Teva and Blackstone Life Sciences Announce $400M Strategic Funding Agreement
Teva Pharmaceuticals, a U.S. affiliate of Teva (TEVA) and funds managed by Blackstone Life Sciences (BX) announced a $400M strategic funding agreement spread across four years to support the continued clinical development of duvakitug. Additionally, under the terms of the agreement, Blackstone Life Sciences will be eligible for regulatory and commercial milestones as well as royalties on duvakitug worldwide sales. Duvakitug is a human monoclonal antibody targeting TL1A, a promising target with the potential for broad therapeutic application across multiple indications. Under a separate and independent agreement announced in 2023, Teva is co-developing and, subject to regulatory approval, will be co-commercializing this asset with Sanofi (SNY). Duvakitug is currently in phase 3 clinical studies for the treatment of ulcerative colitis and Crohn's disease. Both companies recently announced phase 2b duvakitug maintenance data demonstrating clinically meaningful durable efficacy in ulcerative colitis and Crohn's disease. Under the agreement, Blackstone Life Sciences will provide Teva $400M to fund ongoing and future development costs for duvakitug, spread over four years. As part of the funding arrangement and subject to the approval of duvakitug by the FDA, Teva will pay Blackstone Life Sciences a milestone payment. Blackstone Life Sciences will also be eligible to receive commercial milestones and low single-digit royalties on duvakitug worldwide sales, subject to customary terms and conditions.
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- Strategic Funding Agreement: Teva Pharmaceuticals has entered into a $400 million strategic funding agreement with Blackstone Life Sciences, with funds allocated over four years to support the clinical development of duvakitug, reflecting confidence in the drug's potential.
- Clinical Development Support: Blackstone Life Sciences will finance ongoing and future development costs for duvakitug, and upon FDA approval, Teva will pay milestone payments to Blackstone, further advancing the product's path to market.
- Market Potential: Duvakitug is a human monoclonal antibody targeting TL1A, currently in phase 3 clinical studies for ulcerative colitis and Crohn's disease, and successful commercialization could meet the urgent market demand for new therapies.
- Collaborative Development: Teva is co-developing duvakitug with Sanofi under a separate agreement, and subject to regulatory approval, will co-commercialize the asset, enhancing market competitiveness and expanding market share.
- Strategic Funding Agreement: Blackstone Life Sciences has secured a $400 million strategic funding agreement with Teva Pharmaceutical to support the development of duvakitug, a phase 3 asset for ulcerative colitis and Crohn's disease, with funds allocated over four years.
- Milestone Payment Structure: Teva will pay Blackstone a milestone payment upon duvakitug's approval, and Blackstone is also eligible for commercial milestones and low single-digit royalties on global sales, enhancing its revenue potential significantly.
- Co-Development and Commercialization: Duvakitug will be co-developed and co-commercialized with Sanofi, a partnership that not only facilitates resource sharing but also accelerates the product's market entry, thereby improving competitive positioning.
- Clinical Data Support: Teva and Sanofi released phase 2b maintenance data on duvakitug in February, demonstrating the drug's potential in treating inflammatory bowel disease, which lays a solid foundation for subsequent clinical development.










