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APVO Overview

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$
0.000
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0.000(0.000%)Aft-market
ET
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0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
4.550
Open
4.500
VWAP
4.32
Vol
82.75K
Mkt Cap
5.05M
Low
4.140
Amount
357.46K
EV/EBITDA(TTM)
--
Total Shares
1.18M
EV
-16.57M
EV/OCF(TTM)
--
P/S(TTM)
--
Aptevo Therapeutics Inc. is a clinical-stage biotechnology company focused on developing novel bispecific immunotherapies for the treatment of cancer. The Company has two clinical candidates: Mipletamig and ALG.APV-527. Mipletamig is being evaluated in RAINIER, a two-part Phase 1b/2 trial for the treatment of frontline acute myeloid leukemia in combination with standard-of-care venetoclax + azacitidine. Mipletamig has received orphan drug designation for AML according to the Orphan Drug Act. ALG.APV-527, a bispecific conditional 4-1BB agonist, only active upon simultaneous binding to 4-1BB and 5T4, is being co-developed with Alligator Bioscience and is being evaluated in a Phase 1 clinical trial for the treatment of multiple solid tumor types likely to express 5T4. The Company has three pre-clinical candidates with different mechanisms of action designed to target a range of solid tumors. All pipeline candidates are created from two proprietary platforms, ADAPTIR and ADAPTIR-FLEX.
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Events Timeline

(ET)
2026-03-26
08:20:00
Aptevo Ends 2025 with $21.6 Million in Cash
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2026-03-26
08:20:00
Marvin White Says 2025 Sees Meaningful Progress in Clinical Programs
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2026-03-10 (ET)
2026-03-10
08:50:00
Aptevo Announces New mipletamig Data with 86% Clinical Benefit Rate
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2026-02-03 (ET)
2026-02-03
08:50:00
Aptevo Therapeutics Announces Executive Leadership Transitions to Support Strategic Objectives
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2026-01-28 (ET)
2026-01-28
16:10:00
Aptevo Therapeutics Files to Sell 7.075M Shares of Common Stock
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2026-01-09 (ET)
2026-01-09
08:20:00
Aptevo Therapeutics Enters $60M Credit Agreement with Yorkville Advisors
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2025-12-29 (ET)
2025-12-29
20:00:00
Aptevo Therapeutics Trading Halted, News Pending
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2025-12-09 (ET)
2025-12-09
08:30:00
Aptevo Presents Preliminary Results of mipletamig Study
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News

seekingalpha
9.5
03-26seekingalpha
Aptevo Therapeutics Reports FY GAAP EPS of -$87.27
  • Financial Performance: Aptevo Therapeutics reported a FY GAAP EPS of -$87.27, indicating significant financial challenges that could negatively impact investor confidence and stock performance.
  • Cash Position: As of the end of FY 2025, Aptevo's cash and cash equivalents stood at $21.6 million, a substantial increase from $8.7 million at December 31, 2024, suggesting improved cash management that supports operations into Q4 2026.
  • Reverse Stock Split: The company announced a 1-for-18 reverse stock split aimed at boosting its stock price, which may attract more investor interest, although it still faces challenges in achieving profitability in the near term.
  • Future Outlook: Despite the current financial difficulties, Aptevo expects its existing resources to sustain operations through Q4 2026, demonstrating resilience and potential for continued operation amid adversity.
seekingalpha
5.0
02-03seekingalpha
Aptevo Therapeutics Announces Executive Changes
  • CEO Retirement Announcement: Aptevo Therapeutics' CEO Marvin White will retire on April 1, 2026, transitioning to executive chair, which signifies a major leadership shift that could impact the company's strategic direction and investor confidence.
  • New CEO Appointment: Chief Operating Officer Jeff Lamothe will be appointed as the new President and CEO, joining the board, and this appointment is expected to bring fresh management perspectives and operational efficiencies that could drive future growth.
  • Board Structure Change: John E. Niederhuber will move from chairman to lead independent director, aiming to enhance corporate governance and improve the board's independence and decision-making capabilities, which may positively influence the company's long-term strategy.
  • Reverse Stock Split: Aptevo Therapeutics announced a 1-for-18 reverse stock split, aimed at increasing the share price to improve market perception and attract more investor interest, potentially enhancing the company's financing capabilities.
NASDAQ.COM
2.0
2025-12-29NASDAQ.COM
Aptevo (APVO) Implements 1-for-18 Reverse Stock Split, Reducing Shares to 1 Million
  • Reverse Stock Split Plan: Aptevo Therapeutics is set to implement a 1-for-18 reverse stock split on December 29, 2025, reducing outstanding shares from approximately 18 million to about 1 million, aimed at increasing the share price to meet Nasdaq listing requirements.
  • Market Reaction: Prior to the reverse split, APVO shares traded between $0.50 and $109.8 over the past year, closing at $0.60, down 34.73% from the previous day, indicating market concerns regarding the company's outlook.
  • Historical Split Record: This marks Aptevo's second reverse stock split in 2025, following a 1-for-20 split that took effect on May 27, reflecting the company's ongoing efforts in stock price management.
  • Shareholder Impact: The reverse split will automatically convert every 18 shares of common stock into 1 share, while the par value remains at $0.001, significantly reducing shareholders' equity and potentially affecting investor confidence and future fundraising capabilities.
Benzinga
2.0
2025-12-26Benzinga
Aptevo Therapeutics Announces 1-for-18 Reverse Stock Split, Shares Plunge 38.4%
  • Reverse Stock Split Announcement: Aptevo Therapeutics has announced a 1-for-18 reverse stock split effective December 29, converting every 18 shares into one, which has led to a significant 38.4% drop in share price to $0.57, indicating a negative market reaction despite prior shareholder approval in July.
  • Severe Market Reaction: Following the reverse stock split announcement, Aptevo's shares plummeted sharply during Friday's session, reflecting investor concerns about the company's future prospects, which could adversely affect its financing capabilities and market confidence.
  • Shareholder Approval Context: The final ratio for the reverse split was approved by the board in mid-December, despite having received shareholder support at the July annual meeting, yet the market's response raises questions about the company's governance and strategic direction.
  • Industry Impact: The sharp decline in Aptevo's stock price may affect its competitive position in the biopharmaceutical sector, particularly regarding financing and partnership opportunities, as investors may reassess its investment value.
Benzinga
2.0
2025-12-26Benzinga
Aptevo Therapeutics Announces 1-for-18 Reverse Stock Split, Shares Hit All-Time Low
  • Reverse Stock Split Announcement: Aptevo Therapeutics has announced a 1-for-18 reverse stock split effective December 29, converting every 18 shares into one, aimed at boosting share price to meet listing requirements, yet this move has not prevented the stock from hitting an all-time low.
  • Shareholder Approval: The reverse split was approved at the annual shareholder meeting in July, with the board confirming the final ratio in mid-December, demonstrating the company's commitment to structural adjustments with shareholder backing.
  • Deteriorating Financial Performance: Aptevo recently reported a quarterly loss of $2.23 per share, exceeding analyst expectations of $2.09, with net losses increasing year-over-year from $5.1 million to $7.5 million, indicating heightened financial pressure on the company.
  • Stock Price Decline: Following the announcement, Aptevo shares plummeted by 44.08%, trading at $0.5176, positioned at the lower end of its 52-week range, reflecting market pessimism regarding the company's future prospects.
Benzinga
9.5
2025-12-26Benzinga
Biohaven Reports Phase 2 Study Failure for BHV-7000, Stock Drops
  • Study Results Disappoint: Biohaven Ltd. (NYSE:BHVN) reported on Friday that its Phase 2 trial for BHV-7000 targeting major depressive disorder failed to meet its primary endpoint, resulting in a 10.4% drop in stock price, reflecting market concerns over the drug's development prospects.
  • Market Volatility: On the same day, industrial stocks fell by 0.2%, indicating uncertainty in the economic outlook, which could impact investor confidence and future capital flows.
  • Diverse Stock Performance: While Biohaven's stock declined, shares of Davis Commodities Ltd. (NASDAQ:DTCK) surged by 105.6% following the release of its financial results, highlighting a divergence in market reactions to different companies.
  • Overall Market Dynamics: The Dow Jones index fell by 0.1%, while the NASDAQ and S&P 500 indices rose by 0.12% and 0.11%, respectively, suggesting a complex market sentiment as investors navigate between sectors.

