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CRVO Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
4.070
Open
4.050
VWAP
3.92
Vol
56.64K
Mkt Cap
36.29M
Low
3.780
Amount
222.22K
EV/EBITDA(TTM)
--
Total Shares
9.26M
EV
16.36M
EV/OCF(TTM)
--
P/S(TTM)
9.07
CervoMed Inc. is a clinical-stage company focused on developing treatments for age-related neurologic disorders. The Company is developing neflamapimod, an investigational, orally administered small molecule brain penetrant that inhibits p38 mitogen-activated protein kinase alpha. Neflamapimod has the potential to treat synaptic dysfunction, the reversible aspect of the underlying neurodegenerative processes that cause disease in Lewy bodies (DLB) and certain other neurological disorders. It focuses on reducing the impact of inflammation in the brain, or neuroinflammation, which is a key factor in the manifestation of degenerative diseases of the brain, including DLB. Neflamapimod is being evaluated in the Company's ongoing RewinD-LB Trial, a Phase 2b trial in patients with DLB.
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Events Timeline

(ET)
2026-03-19
08:00:00
CervoMed Presents New Data on Neflamapimod at AD/PD 2026 Conference
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2026-03-17 (ET)
2026-03-17
07:50:00
CervoMed Expects Cash to Fund Operations for Six Months
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2026-03-12 (ET)
2026-03-12
07:30:00
CervoMed to Present Neflamapimod Research Progress at AD/PD 2026
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2026-03-04 (ET)
2026-03-04
07:40:00
CervoMed Completes Phase 1 Study of Neflamapimod
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2026-02-18 (ET)
2026-02-18
06:20:00
CervoMed's Oral Drug Neflamapimod Included in EXPERTS-ALS Platform
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2025-12-04 (ET)
2025-12-04
17:10:00
CervoMed Reports Positive Results from Alzheimer's Clinical Trial
select
2025-12-02 (ET)
2025-12-02
07:10:00
CervoMed Reports Significant Reduction in Neurodegeneration Biomarker from Phase 2b RewinD-LB Trial
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News

