and tolerability in clinical practice, which may enhance market acceptance of the drug.
  • Parkinson's Disease Psychosis Analysis: Acadia will also present exploratory analyses of NUPLAZID® (pimavanserin) treatment response trajectories in Parkinson's disease psychosis patients, revealing the impact of baseline sleep disturbances on treatment outcomes, potentially informing personalized treatment approaches.
  • ACP-711 Development Progress: The company will debut translational research and pharmacokinetic data for ACP-711, supporting its development for essential tremor, showcasing Acadia's forward-looking strategy in neurological drug development.
Newsfilter
8.5
04-07Newsfilter
Acadia Launches DAYBUE STIX Powder for Rett Syndrome Treatment
  • New Drug Launch: Acadia Pharmaceuticals announced that DAYBUE STIX (trofinetide) powder formulation is now broadly available in the U.S. for treating Rett syndrome in patients aged two and older, marking a significant innovation in the neurological disease sector.
  • High Patient Satisfaction: Initial feedback indicates that over 80% of early users reported satisfaction with DAYBUE STIX, highlighting its advantages in flexibility and portability, which may enhance the medication experience for patients.
  • Expert Consensus Support: A steering group of experts from the International Rett Syndrome Foundation has recognized trofinetide oral solution as part of the standard of care, emphasizing the importance of individualized decision-making to optimize treatment outcomes for patients and families, further solidifying DAYBUE STIX's clinical position.
  • Diverse Administration Options: DAYBUE STIX can be mixed with various water-based liquids, providing personalized taste options that cater to the unique needs of patients and caregivers, aligning with modern healthcare's patient-centered treatment philosophy.
seekingalpha
6.0
03-25seekingalpha
BofA Upgrades Acadia Pharmaceuticals to Buy Amid Price Pullback
  • Rating Upgrade: BofA Securities has upgraded Acadia Pharmaceuticals (ACAD) from neutral to buy, citing that the company's fundamentals remain intact despite a 25% pullback in share price since the beginning of the year, which is attributed mainly to macro factors.
  • Price Target Maintained: The bank maintains a price target of $29 for Acadia, which implies approximately 38% upside based on the March 24 close, reflecting confidence in the company's future performance.
  • Sales Forecast: Analysts project that steady sales of Nuplazid (pimavanserin) will help mitigate further downside risks, estimating peak sales of $888 million by 2029, indicating strong market potential for the product.
  • Pipeline Opportunity: While the company estimates its pipeline could offer an $11 billion opportunity, BofA believes this figure is currently discounted and may provide upside, reiterating a 40% likelihood of success for remlifanserin with projected peak sales of $2.1 billion in 2038.
CNBC
6.0
03-25CNBC
Latest Rating Changes on Wall Street
  • Tesla Neutral Rating: Goldman Sachs maintains a neutral stance on Tesla, expressing caution regarding its semiconductor ventures, noting a mixed track record in semiconductor engineering, while suggesting potential applications for inference chips in data centers and distributed computing remain to be seen.
  • Upgrade Based on Iran War: Wells Fargo upgrades Kinetik, ONEOK, and Enterprise Products Partners from equal weight to overweight, anticipating that the Iran war will create a structural shift in global energy markets, boosting demand for U.S. energy, particularly in Permian gas and NGL supply.
  • ESCO Technologies Buy Initiation: Deutsche Bank initiates coverage on ESCO Technologies with a Buy rating and a $350 target price, highlighting its potential for “defensive growth at a discount” in the aerospace and defense sectors, indicating strong confidence in the company's future.
  • Arm Rating Upgrade: Wolfe upgrades Arm from market perform to outperform, citing the company's recent in-house chip launch and significantly increased earnings forecasts for FY28 and FY31, setting a target price of $166, reflecting optimism about its new business model.
NASDAQ.COM
9.0
03-03NASDAQ.COM
Neuren and Acadia Request Re-examination for Rett Syndrome Drug
  • Re-examination Request: Acadia Pharmaceuticals will request a re-examination of the CHMP's opinion on trofinetide, aimed at treating Rett syndrome in patients aged two and older, reflecting ongoing commitment to drug approval efforts.
  • Market Authorization: Trofinetide is already approved in the U.S., Canada, and Israel, representing the first and only treatment for Rett syndrome, highlighting its potential and significance in the global market.
  • Executive Commentary: Acadia CEO Catherine Owen Adams expressed disappointment over the CHMP's refusal but remains optimistic about the drug's meaningful benefits for Rett syndrome patients, emphasizing positive feedback from patients and clinicians.
  • Market Reaction: ACAD shares fell 7.13% to $22.81 during regular trading on Monday, yet gained 0.04% in after-hours trading, indicating cautious optimism in the market regarding the drug's future potential.
stocktwits
9.0
02-28stocktwits
Aardvark Pauses PWS Trial, Shares Plunge 53%
  • Trial Pause Reason: Aardvark Therapeutics announced a voluntary pause of its ARD-101 trial for Prader-Willi Syndrome due to cardiac observations in a healthy volunteer study, with data release now expected to be delayed until Q3 2026, potentially impacting the company's future R&D trajectory.
  • Severe Market Reaction: Following the trial pause announcement, Aardvark's shares plunged 53% in after-hours trading, reflecting extreme investor concern over the company's outlook, which may lead to financing challenges and diminished market confidence.
  • Competitor Dynamics: In contrast, Soleno Therapeutics' VYKAT XR has become the first FDA-approved treatment for hyperphagia in Prader-Willi Syndrome, despite facing short-selling pressure and safety concerns from Scorpion Capital, highlighting the intense competition in the market.
  • Industry-Wide Challenges: Against the backdrop of Aardvark's trial pause, Acadia Pharmaceuticals also halted development of its intranasal Carbetocin, indicating that the challenges and risks associated with successful R&D in the Prader-Willi Syndrome treatment space are increasing, which could affect the overall investment attractiveness of the sector.
Wall Street analysts forecast ACAD stock price to rise
12 Analyst Rating
Wall Street analysts forecast ACAD stock price to rise
7 Buy
5 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
23.00
Averages
31.17
High
40.00
Current: 0.000
sliders
Low
23.00
Averages
31.17
High
40.00
RBC Capital
Outperform
maintain
$30 -> $29
AI Analysis
2026-04-07
Reason
RBC Capital
Price Target
$30 -> $29
AI Analysis
2026-04-07
maintain
Outperform
Reason
RBC Capital lowered the firm's price target on Acadia Pharmaceuticals to $29 from $30 and keeps an Outperform rating on the shares as part of the firm's broader research note previewing Q1 results in Biotech. Seasonal headwinds around gross/net, reimbursement resets, and fewer selling days may be exacerbated in Q1 by weather impact, particularly for launching and in-clinic products, but the robust return of M&A, coupled with clarity on limited tariff/Most Favored Nation drug pricing impacts, could help offset both this and broader macro volatility while keeping sector perceptions favorable, the analyst tells investors in a research note.
BofA
Tazeen Ahmad
Neutral -> Buy
upgrade
$29
2026-03-25
Reason
BofA
Tazeen Ahmad
Price Target
$29
2026-03-25
upgrade
Neutral -> Buy
Reason
As previously reported, BofA analyst Tazeen Ahmad upgraded Acadia Pharmaceuticals to Buy from Neutral with an unchanged price target of $29. The recent 25% pullback in share price is not related to fundamentals and more related to macro factors, says the analyst, who has no change to the firm's fundamental view of the company. The firm, which thinks stable Nuplazid sales in Parkinson's psychosis provides "protection against further downside," models $888M in 2029 peak sales, which it adds "could be conservative if recent field force investments accelerate growth." BofA also estimates an $11B pipeline opportunity, which it thinks is "currently discounted."
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for ACAD
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Valuation Metrics

