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ATHE Overview

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Intellectia

Loading chart...

High
3.610
Open
3.510
VWAP
3.55
Vol
2.90K
Mkt Cap
64.44M
Low
3.491
Amount
10.29K
EV/EBITDA(TTM)
--
Total Shares
18.13M
EV
48.78M
EV/OCF(TTM)
--
P/S(TTM)
66.35
Alterity Therapeutics Limited is an Australia-based clinical-stage biotechnology company. The Company is focused on developing disease modifying treatments for neurodegenerative diseases. The Company's lead asset, ATH434, is to treat various Parkinsonian disorders. ATH434 is an oral agent designed to inhibit the aggregation of pathological proteins implicated in neurodegeneration. It has the potential to treat Parkinson's disease, as well as various Parkinsonian disorders, such as Multiple System Atrophy (MSA). The Company also has a drug discovery platform generating patentable chemical compounds to intercede in disease processes. Its lead asset, ATH434, is in a randomized, double blind, placebo-controlled Phase II clinical trial in participants with MSA. The Company is also conducting various nonclinical studies with ATH434 for use in Parkinson’s disease based on imaging of brain iron, preservation of neurons, and improvements in motor performance.
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Events Timeline

(ET)
2026-03-30
07:40:00
Alterity Therapeutics Receives FDA Feedback to Advance ATH434 Phase 3 Development
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2026-03-04 (ET)
2026-03-04
07:30:00
Alterity Therapeutics Appoints Daniel Claassen as Chief Medical Advisor
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2026-01-30 (ET)
2026-01-30
07:30:00
Alterity Therapeutics Releases December 2025 Quarterly Cash Flow Report
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2026-01-21 (ET)
2026-01-21
07:30:00
Alterity Therapeutics Aims to Advance ATH434 into Phase 3 in 2026
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2025-11-10 (ET)
2025-11-10
07:56:15
Alterity Therapeutics Shares Findings on OH from ATH434-201 Trial
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2025-10-31 (ET)
2025-10-31
07:29:07
Alterity Therapeutics announces cash reserves of A$54.46 million as of September 30.
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2025-10-09 (ET)
2025-10-09
07:29:15
Alterity Therapeutics Reveals Findings from Phase 2 Trial of ATH434
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2025-09-15 (ET)
2025-09-15
07:27:25
Alterity Therapeutics Reveals Phase 2 Data for ATH434-201
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News

Newsfilter
9.0
03-30Newsfilter
Alterity Receives Positive FDA Feedback to Advance Phase 3 Trial for MSA
  • FDA Meeting Outcome: Alterity Therapeutics received positive feedback from the FDA during a Type C meeting, confirming alignment on readiness for its Phase 3 clinical trial in Multiple System Atrophy (MSA), marking a significant milestone in the drug development process.
  • Clinical Development Plan: The planned Phase 3 trial will build on positive data from its Phase 2 clinical trials, where ATH434 demonstrated significant efficacy in randomized, double-blind studies, establishing a solid foundation for subsequent clinical testing.
  • Future Discussion Preparation: Alterity aims to reach agreement with the FDA on Chemistry, Manufacturing, and Controls (CMC) and the Phase 3 trial design, with today's favorable outcome paving the way for an End-of-Phase 2 meeting scheduled for mid-2026.
  • Strategic Implications: The FDA's support not only enhances Alterity's market competitiveness in the neurodegenerative disease sector but also instills confidence in the company's long-term growth prospects in the MSA field, potentially attracting more investor interest in its future developments.
NASDAQ.COM
9.0
03-30NASDAQ.COM
Alterity Receives Positive FDA Feedback for ATH434 Phase 3 Program
  • Regulatory Feedback Positive: Alterity Therapeutics received positive feedback from the FDA during a Type C Meeting, supporting its planned Phase 3 development program for ATH434 in Multiple System Atrophy (MSA), indicating confidence in clinical trial readiness.
  • Clinical Plan Confirmation: The FDA's written feedback addressed both clinical pharmacology and non-clinical development aspects, further confirming Alterity's strategic direction in advancing to the next stage of clinical testing, enhancing investor confidence in its R&D capabilities.
  • Multidisciplinary Strategy Implementation: This meeting is part of Alterity's multidisciplinary strategy to ensure alignment with the FDA for the smooth initiation of a pivotal Phase 3 trial, demonstrating the company's forward-looking planning in drug development.
  • Stable Market Performance: On the Australian Securities Exchange, ATH.AX traded at A$0.0080, unchanged from the previous session, reflecting a cautiously optimistic market sentiment regarding the company's future developments.
Newsfilter
1.0
03-09Newsfilter
Alterity Therapeutics CEO to Participate in Healthcare Summit
  • CEO Summit Participation: David Stamler, CEO of Alterity Therapeutics, will participate in the Bell Potter Healthcare Horizons Summit on March 12-13, 2026, in Sorrento, Australia, engaging in a fireside chat titled 'Optimising Late-stage Clinical Trials to Increase the Odds,' aimed at enhancing the company's visibility among investors.
  • Clinical Trial Progress: Alterity is preparing to initiate a Phase 3 pivotal trial for its lead asset ATH434 targeting Multiple System Atrophy (MSA), a rapidly progressive disease, with previous Phase 2 trials demonstrating clinically meaningful efficacy, which is expected to lay the groundwork for future market introduction.
  • Drug Discovery Platform: The company boasts a broad drug discovery platform focused on generating patentable compounds to address the underlying pathology of neurodegenerative diseases, indicating its innovative capabilities and market potential in this sector.
  • Company Background: Alterity Therapeutics is a clinical-stage biotechnology firm dedicated to creating an alternate future for individuals with neurodegenerative diseases, operating from dual headquarters in Melbourne and San Francisco, reflecting its global business strategy.
NASDAQ.COM
5.0
03-04NASDAQ.COM
Alterity Appoints New Chief Medical Advisor
  • Executive Appointment: Alterity Therapeutics has appointed Daniel Claassen as Chief Medical Advisor, effective March 2026, bringing strategic guidance to the company through his extensive experience in neurology.
  • Academic Credentials: Claassen is a Professor of Neurology at Vanderbilt University Medical Center and previously served as Chief of the Division of Behavioral and Cognitive Neurology, enhancing the company's clinical development capabilities with his academic achievements.
  • Research Leadership: As CEO of the Huntington's Study Group, Claassen oversees international research initiatives and organizational strategy aimed at accelerating therapy development, which will aid Alterity in advancing its new therapeutic candidates.
  • Market Reaction: Despite this significant appointment, Alterity's stock price fell by 1.45% to $3.4 on Nasdaq, indicating market caution regarding the company's future prospects.
Newsfilter
5.0
03-04Newsfilter
Alterity Appoints New Chief Medical Advisor
  • New Chief Medical Advisor: Alterity Therapeutics has appointed Dr. Daniel O. Claassen as Chief Medical Advisor, effective March 2026, bringing extensive experience in neurodegenerative diseases to guide the company's ATH434 program.
  • Rich Clinical Trial Experience: With over 20 years of research in movement disorders and cognitive neuroscience, Dr. Claassen has served as principal investigator on numerous clinical trials, which will facilitate the advancement of ATH434 into Phase 3 pivotal trials.
  • Strategic Development Opportunity: Dr. Claassen's appointment comes at a crucial time as Alterity prepares to initiate Phase 3 trials for MSA, and his deep understanding of the ATH434 program will provide robust support for the company's strategic growth in neurodegenerative disease treatments.
  • Positive Clinical Outlook: ATH434 demonstrated significant efficacy in Phase 2 trials, and Dr. Claassen's involvement is expected to accelerate the development of new therapies, addressing the urgent need for disease-modifying treatments.
Newsfilter
9.0
03-02Newsfilter
Alterity Advances ATH434 in Late-Stage Development for Multiple System Atrophy
  • Clinical Trial Progress: Alterity Therapeutics is advancing its candidate drug ATH434 in clinical development for Multiple System Atrophy (MSA), a rapidly progressive neurodegenerative disease with no approved therapies, demonstrating significant clinical benefits and a favorable safety profile.
  • Efficacy Data: In the Phase 2 clinical trial of ATH434, 77 participants underwent 12 months of treatment, with results showing significant improvements in functional ratings compared to placebo, indicating its potential to enhance patients' daily living capabilities.
  • Biomarker Application: The clinical program incorporates biomarkers and advanced neuroimaging to better assess disease progression and therapeutic impact, thereby supporting the development of disease-modifying therapies and enhancing understanding of this complex condition.
  • Patient Advocacy and Awareness: During MSA Awareness Month, Alterity will share educational information via social media, emphasizing support for the MSA community and showcasing the company's commitment to addressing the significant unmet needs in this field.

