Minerva Neurosciences Reports First Quarter 2025 Financial Results and Business Updates
Corporate Update: Minerva Neurosciences has regained compliance with Nasdaq listing rules and continues to engage with the FDA regarding its New Drug Application for roluperidone, aimed at treating negative symptoms of schizophrenia.
Financial Results: For Q1 2025, Minerva reported a net loss of $3.8 million, a decrease from $8.6 million in Q1 2024, with cash reserves at approximately $17.4 million as of March 31, 2025.
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Minerva Neurosciences to Host KOL Event on Schizophrenia Treatment
- KOL Event Announcement: Minerva Neurosciences will host a virtual KOL event on February 3, 2026, featuring experts in psychology and psychiatry to discuss the patient burden of negative symptoms of schizophrenia and assessment challenges, which is expected to provide critical insights for the upcoming Phase 3 trial.
- Clinical Trial Plans: The company plans to initiate a confirmatory Phase 3 trial in 2026 using a novel protocol aligned with FDA considerations, aimed at maximizing the probability of a successful outcome and addressing the unmet medical need for treating negative symptoms.
- Impact of Negative Symptoms: Approximately 50% to 60% of individuals with schizophrenia experience at least one primary negative symptom, highlighting the urgent medical need as current antipsychotics primarily address positive symptoms without efficacy against negative symptoms.
- Expert Backgrounds: The event will feature Gregory Strauss, PhD, and Brian Kirkpatrick, MD, both of whom have extensive experience in schizophrenia research and have received over $82 million in research funding, underscoring their authority in the field and potential influence on future treatment options.

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