Longeveron Secures Patent in Japan for Potency Assay Methods
Longeveron announced that the Japan Patent Office, JPO, has granted a patent covering potency assay methods for assessing human mesenchymal stem cells, MSCs, derived from bone marrow, adipose tissue, peripheral blood, a lung, a heart, amniotic fluid, inner organs, an amniotic membrane, an umbilical cord or a placenta or differentiated from induced pluripotent stem cells, IPSCs. Japan Patent No. 2022-563984, entitled "Potency Assay," provides Longeveron with patent rights in Japan through April 20, 2041, assuming all annuity fees are paid. Potency assays are a crucial element for approved cell-based therapy products. "We are extremely encouraged by our growing portfolio of international patents protecting the novelty of our cell-based therapeutic products," said Dr. Joshua Hare, Executive Chairman and Chief Science Officer of Longeveron. "This issuance brings Longeveron's global intellectual property portfolio to 33 issued patents."
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Longeveron Secures Japanese Patent for Stem Cell Therapy Assays
- Patent Grant: The Japan Patent Office has granted Longeveron a patent covering potency assay methods for assessing human mesenchymal stem cells derived from various tissues, securing patent rights in Japan until 2041, thereby enhancing the protection of its clinical programs.
- Clinical Trial Progress: Longeveron's proprietary mesenchymal stem cell therapy, laromestrocel, has shown positive initial results across five clinical trials in three indications, demonstrating its potential in treating rare and aging-related diseases, which further solidifies its market position.
- Global Patent Portfolio Expansion: This patent issuance brings Longeveron's global intellectual property portfolio to 33 patents, reflecting the company's innovative capabilities in cell therapy and enhancing its competitive edge, potentially attracting more investor interest.
- Future Development Plans: Longeveron is conducting a pivotal Phase 2b clinical trial for HLHS, with results expected in Q3 2026, which may lay the groundwork for a Biologics License Application (BLA) with the FDA, further advancing its product commercialization efforts.

Longeveron Joins JPM Healthcare Week to Focus on Alzheimer's Disease
- Participation in Healthcare Summit: Longeveron will participate in the StartUp Health Alzheimer’s & Brain Health Moonshot during JPM Healthcare Week in January 2026, aiming to accelerate breakthroughs in Alzheimer’s and Parkinson’s diseases, showcasing its leadership in the biotechnology sector.
- Investor Meeting Arrangements: The company will host meetings with institutional investors and potential partners during the event, aiming to foster connections that could drive future funding and collaboration opportunities, thereby enhancing market confidence.
- Product Development Progress: Longeveron’s lead product, laromestrocel (LOMECEL-B®), is under development for multiple diseases including Alzheimer’s, having received five significant FDA designations, indicating its potential in clinical stages.
- Strategic Partnerships: By collaborating with the Alzheimer’s Drug Discovery Foundation and Gates Ventures, Longeveron further solidifies its position within the Health Moonshot initiative, demonstrating its commitment to addressing unmet medical needs.






