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LGVN Overview

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0.000(0.000%)Aft-market
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0.000
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ET
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Intellectia

Loading chart...

High
0.850
Open
0.774
VWAP
0.82
Vol
311.75K
Mkt Cap
26.54M
Low
0.762
Amount
254.86K
EV/EBITDA(TTM)
--
Total Shares
31.60M
EV
8.57M
EV/OCF(TTM)
--
P/S(TTM)
12.68
Longeveron Inc. is a clinical-stage biotechnology company developing regenerative medicines to address unmet medical needs. The Company’s lead investigational product is Lomecel-B, an allogeneic medicinal signaling cell (MSC) therapy product isolated from the bone marrow of young, healthy adult donors. Lomecel-B has multiple potential mechanisms of action, encompassing pro-vascular, pro-regenerative, anti-inflammatory, and tissue repair and healing effects with broad potential applications across a spectrum of disease areas. The Company is pursuing three pipeline indications: hypoplastic left heart syndrome (HLHS), Alzheimer’s disease, and Aging-related Frailty. Lomecel-B development programs have received five distinct FDA designations: for the HLHS program - Orphan Drug designation, Fast Track designation, and Rare Pediatric Disease designation; and, for the AD program - Regenerative Medicine Advanced Therapy (RMAT) designation and Fast Track designation.
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Events Timeline

(ET)
2026-05-13
16:40:00
Longeveron Q1 Revenue $398,000, Exceeds Expectations
select
2026-05-11 (ET)
2026-05-11
09:40:00
Longeveron ELPIS II Clinical Trial Approved to Continue
select
2026-05-08 (ET)
2026-05-08
16:20:00
Longeveron Holds Constructive Meeting with FDA
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2026-04-10 (ET)
2026-04-10
16:10:00
Longeveron Files to Sell 30.87M Shares of Class A Common Stock
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2026-04-08 (ET)
2026-04-08
09:30:00
Longeveron Secures Patent in China for Stem Cell Potency Assays
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2026-03-10 (ET)
2026-03-10
09:20:00
Longeveron Signs $30M Private Placement Agreement
select

