Aptevo Therapeutics Announces 1-for-18 Reverse Stock Split, Shares Hit All-Time Low
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 26 2025
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Source: Benzinga
- Reverse Stock Split Announcement: Aptevo Therapeutics has announced a 1-for-18 reverse stock split effective December 29, converting every 18 shares into one, aimed at boosting share price to meet listing requirements, yet this move has not prevented the stock from hitting an all-time low.
- Shareholder Approval: The reverse split was approved at the annual shareholder meeting in July, with the board confirming the final ratio in mid-December, demonstrating the company's commitment to structural adjustments with shareholder backing.
- Deteriorating Financial Performance: Aptevo recently reported a quarterly loss of $2.23 per share, exceeding analyst expectations of $2.09, with net losses increasing year-over-year from $5.1 million to $7.5 million, indicating heightened financial pressure on the company.
- Stock Price Decline: Following the announcement, Aptevo shares plummeted by 44.08%, trading at $0.5176, positioned at the lower end of its 52-week range, reflecting market pessimism regarding the company's future prospects.
Analyst Views on APVO
About APVO
Aptevo Therapeutics Inc. is a clinical-stage biotechnology company focused on developing novel bispecific immunotherapies for the treatment of cancer. The Company has two clinical candidates: Mipletamig and ALG.APV-527. Mipletamig is being evaluated in RAINIER, a two-part Phase 1b/2 trial for the treatment of frontline acute myeloid leukemia in combination with standard-of-care venetoclax + azacitidine. Mipletamig has received orphan drug designation for AML according to the Orphan Drug Act. ALG.APV-527, a bispecific conditional 4-1BB agonist, only active upon simultaneous binding to 4-1BB and 5T4, is being co-developed with Alligator Bioscience and is being evaluated in a Phase 1 clinical trial for the treatment of multiple solid tumor types likely to express 5T4. The Company has three pre-clinical candidates with different mechanisms of action designed to target a range of solid tumors. All pipeline candidates are created from two proprietary platforms, ADAPTIR and ADAPTIR-FLEX.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
