Aptevo (APVO) Implements 1-for-18 Reverse Stock Split, Reducing Shares to 1 Million
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 29 2025
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Source: NASDAQ.COM
- Reverse Stock Split Plan: Aptevo Therapeutics is set to implement a 1-for-18 reverse stock split on December 29, 2025, reducing outstanding shares from approximately 18 million to about 1 million, aimed at increasing the share price to meet Nasdaq listing requirements.
- Market Reaction: Prior to the reverse split, APVO shares traded between $0.50 and $109.8 over the past year, closing at $0.60, down 34.73% from the previous day, indicating market concerns regarding the company's outlook.
- Historical Split Record: This marks Aptevo's second reverse stock split in 2025, following a 1-for-20 split that took effect on May 27, reflecting the company's ongoing efforts in stock price management.
- Shareholder Impact: The reverse split will automatically convert every 18 shares of common stock into 1 share, while the par value remains at $0.001, significantly reducing shareholders' equity and potentially affecting investor confidence and future fundraising capabilities.
Analyst Views on APVO
About APVO
Aptevo Therapeutics Inc. is a clinical-stage biotechnology company focused on developing novel bispecific immunotherapies for the treatment of cancer. The Company has two clinical candidates: Mipletamig and ALG.APV-527. Mipletamig is being evaluated in RAINIER, a two-part Phase 1b/2 trial for the treatment of frontline acute myeloid leukemia in combination with standard-of-care venetoclax + azacitidine. Mipletamig has received orphan drug designation for AML according to the Orphan Drug Act. ALG.APV-527, a bispecific conditional 4-1BB agonist, only active upon simultaneous binding to 4-1BB and 5T4, is being co-developed with Alligator Bioscience and is being evaluated in a Phase 1 clinical trial for the treatment of multiple solid tumor types likely to express 5T4. The Company has three pre-clinical candidates with different mechanisms of action designed to target a range of solid tumors. All pipeline candidates are created from two proprietary platforms, ADAPTIR and ADAPTIR-FLEX.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