News

Newsfilter
8.5
06-09Newsfilter
Longeveron Receives EMA SME Designation for Drug Development
  • EMA Certification Benefits: Longeveron has been granted Small or Medium-sized Enterprise (SME) status by the European Medicines Agency (EMA), enabling the company to receive scientific advice and protocol assistance during drug regulatory approval, thereby accelerating patient access to life-saving treatments.
  • Increased Success Rates: According to the EMA, companies with SME designation saw their success rate for marketing authorization applications exceed 89% in 2020, indicating that Longeveron will benefit from a higher probability of success in future drug approvals.
  • Multiple FDA Designations: Longeveron's lead product, laromestrocel (Lomecel-B), has received five significant FDA designations, including Orphan Drug and Fast Track designations, which will further enhance its competitive position in the market and attract investor confidence.
  • Broad Application Potential: As a living cell product derived from mesenchymal stem cells isolated from the bone marrow of young healthy adults, laromestrocel exhibits multiple mechanisms of action, including anti-inflammatory and pro-vascular regenerative responses, suggesting significant potential in treating various rare and aging-related diseases.
Newsfilter
8.5
06-04Newsfilter
Longeveron Highlights New Data on Stem Cell Therapy
  • Clinical Trial Progress: Longeveron's stem cell therapy laromestrocel has completed five clinical trials across three indications, with positive initial results indicating its potential in treating rare diseases, which is likely to attract increased investor interest.
  • Market Opportunity Assessment: The company estimates a total market opportunity of approximately $11 billion for its four primary indications, particularly highlighting Alzheimer's disease with a market potential exceeding $5 billion, underscoring the strategic significance of laromestrocel in addressing unmet medical needs.
  • Strategic Partnership Plans: Longeveron intends to meet with global pharmaceutical executives at the upcoming BIO International Convention to explore potential collaborations for HLHS, Alzheimer's disease, and other programs, aiming to accelerate time to market and enhance capital efficiency.
  • Intellectual Property Protection: Laromestrocel is backed by 52 global patents covering its composition, methods of use, and manufacturing processes, establishing a strong competitive moat that offers attractive opportunities for potential partners interested in late-stage clinical development.
seekingalpha
9.5
05-14seekingalpha
Longeveron Q1 2026 Earnings Call Insights
  • Financial Performance: In Q1 2026, Longeveron reported a net loss of $4.7 million, an improvement from $5 million in Q1 2025, indicating efforts in cost control but still facing financial pressures.
  • Clinical Trial Progress: The company anticipates top-line results from the ELPIS II trial in August 2026, although unfavorable FDA feedback on the primary endpoint highlights uncertainties in clinical development.
  • Strategic Shift: Longeveron is transitioning to a more capital-efficient asset-light operating model, focusing on securing strategic licensing partnerships to advance its stem cell product development, aiming to enhance market competitiveness.
  • Regulatory Challenges: The FDA has stated that the right ventricular ejection fraction is no longer considered an appropriate endpoint for demonstrating efficacy in the ELPIS II trial, which may impact future biological license application pathways, with management expressing cautious optimism about the situation.
Newsfilter
9.0
05-11Newsfilter
Longeveron Advances Phase 2b Trial for HLHS
  • Trial Progress: Longeveron's ELPIS II clinical trial has fully enrolled 40 pediatric patients to evaluate laromestrocel as an adjunct therapy for HLHS, with top-line results expected in August 2026, demonstrating the company's ongoing commitment to rare disease treatment.
  • Safety Assessment: The independent Data Monitoring Committee (DMC) completed its final safety assessment of the trial, identifying no new safety concerns and approving the study to continue as planned, indicating the potential safety and efficacy of the therapy.
  • FDA Designations: Laromestrocel has received Orphan Drug, Fast Track, and Rare Pediatric Disease designations from the FDA, highlighting its significance in HLHS treatment and potentially establishing a strong market opportunity for the company.
  • Market Need: HLHS affects approximately 1,000 infants annually in the U.S., and despite complex existing treatments, long-term mortality and morbidity remain substantial; the development of laromestrocel aims to address this unmet medical need, presenting significant market potential.
NASDAQ.COM
9.0
05-11NASDAQ.COM
Longeveron Advances FDA Discussions on ELPIS II Trial
  • FDA Meeting Outcome: Longeveron held a constructive Type C meeting with the FDA, which acknowledged HLHS as a rare disease with high unmet needs but indicated that the primary endpoint, right ventricular ejection fraction (RVEF), is insufficient to demonstrate efficacy, potentially impacting the company's future clinical trial strategies.
  • Trial Adjustment Limitations: While Longeveron agreed with the FDA's concerns, changes to the primary endpoint cannot be made mid-trial due to NIH-mandated interim analysis, meaning ELPIS II is no longer considered pivotal, which may delay its market approval process.
  • Future Plans: Longeveron intends to submit a Sponsor Statistical Analysis Plan (SAP) with a composite primary endpoint and secondary endpoints for FDA review, aiming to integrate more evidence to support a Biologics License Application (BLA), demonstrating the company's confidence in trial results.
  • Clinical Trial Context: Topline results from the 40-patient ELPIS II trial are anticipated in August 2026, capturing objective measures such as mortality, transplant-free survival, and major adverse cardiac events to support efficacy assessment, underscoring the importance of new therapies in HLHS treatment.
stocktwits
9.0
05-09stocktwits
FDA Raises Concerns Over Longeveron's Cell Therapy Trial Design
  • FDA Trial Design Concerns: The FDA explicitly stated that Longeveron's laromestrocel trial's current primary endpoint is “not appropriate to demonstrate efficacy,” resulting in the study no longer being considered “pivotal,” which could hinder future approval processes.
  • Clinical Trial Data Expectations: Despite the FDA's reservations about the trial design, Longeveron still anticipates top-line data from the 40-patient randomized controlled study in August 2026, which, if positive, could support future application filings.
  • Investor Sentiment Shift: Following the FDA meeting, retail sentiment around LGVN stock shifted from 'bearish' to 'neutral' within 24 hours, although the stock has fallen 43% over the past year, indicating cautious optimism among investors regarding future developments.
  • Revised Plan Submission: Longeveron plans to submit a revised plan featuring a composite primary endpoint and secondary endpoints, and while the FDA indicated it could not agree to a new primary endpoint during the ongoing trial, the company remains optimistic that the final dataset will support an application.
Wall Street analysts forecast LGVN stock price to rise
2 Analyst Rating
Wall Street analysts forecast LGVN stock price to rise
2 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
3.00
Averages
3.50
High
4.00
Current: 0.000
sliders
Low
3.00
Averages
3.50
High
4.00
Maxim
Maxim
Buy
to
Hold
downgrade
AI Analysis
2026-05-11
Reason
Maxim
Maxim
Price Target
AI Analysis
2026-05-11
downgrade
Buy
to
Hold
Reason
Maxim downgraded Longeveron to Hold from Buy.
H.C. Wainwright
Buy
downgrade
$10 -> $8
2026-05-04
Reason
H.C. Wainwright
Price Target
$10 -> $8
2026-05-04
downgrade
Buy
Reason
H.C. Wainwright lowered the firm's price target on Longeveron to $8 from $10 and keeps a Buy rating on the shares. The firm cites equity dilution for the target cut.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for LGVN
Unlock Now

