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CALC Overview

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0.000(0.000%)Aft-market
ET
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0.000
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ET
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Intellectia

Loading chart...

High
0.738
Open
0.730
VWAP
0.69
Vol
239.70K
Mkt Cap
10.63M
Low
0.652
Amount
165.03K
EV/EBITDA(TTM)
--
Total Shares
15.74M
EV
8.19M
EV/OCF(TTM)
--
P/S(TTM)
--
CalciMedica, Inc. is a clinical-stage biopharmaceutical company. The Company focused on developing novel calcium release-activated calcium (CRAC) channel inhibition therapies for inflammatory and immunologic diseases. The Company's technology targets the inhibition of CRAC channels to modulate the immune response and protect against tissue cell injury. Its lead product candidate is Auxora, a potent and selective intravenous formulated small molecule CRAC channel inhibitor containing the active compound zegocractin (formerly referred to as CM4620) that, in animal models, reduced acute epithelial and/or endothelial cell injury and inflammation in organs, such as the pancreas, lungs and kidneys. The Company is conducting a Phase IIb trial (called CARPO) for acute pancreatitis (AP) with systemic inflammatory response syndrome (SIRS), as well as supporting the ongoing Phase I/II asparaginase-induced pancreatic toxicity (AIPT) study (called CRSPA).
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Events Timeline

(ET)
2026-03-03
17:00:00
CalciMedica Files $125M Mixed Securities Shelf
select
2026-01-28 (ET)
2026-01-28
10:40:00
Calcimedica Inc Trading Halted Due to Volatility
select
2026-01-28
07:10:00
CalciMedica Discontinues Phase 2 Clinical Trial of Auxora
select
2025-11-12 (ET)
2025-11-12
07:10:03
CalciMedica reveals publication of preclinical study on CM5480 in JCI
select
2025-11-12
07:04:00
CalciMedica announces Q3 earnings per share of 52 cents, surpassing consensus estimate of 41 cents.
select

