Amgen Reports Strong Q4 Results Exceeding Expectations
Amgen's stock rose 3.00% as it reached a 52-week high, reflecting strong investor confidence following its recent earnings report.
The company's Q4 total revenue increased by 9% year-over-year to $9.9 billion, surpassing analyst expectations of $9.5 billion, driven by a 7% rise in drug sales. Adjusted earnings per share remained stable at $5.29, slightly above the expected $4.73, and Amgen's 2026 outlook projects adjusted EPS between $21.60 and $23.00, indicating robust future growth potential.
These results highlight Amgen's competitive position in the market, particularly with strong sales of its cholesterol drug Repatha, which surged by 44% to $870 million, despite a slight decline in sales for Tepezza. Overall, the earnings report has bolstered market confidence in Amgen's growth trajectory.
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- Stock Performance: Amgen (AMGN) rose by 1.69% to $355.30 in the latest trading session, outperforming the S&P 500's daily gain of 1.2%, indicating its relative strength in the market.
- Earnings Forecast: The company is expected to report an EPS of $4.76 in its earnings release on April 30, 2026, representing a 2.86% decline from the same quarter last year, which may impact investor confidence.
- Revenue Expectations: The consensus estimate forecasts Amgen's revenue to reach $8.5 billion, reflecting a 4.3% year-over-year growth, indicating some resilience in revenue growth despite profit pressures.
- Valuation Analysis: Amgen's forward P/E ratio stands at 15.75, below the industry average of 20.76, suggesting that its stock may be undervalued and attracting value investors, while a PEG ratio of 3.65 reflects expectations for future earnings growth.
- Global Clinical Trial Collaboration: On April 1, Zai Lab entered into a global clinical trial collaboration with Amgen to evaluate a combination therapy for extensive-stage small cell lung cancer, showcasing strategic synergy in oncology treatment between the two companies.
- Dual-Targeting Strategy: The study will combine Zai Lab's zocilurtatug pelitecan with Amgen's IMDELLTRA, aiming to enhance clinical responses and address potential resistance pathways through complementary mechanisms, thereby improving survival chances for patients.
- Clinical Trial Progress: Zocilurtatug pelitecan has demonstrated a high response rate and a tolerable safety profile in heavily pretreated SCLC patients, indicating its therapeutic potential, especially with FDA orphan drug and fast track designations.
- New Treatment Paradigm: By combining the first-ever approved DLL3-targeting bispecific therapy, Zai Lab and Amgen aim to establish a new treatment paradigm for one of the most aggressive and lethal forms of solid tumors.
- New Drug Approval Outlook: Teva's New Drug Application for long-acting schizophrenia drug olanzapine has been accepted by the FDA, and if approved, it is expected to significantly enhance patient adherence, driving sales growth and becoming the company's most meaningful catalyst.
- Specialty Drug Sales Surge: Teva's Austedo generated $2.26 billion in sales in 2025, marking a 34% year-over-year increase, with expectations to reach between $2.4 billion and $2.55 billion in 2026, showcasing strong momentum in the specialty drug sector.
- Biosimilar Market Expansion: Teva plans to launch six new biosimilars in 2026 and 2027, potentially competing with Amgen and Johnson & Johnson, which will further solidify its position as the second-largest player in the biosimilar market.
- Investor Confidence Boost: Analysts are optimistic about Teva's future, with 12 out of 15 analysts rating the stock as a
- FDA Approval Catalyst: Teva's long-acting olanzapine injectable suspension NDA has been accepted by the FDA, with a decision expected later this year; approval could significantly enhance patient adherence, with combined annual sales with Uzedy projected to exceed $2 billion.
- Specialty Drug Sales Surge: Teva's specialty drug Austedo generated $2.26 billion in sales in 2025, a 34% year-over-year increase, with expectations for 2026 sales to rise between $2.4 billion and $2.55 billion, reflecting strong market demand and competitive positioning in the specialty drug sector.
- Biosimilar Expansion: Teva plans to launch six new biosimilars in 2026 and 2027, further solidifying its position as the second-largest player in the biosimilar market, with anticipated competition against giants like Amgen and Johnson & Johnson, driving future revenue growth.
- Market Risk Factors: Despite several catalysts propelling stock price growth, a market crash or significant pipeline issues could derail Teva's momentum; however, the company's pipeline is relatively de-risked, and with a forward P/E of only 11.7, it presents a compelling value investment opportunity.

- Drug Approval: BeOne Medicines announced that its bispecific T-cell engager tarlatamab, developed in partnership with Amgen, received conditional approval in China as a second-line treatment for extensive-stage small cell lung cancer, marking a significant milestone for the company in the Chinese market.
- Market Potential: Approximately 160,000 patients are diagnosed with small cell lung cancer in China each year, accounting for nearly 15% of global lung cancer cases, providing a substantial market opportunity for tarlatamab, especially given the limited efficacy of existing treatments.
- Treatment Need: Despite platinum-based chemotherapy being the main first-line therapy, the majority of small cell lung cancer patients experience disease progression within six months, thus the approval of tarlatamab offers a new treatment option that could potentially improve survival rates and quality of life for these patients.
- Collaboration Background: BeOne Medicines has been developing tarlatamab in Mainland China under a licensing agreement with Amgen since 2019, and this approval not only strengthens the partnership between the two companies but also lays a foundation for BeOne's further development in the biopharmaceutical sector.
- Price Range Analysis: TQQQ ETF's 52-week low is $20.12 per share, with a high of $60.685, while the last trade was at $47.37, indicating significant volatility and shifts in investor sentiment within the current market.
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