NASDAQ.COM
9.5
03-18NASDAQ.COM
CervoMed Reports 2025 Financial Results and Future Catalysts
  • Financial Performance: CervoMed reported a net loss of $27 million for the fiscal year 2025, a significant increase from a $16.2 million loss in 2024, indicating ongoing investment in R&D despite financial pressures.
  • Clinical Progress: The company made meaningful advancements in late 2025 and early 2026, particularly with positive Phase 2b RewinD-LB data in dementia with Lewy bodies, and has aligned with the FDA to initiate a Phase 3 trial in the second half of 2026.
  • Cash Position: As of the end of the reporting period, CervoMed had $20.9 million in cash and cash equivalents, expected to fund operations for approximately six months, highlighting potential funding challenges that may impact future R&D efforts.
  • Future Outlook: The company anticipates multiple clinical readouts in the second half of 2026, including topline data from two Phase 2a studies and the launch of a new ALS trial, demonstrating a proactive approach to capturing market opportunities and advancing its pipeline.
seekingalpha
9.5
03-17seekingalpha
CervoMed Reports $27M Net Loss for FY with Revenue Beat
  • Fiscal Year Loss: CervoMed reported a net loss of approximately $27 million for the fiscal year, indicating significant challenges in profitability that could impact investor confidence and future financing capabilities.
  • Revenue Performance: The company generated $4 million in revenue, a 58.9% year-over-year decline, although it beat expectations by $3.95 million, reflecting weak market demand that may necessitate strategic adjustments moving forward.
  • Earnings Warning: Given the ongoing losses and revenue decline, CervoMed may need to reassess its business model and market strategies to cope with pressures from industry competition and economic fluctuations.
  • Investor Attention: As the financial situation worsens, investors will closely monitor CervoMed's subsequent actions and management's response strategies to evaluate its long-term sustainability and potential for recovery.
Newsfilter
8.5
03-04Newsfilter
CervoMed Advances Neflamapimod in Phase 3 Trial for Dementia
  • Dose Selection: CervoMed has selected a dosing regimen of 50mg of neflamapimod three times daily for its planned Phase 3 trial to ensure plasma drug concentrations align with those of the clinically effective drug product, thereby enhancing therapeutic efficacy and patient response.
  • Manufacturing Process Improvement: The company has developed a new controlled manufacturing process that exclusively produces a stable crystal form of neflamapimod, addressing previous issues with multiple solid-state forms that led to decreased bioavailability, thus improving drug efficacy and safety.
  • Clinical Trial Results: In the Phase 2b RewinD-LB trial, neflamapimod demonstrated significant potential to improve cognitive and functional outcomes, particularly in patients without Alzheimer's disease co-pathology, further supporting its scientific validity as a treatment candidate for DLB.
  • Future Development Plans: CervoMed plans to initiate a pivotal global Phase 3 trial in the second half of 2026, focusing on DLB patients without AD co-pathology, indicating the company's long-term commitment to this field and highlighting its need for funding.
Newsfilter
2.0
02-18Newsfilter
CervoMed's Neflamapimod Approved for ALS Trials
  • Trial Launch: CervoMed's Neflamapimod has been included in the EXPERTS-ALS platform, with the first ALS patient expected to be dosed by the end of 2026, marking a significant advancement in treatments for neurodegenerative diseases.
  • Funding Support: The trial costs are funded by the UK National Institute for Health and Care Research and leading motor neuron disease charities, highlighting the commitment to ALS research and support.
  • Efficacy Assessment: Neflamapimod will be evaluated in approximately 35 ALS patients over 18-24 weeks, focusing on its impact on the neurodegeneration biomarker NfL, with potential further evaluation expanding to 80 patients.
  • Scientific Rationale: Neflamapimod selectively inhibits p38 MAP kinase to reduce neurotoxicity, demonstrating a favorable safety and efficacy profile, potentially offering new treatment hope for ALS patients.
Benzinga
6.5
01-15Benzinga
Biotech Insider Buying Signals Strong, Three Companies Draw Attention
  • Insider Buying Signals: Summit Therapeutics has recently seen insider purchases, indicating management's confidence in its cancer drug's market potential, which could lead to significant stock price volatility in the future.
  • Neurological Drug Development: Annexon also reported insider buying, reflecting confidence in its antibody drugs targeting neurological diseases, despite the high clinical trial risks, the potential for success is substantial.
  • Cognitive Disorder Treatment: CervoMed's insider trading is noteworthy as its drug for Lewy body dementia shows market expectations for new therapies, although challenges in clinical trials remain significant.
  • Investor Strategy: Insider buying in biotech stocks is not a buy signal but a research prompt, urging investors to carefully assess company cash flow and market sentiment to avoid losses from market fluctuations.
Globenewswire
9.0
2025-12-04Globenewswire
CervoMed's Neflamapimod Shows Significant Improvement in DLB Patients in Phase 2b Trial
  • Clinical Trial Results: CervoMed's Phase 2b RewinD-LB trial demonstrated that neflamapimod significantly improved CDR-SB scores in DLB patients, achieving a 52% reduction compared to placebo over 16 weeks, indicating its potential as a treatment.
  • Biomarker Improvement: The treatment group showed a significant reduction in GFAP levels, suggesting that neflamapimod effectively targets neurodegenerative processes, reinforcing its scientific basis as a potential DLB therapy.
  • Future Trial Plans: CervoMed is set to initiate a global Phase 3 registrational trial in the second half of 2026 to further validate neflamapimod's efficacy, advancing its path to market.
  • Funding Support: The RewinD-LB trial received $21.3 million in NIH funding, covering 43 research sites across the U.S., U.K., and Netherlands, highlighting the broad support and potential impact of this research.
Wall Street analysts forecast CRVO stock price to rise
5 Analyst Rating
Wall Street analysts forecast CRVO stock price to rise
5 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
19.00
Averages
22.75
High
27.00
Current: 0.000
sliders
Low
19.00
Averages
22.75
High
27.00
Chardan
Buy
upgrade
$15 -> $21
AI Analysis
2026-03-17
Reason
Chardan
Price Target
$15 -> $21
AI Analysis
2026-03-17
upgrade
Buy
Reason
Chardan raised the firm's price target on CervoMed to $21 from $15 and keeps a Buy rating on the shares. The neflamapimod program is fully back on track following alignment reached with the FDA in November 2025 for a Phase 3 registrational study in dementia with Lewy bodies, the analyst tells investors in a research note. With strong efficacy data with the new neflamapimod product batch in the completed Phase 2 study and with alignment on patient selection, a new drug formulation reaching desired drug plasma levels, and a new higher dose in the planned Phase 3 study, the firm is increasingly confident in the successful outcome of the DLB program.
Roth Capital
Boobalan Pachaiyappan
Buy
downgrade
$19 -> $11
2026-03-17
Reason
Roth Capital
Boobalan Pachaiyappan
Price Target
$19 -> $11
2026-03-17
downgrade
Buy
Reason
Roth Capital analyst Boobalan Pachaiyappan lowered the firm's price target on CervoMed to $11 from $19 and keeps a Buy rating on the shares. The company's Q4/FY25 financial results and corporate update were largely aligned with the firm's expectations, the analyst tells investors in a research note. While the company's 2H26 calendar is heavily loaded with multiple catalysts, the firm earnestly looks forward to Phase 3 Dementia with Lewy Bodies study initiation, given "solid" Phase 2 OLE study results and the first-mover advantage. The firm added that it cut its price target based on model updates reflecting the need to raise capital under less attractive terms.
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Valuation Metrics