News

seekingalpha
9.5
03-03seekingalpha
CalciMedica Reports FY GAAP EPS of -$1.97
  • Financial Performance: CalciMedica's reported FY GAAP EPS of -$1.97 indicates significant challenges in profitability, which may negatively impact investor confidence and stock performance.
  • Cash Position: As of December 31, 2025, the company holds $13.0 million in cash, cash equivalents, and short-term investments, suggesting a tight liquidity situation that necessitates careful cash management to sustain operations.
  • Operational Outlook: The company expects its cash reserves to be sufficient to fund its current operating plan into the fourth quarter of 2026, providing a degree of safety but still requiring vigilance regarding future funding needs and market conditions.
  • Market Reaction Potential: Despite the current poor financial performance, CalciMedica's future growth hinges on effective strategic execution and improvements in market conditions, prompting investors to closely monitor subsequent financial and operational developments.
Benzinga
6.0
01-29Benzinga
Wall Street Analysts Adjust Ratings
  • Analyst Rating Changes: Top Wall Street analysts have adjusted their ratings on several companies, reflecting varying market perspectives that could influence investor decisions and market trends.
  • Upgrades and Downgrades: The rating changes include upgrades and downgrades for certain stocks, prompting investors to pay attention to these shifts to assess potential investment opportunities and risks.
  • Market Reaction Expectations: Analyst rating adjustments may lead to short-term volatility in the affected stocks, necessitating that investors closely monitor market dynamics to seize optimal trading opportunities.
  • Source of Investment Advice: While the article does not provide specific stock names or rating details, investors can visit the analyst ratings page for a more comprehensive view of the information and recommendations available.
stocktwits
2.0
01-28stocktwits
CalciMedica Discontinues Trial, Stock Faces Volatility
  • Trial Discontinuation: CalciMedica announced the discontinuation of its Auxora trial for acute kidney injury patients due to safety concerns raised by an independent data monitoring committee, resulting in a 76% drop in stock price at Wednesday's close, followed by an additional 4% decline in after-hours trading.
  • Safety Reevaluation: Although no deaths or serious adverse events related to the study drug occurred, the committee's recommendation to reevaluate the study design, particularly patient enrollment criteria, could significantly impact the future clinical testing strategy for Auxora.
  • Analyst Perspective: Oppenheimer views CalciMedica's stock as significantly undervalued following the announcement, asserting that even without revenue potential from AKI, the $200 million opportunity in acute pancreatitis supports a favorable outlook, maintaining an 'Outperform' rating.
  • Market Sentiment Shift: On Stocktwits, retail sentiment around CALC stock surged from 'bearish' to 'extremely bullish' within 24 hours, with message volume increasing from 'low' to 'extremely high', indicating strong investor hopes for a price rebound.
Benzinga
9.0
01-28Benzinga
CalciMedica Halts KOURAGE Clinical Trial Amid Safety Concerns
  • Trial Discontinuation: CalciMedica announced the halt of its Phase 2 KOURAGE clinical trial evaluating Auxora for acute kidney injury due to recommendations from the Independent Data Monitoring Committee, leading to a significant drop in stock price.
  • Safety Concerns: While no deaths or serious adverse events occurred during the trial, safety issues identified by the IDMC necessitated a reevaluation of the study design, particularly regarding patient enrollment criteria, impacting future clinical evaluations.
  • Weak Stock Performance: CalciMedica shares are currently trading at $0.99, 83.5% below the 20-day simple moving average, with a 65.68% decline over the past year, reflecting ongoing challenges for the company.
  • Future Outlook: Despite the trial's discontinuation, CalciMedica remains optimistic about Auxora's potential in treating acute inflammatory illnesses and plans to finalize the pivotal trial design for acute pancreatitis in the first half of 2026, indicating strategic foresight.
Benzinga
4.5
01-28Benzinga
U.S. Stocks Mixed as Energy Shares Rise Amid Crude Inventory Decline
  • Mixed Market Performance: U.S. stocks showed mixed results on Wednesday, with the S&P 500 falling approximately 0.1%, while the Dow Jones rose 0.02% to 49,012.75 points, indicating market uncertainty.
  • Energy Sector Gains: Energy shares increased by 0.7% during Wednesday's trading, reflecting optimistic expectations for energy demand despite the overall market's poor performance.
  • Crude Inventory Decline: U.S. crude stocks fell by 2.296 million barrels for the week ending January 23, significantly lower than the market's expected increase of 1.75 million barrels, suggesting supply constraints that could drive oil prices higher.
  • Mortgage Applications Drop: The volume of mortgage applications decreased by 8.5% in the week ending January 23, indicating a weakening demand for home purchases that may impact the recovery of the real estate market.
Benzinga
4.5
01-28Benzinga
U.S. Stocks Mostly Higher; Starbucks Beats Q1 Sales Expectations
  • Market Performance: U.S. stocks traded mostly higher on Wednesday, with the Nasdaq Composite gaining around 150 points and the S&P 500 rising 0.31% to 6,999.99, indicating positive market sentiment and increased investor confidence.
  • Starbucks Earnings: Starbucks Corporation (NASDAQ:SBUX) shares rose about 5% on Wednesday, despite adjusted earnings of 56 cents per share missing market expectations of 59 cents, as sales of $9.915 billion exceeded expectations of $9.630 billion, showcasing strong sales growth.
  • Sector Dynamics: Consumer discretionary stocks gained 0.9%, while healthcare stocks fell by 0.7%, reflecting a divergence in investor sentiment across different sectors, which may influence future investment strategies.
  • Commodity Markets: Oil prices rose 1.3% to $63.19, gold increased by 3.7% to $5,272.90, and silver surged 8.4% to $114.830, indicating active commodity markets and heightened demand for safe-haven assets.
Wall Street analysts forecast CALC stock price to rise
1 Analyst Rating
Wall Street analysts forecast CALC stock price to rise
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
20.00
Averages
20.00
High
20.00
Current: 0.000
sliders
Low
20.00
Averages
20.00
High
20.00
Oppenheimer
Oppenheimer
Outperform
downgrade
$20 -> $10
AI Analysis
2026-03-05
Reason
Oppenheimer
Oppenheimer
Price Target
$20 -> $10
AI Analysis
2026-03-05
downgrade
Outperform
Reason
Oppenheimer lowered the firm's price target on CalciMedica to $10 from $20 and keeps an Outperform rating on the shares. The firm notes CalciMedica reported updates to its programs in acute kidney injury and acute pancreatitis along with quarterly financials. The most important development is the absence of any drug-related toxicity following thorough internal/external review of the unblinded Phase 2 KOURAGE dataset - as CalciMedica had indicated after voluntarily discontinuing the trial in late January.
H.C. Wainwright
H.C. Wainwright
Buy -> Neutral
downgrade
2026-01-29
Reason
H.C. Wainwright
H.C. Wainwright
Price Target
2026-01-29
downgrade
Buy -> Neutral
Reason
H.C. Wainwright downgraded CalciMedica to Neutral from Buy without a price target. The immediate discontinuation for the Phase 2 KOURAGE clinical trial in acute kidney injury removes a major catalyst for the shares, the analyst tells investors in a research note. The firm looks to upcoming safety and population clarity as the company reviews the unblinded dataset to determine a potential path forward.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for CALC
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Valuation Metrics

