Galmed Secures New Patent for Aramchol, Extending Protection to 2042
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 04 2025
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Source: PRnewswire
- Patent Protection Extension: Galmed Pharmaceuticals has secured a new use patent for Aramchol in South Korea, extending global patent protection to 2042, thereby reinforcing its market leadership in the non-alcoholic steatohepatitis (NASH) sector.
- Clinical Readiness: As a first-in-class candidate ready for Phase 3 trials, Aramchol has demonstrated significant fibrosis improvement in clinical studies, indicating its potential in treating complex diseases.
- Combination Therapy Outlook: The new patent covers the combination therapy of Aramchol and Rezdiffra, aligning with the industry's shift towards combination therapies, which is expected to drive the initiation of clinical studies and meet market demand for effective treatments.
- Safety Advantage: Aramchol's excellent safety and tolerability make it an ideal candidate for combination with other MASH drugs, potentially enhancing its market acceptance and driving sales growth.
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About GLMD
Galmed Pharmaceuticals Ltd. is an Israel-based biopharmaceutical company dedicated to the development of therapeutics for the treatment of liver diseases. The Company is focused its research and development efforts on addressing unmet medical needs in the field of liver health. The Company's flagship product is Aramchol, a first-in-class synthetic fatty acid-bile acid conjugate molecule. Aramchol is aimed to be effective in the treatment of non-alcoholic steatohepatitis (NASH) in patients who are overweight or obese and have prediabetes or type II diabetes mellitus. The Company's drug aims to be efficient treatment of NASH, a chronic liver disease characterized by fat accumulation, inflammation, and fibrosis, which can lead to cirrhosis and liver cancer if left untreated.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Galmed Pharmaceuticals to Initiate Phase 1/2 Trial of Aramchol and Regorafenib in 2026
- Clinical Trial Launch: Galmed Pharmaceuticals announced the initiation of a Phase 1/2 clinical trial for the combination of Aramchol and Regorafenib in 2026, aimed at enhancing treatment efficacy for hepatocellular carcinoma and other GI cancers, marking a significant advancement in the company's liver disease treatment efforts.
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- Industry Recognition: The acceptance of Galmed's latest research findings at the HEP-DART 2025 meeting underscores the significance of its work in liver disease treatment, further enhancing the company's competitive position in the market.
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