Valuation Metrics

The current forward P/E ratio for Aptevo Therapeutics Inc (APVO.O) is -0.20, compared to its 5-year average forward P/E of -0.55. For a more detailed relative valuation and DCF analysis to assess Aptevo Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-0.55
Current PE
-0.20
Overvalued PE
1.42
Undervalued PE
-2.52

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.00
Undervalued EV/EBITDA
0.00

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
2.40
Current PS
0.00
Overvalued PS
8.33
Undervalued PS
-3.54

Financials

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Frequently Asked Questions

What is Aptevo Therapeutics Inc (APVO) stock price today?

The current price of APVO is 4.27 USD — it has decreased -5.32

What is Aptevo Therapeutics Inc (APVO)'s business?

Aptevo Therapeutics Inc. is a clinical-stage biotechnology company focused on developing novel bispecific immunotherapies for the treatment of cancer. The Company has two clinical candidates: Mipletamig and ALG.APV-527. Mipletamig is being evaluated in RAINIER, a two-part Phase 1b/2 trial for the treatment of frontline acute myeloid leukemia in combination with standard-of-care venetoclax + azacitidine. Mipletamig has received orphan drug designation for AML according to the Orphan Drug Act. ALG.APV-527, a bispecific conditional 4-1BB agonist, only active upon simultaneous binding to 4-1BB and 5T4, is being co-developed with Alligator Bioscience and is being evaluated in a Phase 1 clinical trial for the treatment of multiple solid tumor types likely to express 5T4. The Company has three pre-clinical candidates with different mechanisms of action designed to target a range of solid tumors. All pipeline candidates are created from two proprietary platforms, ADAPTIR and ADAPTIR-FLEX.

What is the price predicton of APVO Stock?

Wall Street analysts forecast APVO stock price to fall over the next 12 months. According to Wall Street analysts, the average 1-year price target for APVO is USD with a low forecast of USD and a high forecast of USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Aptevo Therapeutics Inc (APVO)'s revenue for the last quarter?

Aptevo Therapeutics Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Aptevo Therapeutics Inc (APVO)'s earnings per share (EPS) for the last quarter?

Aptevo Therapeutics Inc. EPS for the last quarter amounts to -6.23 USD, decreased -100.00

How many employees does Aptevo Therapeutics Inc (APVO). have?

Aptevo Therapeutics Inc (APVO) has 37 emplpoyees as of March 31 2026.

What is Aptevo Therapeutics Inc (APVO) market cap?

Today APVO has the market capitalization of 5.05M USD.