Valuation Metrics

The current forward P/E ratio for Alterity Therapeutics Ltd (ATHE.O) is 0.00, compared to its 5-year average forward P/E of -19.92. For a more detailed relative valuation and DCF analysis to assess Alterity Therapeutics Ltd's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-19.92
Current PE
0.00
Overvalued PE
84.10
Undervalued PE
-123.94

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.91
Current EV/EBITDA
-3.96
Overvalued EV/EBITDA
0.67
Undervalued EV/EBITDA
-2.50

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
10.78
Current PS
50.59
Overvalued PS
21.82
Undervalued PS
-0.26

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Frequently Asked Questions

What is Alterity Therapeutics Ltd (ATHE) stock price today?

The current price of ATHE is 3.5553 USD — it has decreased -2.23

What is Alterity Therapeutics Ltd (ATHE)'s business?

Alterity Therapeutics Limited is an Australia-based clinical-stage biotechnology company. The Company is focused on developing disease modifying treatments for neurodegenerative diseases. The Company's lead asset, ATH434, is to treat various Parkinsonian disorders. ATH434 is an oral agent designed to inhibit the aggregation of pathological proteins implicated in neurodegeneration. It has the potential to treat Parkinson's disease, as well as various Parkinsonian disorders, such as Multiple System Atrophy (MSA). The Company also has a drug discovery platform generating patentable chemical compounds to intercede in disease processes. Its lead asset, ATH434, is in a randomized, double blind, placebo-controlled Phase II clinical trial in participants with MSA. The Company is also conducting various nonclinical studies with ATH434 for use in Parkinson’s disease based on imaging of brain iron, preservation of neurons, and improvements in motor performance.

What is the price predicton of ATHE Stock?

Wall Street analysts forecast ATHE stock price to fall over the next 12 months. According to Wall Street analysts, the average 1-year price target for ATHE is USD with a low forecast of USD and a high forecast of USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Alterity Therapeutics Ltd (ATHE)'s revenue for the last quarter?

Alterity Therapeutics Ltd revenue for the last quarter amounts to NaN USD, decreased

What is Alterity Therapeutics Ltd (ATHE)'s earnings per share (EPS) for the last quarter?

Alterity Therapeutics Ltd. EPS for the last quarter amounts to USD, decreased

How many employees does Alterity Therapeutics Ltd (ATHE). have?

Alterity Therapeutics Ltd (ATHE) has 9 emplpoyees as of April 03 2026.

What is Alterity Therapeutics Ltd (ATHE) market cap?

Today ATHE has the market capitalization of 64.44M USD.