The current forward P/E ratio for CalciMedica Inc (CALC.O) is -3.49, compared to its 5-year average forward P/E of -1.88. For a more detailed relative valuation and DCF analysis to assess CalciMedica Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-1.88
Current PE
-3.49
Overvalued PE
-0.93
Undervalued PE
-2.82

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.70
Current EV/EBITDA
-2.68
Overvalued EV/EBITDA
-0.08
Undervalued EV/EBITDA
-1.32

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

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Frequently Asked Questions

What is CalciMedica Inc (CALC) stock price today?

The current price of CALC is 0.675 USD — it has decreased -7.66

What is CalciMedica Inc (CALC)'s business?

CalciMedica, Inc. is a clinical-stage biopharmaceutical company. The Company focused on developing novel calcium release-activated calcium (CRAC) channel inhibition therapies for inflammatory and immunologic diseases. The Company's technology targets the inhibition of CRAC channels to modulate the immune response and protect against tissue cell injury. Its lead product candidate is Auxora, a potent and selective intravenous formulated small molecule CRAC channel inhibitor containing the active compound zegocractin (formerly referred to as CM4620) that, in animal models, reduced acute epithelial and/or endothelial cell injury and inflammation in organs, such as the pancreas, lungs and kidneys. The Company is conducting a Phase IIb trial (called CARPO) for acute pancreatitis (AP) with systemic inflammatory response syndrome (SIRS), as well as supporting the ongoing Phase I/II asparaginase-induced pancreatic toxicity (AIPT) study (called CRSPA).

What is the price predicton of CALC Stock?

Wall Street analysts forecast CALC stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CALC is20.00 USD with a low forecast of 20.00 USD and a high forecast of 20.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is CalciMedica Inc (CALC)'s revenue for the last quarter?

CalciMedica Inc revenue for the last quarter amounts to -4.38M USD, decreased -28.95

What is CalciMedica Inc (CALC)'s earnings per share (EPS) for the last quarter?

CalciMedica Inc. EPS for the last quarter amounts to -4858000.00 USD, decreased -2.33

How many employees does CalciMedica Inc (CALC). have?

CalciMedica Inc (CALC) has 16 emplpoyees as of March 11 2026.

What is CalciMedica Inc (CALC) market cap?

Today CALC has the market capitalization of 10.63M USD.