KalVista announces Q3 EPS of 92 cents, compared to 84 cents in the previous year.
Launch Progress: The US launch of EKTERLY is gaining momentum due to strong early demand and rapid adoption among physicians and patients with hereditary angioedema (HAE).
Global Expansion: EKTERLY has recently been launched in Germany and received approval in Australia, marking five total regulatory approvals as the company aims for a global presence.
Financial Resources: KalVista has successfully closed a $144 million convertible note offering, providing the financial means to support its global launch strategy and long-term growth.
Market Confidence: There is a consistent increase in new patient starts and repeat prescriptions, indicating sustained confidence in EKTERLY's clinical value as the first oral on-demand treatment for HAE.
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- Price Increase Announcement: Stifel has raised the price target for KalVista Pharmaceuticals from $39 to $42.
- Market Implications: This adjustment reflects Stifel's updated outlook on KalVista's performance and potential in the pharmaceutical market.
- Product Revenue Growth: KalVista Pharmaceuticals achieved $49.1 million in global net product revenue for the eight-month transition period ending December 31, 2025, including $35.4 million in the fourth quarter, indicating steady growth since the launch of EKTERLY, although still in the early stages.
- Rising Operating Expenses: The company's operating expenses surged to $160.2 million, a 43% increase from $117 million in the prior year, primarily driven by the costs associated with commercial launch activities, reflecting the high costs of market promotion.
- Reduced R&D Spending: Research and development expenses were $33.4 million, down 36% from $52.2 million in the prior year, indicating a more cautious spending strategy on new product development in response to current financial pressures.
- Strong Cash Position: As of December 31, 2025, KalVista reported $300 million in cash and investments, believed to be sufficient to fund operations under the current plan, although the company has not yet provided long-term financial guidance.
- Revenue Growth: KalVista reported $49.1 million in global net product revenue for EKTERLY® (sebetralstat) for the eight months ending December 31, 2025, indicating strong market demand and rapid product adoption, which is expected to lay the groundwork for future profitability.
- Patient Initiation Metrics: By February 28, 2026, the company received 1,702 patient start forms in the US, representing nearly 20% of the total US patient population, and activated 724 unique prescribers, demonstrating EKTERLY's swift market penetration and acceptance.
- International Market Expansion: EKTERLY's launch in Japan, facilitated by partner Kaken Pharmaceutical Co., Ltd., has been listed on the National Health Insurance drug reimbursement price list, marking a significant step in the company's global market expansion and enhancing its international competitiveness.
- Significant Clinical Progress: The company completed enrollment in the KONFIDENT-KID Phase 3 trial for pediatric patients aged 2 to 11 a full year ahead of schedule, with plans to file a US new drug application in Q3 2026, further solidifying EKTERLY's position as a foundational therapy for HAE management.

Company Overview: Kalvista Pharmaceuticals is a biopharmaceutical company focused on developing treatments for diseases with high unmet medical needs.
Financial Report: The company reported earnings of $2.03 per share for the eight months ending December 31, 2025.
- Earnings Highlights: KalVista Pharmaceuticals reported a Q4 GAAP EPS of -$2.03, which may not be directly comparable to estimates, but revenue of $49.08 million exceeded expectations by $16.79 million, indicating strong market performance.
- Cash Position: As of December 31, 2025, the company had approximately $300.2 million in cash, cash equivalents, and marketable securities, ensuring operational funding for the next few years and supporting its strategy towards profitability.
- EKTERLY Sales Outlook: The anticipated cash reserves and projected revenues from EKTERLY sales are expected to fund the company through to profitability, reflecting confidence in the product's market potential.
- Future Growth Strategy: KalVista Pharmaceuticals aims to drive the next stage of growth by expanding EKTERLY's pediatric label, a strategy that not only broadens market coverage but could significantly enhance the company's future revenue potential.

- Company Overview: Kalvista Pharmaceuticals has reported a net product revenue of $49.1 million for the eight-month period ending December 31, 2025.
- Financial Performance: The revenue figure indicates the company's performance in the pharmaceutical market during the specified timeframe.








