Cabaletta Bio (CABA) Shares Rise Nearly 6% on Clinical Progress
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jan 20 2026
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Source: NASDAQ.COM
- Stock Price Surge: Cabaletta Bio's shares rose nearly 6% to $2.33 in premarket trading on Tuesday, indicating positive market sentiment regarding its clinical advancements.
- Clinical Trial Progress: The company's RESET program includes multiple ongoing trials for autoimmune diseases, with complete Phase 1/2 clinical data from the RESET-Myositis trial expected in 2025, highlighting significant research milestones.
- New Registrational Cohort Launch: Last month, Cabaletta initiated a registrational cohort for dermatomyositis and antisynthetase syndrome, further expanding its clinical research scope and demonstrating proactive positioning in the treatment landscape.
- Stable Market Performance: Over the past year, CABA's stock has fluctuated between $0.98 and $3.67, closing at $2.20 on Friday, up 5.77%, reflecting investor confidence in its future potential.
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Analyst Views on CABA
Wall Street analysts forecast CABA stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CABA is 15.86 USD with a low forecast of 4.00 USD and a high forecast of 30.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
9 Analyst Rating
8 Buy
1 Hold
0 Sell
Strong Buy
Current: 2.850
Low
4.00
Averages
15.86
High
30.00
Current: 2.850
Low
4.00
Averages
15.86
High
30.00
About CABA
Cabaletta Bio, Inc. is a clinical-stage biotechnology company focused on the discovery and development of engineered T cell therapies that have the potential to provide deep and durable, perhaps curative, responses with one-time administration for patients with autoimmune diseases. Its Cabaletta Approach to B cell Ablation (CABA) platform encompasses two strategies: Chimeric Antigen Receptor T cells for Autoimmunity (CARTA) and Chimeric AutoAntibody Receptor T cells (CAART). Resecabtagene autoleucel, its lead product candidate from its CARTA platform, is a 4-1BB co-stimulatory domain-containing fully human CD19-CAR T construct designed to treat patients with a range of autoimmune diseases. Its DSG3-CAART product candidate is being evaluated for the treatment of mPV, a subtype of PV that affects the epithelium of the mucous membranes, in the Phase 1 DesCAARTes TM trial. Its MuSK-CAART product candidate is designed to treat a subset of patients with MG, targeting autoreactive B cells.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
Cabaletta Bio (CABA) Shares Surge 11% Following Insider Purchases
- Insider Purchases: Cabaletta Bio's General Counsel, Michael Gerard, purchased 6,600 shares on January 21, 2026, totaling $14,979, indicating strong confidence in the company's future prospects.
- CMO Acquisition: Chief Medical Officer Chang David J. acquired 8,800 shares at an average price of $2.26 per share, reflecting executive recognition of the company's value and optimism about future performance.
- President's Stake: President of Science & Technology, Binder Gwendolyn, bought 11,312 shares at an average price of $2.1891, bringing total ownership to 31,312 shares, which further bolsters market confidence in the company's outlook.
- Market Reaction: Following the insider purchases, Cabaletta Bio's shares surged 11% on Thursday, reflecting investor optimism regarding the company's future developments.
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