Enliven Therapeutics Inc's stock surged by 54.69% as it crossed above the 20-day SMA, reflecting strong investor interest amid mixed market conditions.
This significant price movement is attributed to the announcement that ELVN-001 achieved a 69% major molecular response rate at 24 weeks in its Phase 1b trial for chronic myeloid leukemia, indicating its potential as a leading treatment option. Additionally, the appointment of Scott Garland to the Board, aimed at advancing the commercialization of ELVN-001, further bolstered investor confidence in the company's strategic direction.
The positive trial results and leadership changes position Enliven Therapeutics favorably in the competitive biopharma landscape, suggesting a strong outlook for the future development and market introduction of ELVN-001.
Wall Street analysts forecast ELVN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ELVN is 40.20 USD with a low forecast of 35.00 USD and a high forecast of 48.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
6 Analyst Rating
Wall Street analysts forecast ELVN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ELVN is 40.20 USD with a low forecast of 35.00 USD and a high forecast of 48.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 26.160
Low
35.00
Averages
40.20
High
48.00
Current: 26.160
Low
35.00
Averages
40.20
High
48.00
H.C. Wainwright
H.C. Wainwright
NULL -> Buy
maintain
$40 -> $48
2025-07-02
Reason
H.C. Wainwright
H.C. Wainwright
Price Target
$40 -> $48
AI Analysis
2025-07-02
maintain
NULL -> Buy
Reason
H.C. Wainwright raised the firm's price target on Enliven to $48 from $40 and keeps a Buy rating on the shares after the company presented updated results from the Phase 1a/1b ENABLE trial at EHA 2025. Following the presentation at the medical meeting, the firm contends that ELVN-001 could become "the go-to agent" in chronic myelogenous leukemia.
Goldman Sachs
Salveen Richter
NULL -> Buy
upgrade
$37
2025-06-17
Reason
Goldman Sachs
Salveen Richter
Price Target
$37
2025-06-17
upgrade
NULL -> Buy
Reason
Goldman Sachs analyst Salveen Richter assigned of Enliven with a Buy rating and $37 price target from a previous Early-Stage Biotech designation. The firm cites the company's continued positive Phase 1 data and the announcement of a planned Phase 3 initiation in 2026 for tyrosine kinase inhibitor ELVN-001 in chronic myeloid leukemia for the Buy rating. ELVN-001 remains well-tolerated, with no increased cardiovascular toxicity, and the data supports the potential for once daily dosing without the need for fasting and low drug-drug interactions, the analyst tells investors in a research note.
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Baird
Colleen Kusy
Outperform
maintain
$40 -> $52
2025-06-17
Reason
Baird
Colleen Kusy
Price Target
$40 -> $52
2025-06-17
maintain
Outperform
Reason
Baird analyst Colleen Kusy raised the firm's price target on Enliven to $52 from $40 and keeps an Outperform rating on the shares. The firm updated its model as its ELVN-001 data continues to show improvement which supports its compelling profile.
JonesResearch
Soumit Roy
Buy
downgrade
$36 -> $27
2025-05-16
Reason
JonesResearch
Soumit Roy
Price Target
$36 -> $27
2025-05-16
downgrade
Buy
Reason
JonesResearch analyst Soumit Roy lowered the firm's price target on Enliven to $27 from $36 and keeps a Buy rating on the shares. The company's abstract from the Phase 1 late line chronic myeloid leukemia trial with ELVN-001 "was met with a lukewarm initial stock reaction that weakened over time," the analyst tells investors in a research note. The firm says that even though ELVN-001 showed efficacy and safety profile inline with the September 2024 update with two-times the patient population, the market treated the stock with a sell on news approach. Jones sees ELVN-001 performing at least inline with Novartis' Scemblix.
About ELVN
Enliven Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on the discovery and development of small molecule inhibitors to help patients with cancer. It is advancing two parallel lead product candidates, ELVN-001 and ELVN-002, and pursuing several additional research stage opportunities that align with its development approach. Its first product candidate, ELVN-001, is a potent, highly selective, small molecule kinase inhibitor designed to specifically target the breakpoint cluster region-Abelson (BCR-ABL) gene fusion, the oncogenic driver for patients with chronic myeloid leukemia. Its second product candidate, ELVN-002, is a potent, highly selective, central nervous system penetrant and irreversible human epidermal growth factor receptor 2 (HER2) inhibitor with activity against wild type HER2 and various HER2 mutations. ELVN-002 is designed to inhibit wild type HER2 and key mutations of HER2, while sparing wild-type EGFR and avoiding EGFR-related toxicities.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