The current forward P/E ratio for ACADIA Pharmaceuticals Inc (ACAD.O) is 51.02, compared to its 5-year average forward P/E of -1.35. For a more detailed relative valuation and DCF analysis to assess ACADIA Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-1.35
Current PE
51.02
Overvalued PE
81.63
Undervalued PE
-84.33

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
73.40
Current EV/EBITDA
39.33
Overvalued EV/EBITDA
380.61
Undervalued EV/EBITDA
-233.82

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
4.32
Current PS
2.71
Overvalued PS
5.78
Undervalued PS
2.85

Financials

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Whales Holding ACAD

B
Braidwell LP
Holding
ACAD
+12.09%
3M Return
L
Logos Global Management, L.P.
Holding
ACAD
+11.12%
3M Return
R
Rice Hall James & Associates, LLC
Holding
ACAD
+8.57%
3M Return
F
Frazier Life Sciences Management, LP
Holding
ACAD
+6.89%
3M Return
B
Baker Bros. Advisors LP
Holding
ACAD
+3.17%
3M Return
R
RTW Investments, LP
Holding
ACAD
+1.39%
3M Return

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Frequently Asked Questions

What is ACADIA Pharmaceuticals Inc (ACAD) stock price today?

The current price of ACAD is 21.8 USD — it has decreased -1.31

What is ACADIA Pharmaceuticals Inc (ACAD)'s business?

Acadia Pharmaceuticals Inc. is a biopharmaceutical company. It develops and commercializes medicines that address unmet medical needs in central nervous system (CNS) disorders and rare diseases. It has a portfolio of product candidates and research programs that are designed to address significant unmet medical needs in CNS disorders and rare diseases. Its pipeline includes NUPLAZID (pimavanserin), DAYBUE (trofinetide), ACP-101, ACP-204, and ACP-711. NUPLAZID is a selective serotonin inverse agonist/antagonist preferentially targeting the 5-HT2A receptor. NUPLAZID is developed for the treatment for Parkinson's Disease Psychosis. Trofinetide is a novel synthetic analog of the amino-terminal tripeptide of insulin-like growth factor 1 designed to treat the core symptoms of Rett syndrome by reducing neuroinflammation and supporting synaptic function. Its early-stage research programs and product candidates include ACP-211, ACP-2591, ACP-271, and Antisense Oligonucleotide (ASO) Programs.

What is the price predicton of ACAD Stock?

Wall Street analysts forecast ACAD stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ACAD is31.17 USD with a low forecast of 23.00 USD and a high forecast of 40.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is ACADIA Pharmaceuticals Inc (ACAD)'s revenue for the last quarter?

ACADIA Pharmaceuticals Inc revenue for the last quarter amounts to 283.99M USD, increased 9.39

What is ACADIA Pharmaceuticals Inc (ACAD)'s earnings per share (EPS) for the last quarter?

ACADIA Pharmaceuticals Inc. EPS for the last quarter amounts to 1.59 USD, increased 84.88

How many employees does ACADIA Pharmaceuticals Inc (ACAD). have?

ACADIA Pharmaceuticals Inc (ACAD) has 796 emplpoyees as of April 22 2026.

What is ACADIA Pharmaceuticals Inc (ACAD) market cap?

Today ACAD has the market capitalization of 3.77B USD.