Avidity Biosciences Enters Merger Agreement with Novartis
In a regulatory filing, Avidity Biosciences (RNA) noted that as previously disclosed, the company entered into an Agreement and Plan of Merger, dated as of October 25, 2025, with Novartis AG (NVS). On December 17, the FTC granted a request for the early termination of the waiting period under the HSR Act. "The expiration of the waiting period under the HSR Act satisfies one of the conditions to the consummation of the Transactions. The consummation of the Transactions remains subject to completion of the separation of Atrium Therapeutics, Inc. from the Company and the satisfaction or waiver of other customary closing conditions as described in the preliminary proxy statement filed by the Company with the SEC, as amended," the filing stated.
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Akeso's Ivonescimab Selected as Key Drug for 2026
- Industry Recognition: Akeso's ivonescimab has been included in FirstWord Pharma's list of 20 key drugs that will shape the global pharmaceutical industry in 2026, highlighting its significant role in innovative drug development and likely boosting the company's international recognition and competitiveness.
- Unique Advantage: As the only drug on the list originating from a Chinese innovative pharmaceutical company, ivonescimab's inclusion not only showcases China's rise in the global pharmaceutical sector but may also attract more investor interest in Akeso's R&D potential and market outlook.
- Global Strategy: Akeso is committed to its global

Trump Administration Launches Medicare Drug Price Negotiations
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- Spending Overview: According to the Centers for Medicare and Medicaid Services, approximately 1.8 million beneficiaries utilized these medications between 2024 and 2025, accounting for about $27 billion in spending, highlighting the significance of Medicare expenditures in drug price negotiations.
- Pharmaceutical Impact Assessment: Analysts indicate that for 14 of the drugs, only Gilead's Biktarvy significantly impacts the company's estimated 2027 global sales, representing around 8%, while other drugs' Medicare revenue exposure is limited to 0% to 3%, suggesting minimal overall revenue impact for pharmaceutical companies.
- Kaiser Settlement on Fraud: Kaiser Permanente has agreed to a historic $556 million settlement over Medicare Advantage fraud allegations, reflecting the government's stringent enforcement stance on Medicare fraud, which could have far-reaching implications for the industry.