Valuation Metrics

The current forward P/E ratio for Longeveron Inc (LGVN.O) is 0.00, compared to its 5-year average forward P/E of -3.91. For a more detailed relative valuation and DCF analysis to assess Longeveron Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.91
Current PE
0.00
Overvalued PE
0.21
Undervalued PE
-8.03

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.06
Current EV/EBITDA
-0.13
Overvalued EV/EBITDA
3.33
Undervalued EV/EBITDA
-9.45

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
65.85
Current PS
3.83
Overvalued PS
151.81
Undervalued PS
-20.10

Financials

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Frequently Asked Questions

What is Longeveron Inc (LGVN) stock price today?

The current price of LGVN is 0.84 USD — it has increased 9.09

What is Longeveron Inc (LGVN)'s business?

Longeveron Inc. is a clinical-stage biotechnology company developing regenerative medicines to address unmet medical needs. The Company’s lead investigational product is Lomecel-B, an allogeneic medicinal signaling cell (MSC) therapy product isolated from the bone marrow of young, healthy adult donors. Lomecel-B has multiple potential mechanisms of action, encompassing pro-vascular, pro-regenerative, anti-inflammatory, and tissue repair and healing effects with broad potential applications across a spectrum of disease areas. The Company is pursuing three pipeline indications: hypoplastic left heart syndrome (HLHS), Alzheimer’s disease, and Aging-related Frailty. Lomecel-B development programs have received five distinct FDA designations: for the HLHS program - Orphan Drug designation, Fast Track designation, and Rare Pediatric Disease designation; and, for the AD program - Regenerative Medicine Advanced Therapy (RMAT) designation and Fast Track designation.

What is the price predicton of LGVN Stock?

Wall Street analysts forecast LGVN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for LGVN is3.50 USD with a low forecast of 3.00 USD and a high forecast of 4.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Longeveron Inc (LGVN)'s revenue for the last quarter?

Longeveron Inc revenue for the last quarter amounts to 398.00K USD, increased 4.46

What is Longeveron Inc (LGVN)'s earnings per share (EPS) for the last quarter?

Longeveron Inc. EPS for the last quarter amounts to -0.19 USD, decreased -44.12

How many employees does Longeveron Inc (LGVN). have?

Longeveron Inc (LGVN) has 26 emplpoyees as of June 17 2026.

What is Longeveron Inc (LGVN) market cap?

Today LGVN has the market capitalization of 26.54M USD.