Minerva Neurosciences Gains Ground with Up to $200M Funding to Develop Schizophrenia Treatment
Stock Surge: Minerva Neurosciences' shares increased by up to 160% premarket following the announcement of a financing deal worth up to $200 million and plans to resubmit the NDA for its schizophrenia drug, roluperidone.
Financing Details: The financing includes an $80 million upfront investment from the sale of Series A convertible preferred stock, with additional funds contingent on the exercise of warrants, aimed at supporting a Phase 3 trial and NDA resubmission.
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Minerva Neurosciences to Host KOL Event on Schizophrenia Treatment
- KOL Event Announcement: Minerva Neurosciences will host a virtual KOL event on February 3, 2026, featuring experts in psychology and psychiatry to discuss the patient burden of negative symptoms of schizophrenia and assessment challenges, which is expected to provide critical insights for the upcoming Phase 3 trial.
- Clinical Trial Plans: The company plans to initiate a confirmatory Phase 3 trial in 2026 using a novel protocol aligned with FDA considerations, aimed at maximizing the probability of a successful outcome and addressing the unmet medical need for treating negative symptoms.
- Impact of Negative Symptoms: Approximately 50% to 60% of individuals with schizophrenia experience at least one primary negative symptom, highlighting the urgent medical need as current antipsychotics primarily address positive symptoms without efficacy against negative symptoms.
- Expert Backgrounds: The event will feature Gregory Strauss, PhD, and Brian Kirkpatrick, MD, both of whom have extensive experience in schizophrenia research and have received over $82 million in research funding, underscoring their authority in the field and potential influence on future treatment options.

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