Pfizer Shares Rise on Upgraded Price Forecast
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jan 27 2026
0mins
Should l Buy PFE?
Source: Benzinga
- Forecast Upgrade: Cantor Fitzgerald raised Pfizer's price forecast from $24 to $27, providing a positive catalyst for the pharmaceutical giant despite a 1.6% decline in the broader healthcare sector.
- Licensing Agreement: Pfizer entered a non-exclusive licensing agreement with Novavax for its Matrix-M adjuvant technology, granting Novavax a $30 million upfront payment and potential milestones up to $500 million, indicating Pfizer's proactive approach in product development.
- FDA Breakthrough Therapy: Pfizer's Sutent, in combination with Cogent Biosciences' bezuclastinib, received FDA Breakthrough Therapy Designation after showing a 50% reduction in disease progression risk, enhancing Pfizer's competitive edge in oncology treatments.
- Leadership Warning: At the World Economic Forum, CEO Albert Bourla warned that reduced funding for U.S. universities has weakened America's position in global health research, highlighting China's dominance in health research rankings.
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Analyst Views on PFE
Wall Street analysts forecast PFE stock price to rise
16 Analyst Rating
5 Buy
11 Hold
0 Sell
Moderate Buy
Current: 27.370
Low
24.00
Averages
28.56
High
35.00
Current: 27.370
Low
24.00
Averages
28.56
High
35.00
About PFE
Pfizer Inc. is a research-based, global biopharmaceutical company. The Company is engaged in the discovery, development, manufacture, marketing, sale and distribution of biopharmaceutical products worldwide. Its Biopharma segment includes the Pfizer U.S. Commercial Division, and the Pfizer International Commercial Division. Its product categories include oncology, primary care and specialty care. Its oncology products include Ibrance, Xtandi, Padcev, Adcetris, Inlyta, Lorbrena, Bosulif, Tukysa, Braftovi, Mektovi, Orgovyx, Elrexfio, Tivdak and Talzenna. Its primary care products include Eliquis, Nurtec ODT/Vydura, Zavzpret, the Prevnar family, Comirnaty, Abrysvo, FSME/IMMUN-TicoVac, Nimenrix, Trumenba, and Paxlovid. Its specialty care products include Xeljanz, Enbrel (outside the United States and Canada), Inflectra, Abrilada, Cibinqo, Litfulo, Eucrisa, Velsipity, the Vyndaqel family, Genotropin, BeneFIX, Xyntha, Somavert, Ngenla, Hympavzi, Sulperazon, Zavicefta, Octagam and others.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.

- Clinical Trial Results: Pfizer's BRAFTOVI regimen demonstrated a statistically significant improvement in progression-free survival (PFS) for patients with specific mutations in metastatic colorectal cancer during the BREAKWATER trial, indicating its superior efficacy over traditional treatments.
- Efficacy Comparison: The BREAKWATER trial revealed a confirmed objective response rate (ORR) of 60.9% for BRAFTOVI, significantly higher than the 40.0% observed in patients receiving chemotherapy with or without bevacizumab, showcasing its potential in clinical applications.
- Market Performance Analysis: Pfizer's stock is currently priced at $27.75, trading 3.5% below its 20-day simple moving average, indicating short-term weakness, despite a 7.90% increase over the past 12 months.
- Analyst Ratings: The stock carries an average price target of $29.67, with analysts maintaining a neutral rating; adjustments from Cantor Fitzgerald and UBS reflect a cautious outlook on its future performance.
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- Survival Rate Improvement: The overall survival (OS) also demonstrated clinically meaningful prolongation, further validating the efficacy of BRAFTOVI and potentially offering a new treatment option for previously untreated BRAF V600E-mutant mCRC patients, addressing a significant unmet need.
- Safety Profile: At the time of the PFS analysis, the safety profile of BRAFTOVI was consistent with known components, with no new safety signals identified, suggesting a favorable safety profile that enhances its clinical applicability.
- FDA Submission Plans: Pfizer plans to submit detailed results to the FDA to support the potential approval of BRAFTOVI in combination with cetuximab and FOLFIRI for BRAF V600E-mutant mCRC patients, further advancing the drug's market prospects.
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- Regulatory Streamlining: Legislation passed by Congress in November simplifies the regulatory process for transitioning prescription drugs to OTC status, including full, conditional, and partial switch pathways, which is expected to accelerate drug availability and enhance patient convenience in medication access.
- Increased Transparency: Makary emphasized that OTC sales would bypass insurers and pharmacy benefit managers, potentially lowering drug prices and increasing transparency, with cash prices for OTC medications possibly being lower than patients' copays for prescription drugs, thereby alleviating financial burdens on patients.
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