The current forward P/E ratio for CervoMed Inc (CRVO.O) is -3.46, compared to its 5-year average forward P/E of -5.70. For a more detailed relative valuation and DCF analysis to assess CervoMed Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.70
Current PE
-3.46
Overvalued PE
-2.21
Undervalued PE
-9.20

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.12
Current EV/EBITDA
-0.96
Overvalued EV/EBITDA
-0.09
Undervalued EV/EBITDA
-6.16

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
18.09
Current PS
44.41
Overvalued PS
30.09
Undervalued PS
6.09

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Frequently Asked Questions

What is CervoMed Inc (CRVO) stock price today?

The current price of CRVO is 3.92 USD — it has decreased -2.49

What is CervoMed Inc (CRVO)'s business?

CervoMed Inc. is a clinical-stage company focused on developing treatments for age-related neurologic disorders. The Company is developing neflamapimod, an investigational, orally administered small molecule brain penetrant that inhibits p38 mitogen-activated protein kinase alpha. Neflamapimod has the potential to treat synaptic dysfunction, the reversible aspect of the underlying neurodegenerative processes that cause disease in Lewy bodies (DLB) and certain other neurological disorders. It focuses on reducing the impact of inflammation in the brain, or neuroinflammation, which is a key factor in the manifestation of degenerative diseases of the brain, including DLB. Neflamapimod is being evaluated in the Company's ongoing RewinD-LB Trial, a Phase 2b trial in patients with DLB.

What is the price predicton of CRVO Stock?

Wall Street analysts forecast CRVO stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CRVO is22.75 USD with a low forecast of 19.00 USD and a high forecast of 27.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is CervoMed Inc (CRVO)'s revenue for the last quarter?

CervoMed Inc revenue for the last quarter amounts to 8.73K USD, decreased -99.60

What is CervoMed Inc (CRVO)'s earnings per share (EPS) for the last quarter?

CervoMed Inc. EPS for the last quarter amounts to -0.87 USD, increased 12.99

How many employees does CervoMed Inc (CRVO). have?

CervoMed Inc (CRVO) has 15 emplpoyees as of March 25 2026.

What is CervoMed Inc (CRVO) market cap?

Today CRVO has the market capitalization of 36.29M USD.