Precigen (PGEN) to Announce Q4 Earnings on March 25
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 1 hour ago
0mins
Should l Buy PGEN?
Source: seekingalpha
- Earnings Announcement Schedule: Precigen (PGEN) is set to announce its Q4 earnings on March 25 after market close, with consensus EPS estimate at -$0.08 and revenue estimate at $8.29 million, reflecting cautious market sentiment regarding the company's financial performance.
- Historical Performance Review: Over the past two years, Precigen has only beaten EPS estimates 13% of the time and revenue estimates 25% of the time, indicating challenges in meeting market expectations, which may impact investor confidence.
- Industry Conference Participation: Precigen presented at the 44th Annual J.P. Morgan Healthcare Conference, enhancing its visibility in the biotech sector, and despite low financial expectations, it demonstrates the company's active engagement in the industry.
- Quantitative Rating Analysis: Seeking Alpha's quantitative rating on Precigen provides an in-depth analysis of the company's financial health, suggesting that despite current poor financial expectations, there remains a divergence in market views regarding its future potential.
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Analyst Views on PGEN
Wall Street analysts forecast PGEN stock price to rise
1 Analyst Rating
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 3.240
Low
9.00
Averages
9.00
High
9.00
Current: 3.240
Low
9.00
Averages
9.00
High
9.00
About PGEN
Precigen, Inc. is a discovery and clinical-stage biopharmaceutical company developing gene and cell therapies for improving outcomes for patients with unmet medical needs. The Company’s proprietary technology platforms develop product candidates designed to target urgent and intractable diseases in its core therapeutic areas of immuno-oncology, autoimmune disorders, and infectious diseases. It has developed a pipeline of therapies across multiple indications. The Company’s segments include Biopharmaceuticals and Exemplar. The Biopharmaceuticals segment is primarily comprised of the Company's legal entities as well as royalty interests in therapeutics and therapeutic platforms from companies not controlled by the Company. The Exemplar is composed of Exemplar Genetics LLC, doing business as Precigen Exemplar, its wholly owned subsidiary focused on developing research models and services for healthcare research applications.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
- Earnings Announcement Schedule: Precigen (PGEN) is set to announce its Q4 earnings on March 25 after market close, with consensus EPS estimate at -$0.08 and revenue estimate at $8.29 million, reflecting cautious market sentiment regarding the company's financial performance.
- Historical Performance Review: Over the past two years, Precigen has only beaten EPS estimates 13% of the time and revenue estimates 25% of the time, indicating challenges in meeting market expectations, which may impact investor confidence.
- Industry Conference Participation: Precigen presented at the 44th Annual J.P. Morgan Healthcare Conference, enhancing its visibility in the biotech sector, and despite low financial expectations, it demonstrates the company's active engagement in the industry.
- Quantitative Rating Analysis: Seeking Alpha's quantitative rating on Precigen provides an in-depth analysis of the company's financial health, suggesting that despite current poor financial expectations, there remains a divergence in market views regarding its future potential.
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- Financial Results Announcement: Precigen will release its full year 2025 financial results and provide business updates on March 25, 2026, demonstrating the company's commitment to transparency and investor communication.
- Conference Call Details: The company will host a conference call at 4:30 PM ET on the release day, with participants encouraged to dial in 10-15 minutes early to ensure timely connection, reflecting the importance of investor relations.
- Innovative Drug Development: Precigen focuses on advancing precision medicines for difficult-to-treat diseases, committed to moving scientific breakthroughs from proof-of-concept to commercialization, highlighting its strategic positioning in the biopharmaceutical sector.
- Cautionary Forward-Looking Statements: The press release includes forward-looking statements, emphasizing the risks and uncertainties associated with the company's future plans, reminding investors to consider potential market fluctuations and operational changes.
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- Standard of Care Shift: Precigen's consensus paper recommends PAPZIMEOS as the new first-line treatment for adults with recurrent respiratory papillomatosis (RRP), marking a significant shift from repeated surgeries to HPV-targeted immunotherapy, greatly enhancing treatment options for patients.
- Clinical Experience Backing: Authored by 16 leading physicians, the paper emphasizes the safety and efficacy of PAPZIMEOS based on extensive clinical experience and literature review, providing physicians with a clear treatment algorithm aimed at reducing surgical risks for patients.
- Significant Patient Impact: With approximately 27,000 adult RRP patients in the U.S., the FDA approval of PAPZIMEOS offers the first treatment addressing the root cause of the disease, potentially improving patients' quality of life and reducing healthcare burdens significantly.
- Multidisciplinary Care Advocacy: The paper underscores the importance of shared decision-making and multidisciplinary care, promoting early therapy to avoid the risks associated with repeated surgeries, thus providing a more comprehensive management strategy for RRP patients.
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- Rapid Commercialization: Precigen's PAPZIMEOS, approved by the FDA in August 2025, is now being prescribed nationwide, with patient registrations doubling since November to over 200, reflecting strong market demand and enthusiastic physician engagement.
- Expanded Coverage: PAPZIMEOS is now covered by private health plans for approximately 170 million lives in the U.S., including most major insurers, and is also included under Medicare and Medicaid, significantly enhancing patient access.
- European Market Expansion: The European Medicines Agency has validated the Marketing Authorization Application for PAPZIMEOS, marking a significant step in Precigen's global expansion efforts, which is expected to create new growth opportunities for the company.
- Optimistic Financial Outlook: The company anticipates that its current capital resources will fund operations until cash flow break-even, and with the rapid rollout of PAPZIMEOS, there is substantial potential for future revenue growth, further solidifying its leadership in RRP treatment.
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- Conference Presentation: Precigen CEO Helen Sabzevari, PhD, is scheduled to present at the 44th Annual J.P. Morgan Healthcare Conference on January 15, 2026, at 7:30 AM PT in San Francisco, showcasing the company's advancements in precision medicine to attract investor interest and enhance visibility.
- Industry Engagement: Dr. Sabzevari will also participate in a fireside chat hosted by commercialization partner Eversana on January 12, 2026, at 10:30 AM PT, discussing strategic commercialization operations and strengthening connections within the biotech industry.
- Innovative Drug Development: Precigen focuses on advancing innovative precision medicines for difficult-to-treat diseases, demonstrating its robust R&D capabilities by moving scientific breakthroughs from proof-of-concept to commercialization.
- Future Outlook: The company is actively advancing its product pipeline, particularly PAPZIMEOS™ for recurrent respiratory papillomatosis, which aims to provide new treatment options for high unmet patient needs, potentially positively impacting future revenue growth.
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- Stock Plunge: Ultragenyx Pharmaceutical's shares fell sharply by 42% to $19.84 on Monday, primarily due to the failure of its Phase 3 Orbit and Cosmic studies for setrusumab (UX143) in Osteogenesis Imperfecta, leading to a significant decline in market confidence.
- Clinical Trial Failure: The results from Mereo BioPharma and Ultragenyx indicated that setrusumab did not achieve statistical significance in reducing the annualized clinical fracture rate, which not only impacts the company's short-term financial performance but may also have long-term negative implications for its future R&D investments and market competitiveness.
- Severe Market Reaction: The disappointing trial results raised investor concerns about Ultragenyx's future prospects, resulting in a substantial decrease in its market capitalization, reflecting the high sensitivity of investors to the success or failure of clinical trials in the biopharmaceutical sector.
- Industry Impact: Ultragenyx's failure could have a ripple effect across the biopharmaceutical industry, particularly in the bone metabolism disease space, as investors may adopt a more cautious approach towards similar product developments, potentially affecting financing and R&D strategies of related companies.
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