Opaleye Management Sells Liquidia Shares Worth $5.12 Million
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 6 days ago
0mins
Should l Buy LQDA?
Source: Fool
- Share Sale Details: Opaleye Management disclosed in an SEC filing on February 17, 2026, that it sold 180,000 shares of Liquidia, valued at approximately $5.12 million, indicating a strategic reduction in its holdings.
- Holding Proportion Change: Following this transaction, Opaleye's stake in Liquidia decreased to 2.435 million shares, representing 11.21% of its reportable AUM, reflecting a cautious outlook on the company's future performance.
- Market Performance Analysis: As of February 17, 2026, Liquidia's stock was priced at $33.84, marking a 105.7% increase over the past year, significantly outperforming the S&P 500 by 97 percentage points, showcasing its strong growth potential in the biopharmaceutical sector.
- Company Overview: Liquidia focuses on innovative therapies for pulmonary arterial hypertension, primarily generating revenue through the development and commercialization of proprietary and generic therapies, demonstrating its competitive advantage in a highly regulated pharmaceutical industry.
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Analyst Views on LQDA
Wall Street analysts forecast LQDA stock price to rise
8 Analyst Rating
8 Buy
0 Hold
0 Sell
Strong Buy
Current: 35.870
Low
31.00
Averages
47.50
High
67.00
Current: 35.870
Low
31.00
Averages
47.50
High
67.00
About LQDA
Liquidia Corporation is a biopharmaceutical company. The Company is focused on the development, manufacture and commercialization of products that address unmet patient needs, with a focus directed towards rare cardiopulmonary diseases, such as pulmonaryarterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PH-ILD). The Company operate through its wholly owned operating subsidiaries, Liquidia Technologies, Inc. and Liquidia PAH, LLC. Its proprietary PRINT technology is a particle engineering platform, which enable precise production of uniform drug particles. Its lead product candidate is YUTREPIA for the treatment of PAH and PH-ILD. YUTREPIA is an inhaled dry powder formulation of treprostinil designed with PRINT to improve the therapeutic profile of treprostinil by enhancing deep lung delivery while using a convenient, dry-powder inhaler (DPI) and by achieving higher dose levels than the labeled doses of current inhaled therapies.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
- Put Option Appeal: The current bid for the $35.00 put option is $9.80, and if an investor sells this contract, they commit to buying the stock at $35.00, effectively lowering their cost basis to $25.20, which represents a 4% discount from the current price of $36.65, making it attractive for those interested in LQDA.
- Return Potential: Should the put option expire worthless, the premium would yield a 28% return on cash commitment, or 36.11% annualized, making this investment strategy particularly appealing in the current market context.
- Call Option Returns: The $40.00 call option has a current bid of $10.10, and if an investor buys LQDA shares at $36.65 and sells this call, they could achieve a total return of 36.70% if the stock is called away at expiration, providing an additional revenue opportunity.
- Risk Assessment: Current data indicates a 35% chance that the $40.00 call option will expire worthless, allowing investors to retain both their shares and the premium collected, thereby enhancing the safety and return potential of their investment.
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- Liquidia Options Volume: Liquidia Corp (Ticker: LQDA) experienced an options trading volume of 9,692 contracts today, equating to approximately 969,200 shares, which represents about 48.1% of its average daily trading volume of 2 million shares over the past month, indicating heightened market interest in its future performance.
- High Call Option Activity: Among LQDA options, the $47.50 strike call option expiring on January 21, 2028, has seen particularly high activity with 3,100 contracts traded today, representing around 310,000 underlying shares, suggesting increased investor expectations for a price rise.
- Dianthus Options Trading: Dianthus Therapeutics Inc (Ticker: DNTH) recorded an options trading volume of 3,379 contracts today, equivalent to approximately 337,900 shares, which is about 48% of its average daily trading volume of 704,415 shares over the past month, reflecting market interest in its potential volatility.
- High Put Option Activity: The $50 strike put option for DNTH, expiring on March 20, 2026, has seen 1,659 contracts traded today, representing approximately 165,900 underlying shares, indicating investor concern regarding potential downside risks.
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- Sales Growth: YUTREPIA achieved $148.3 million in net product sales for 2025, with $90.1 million in Q4 alone, reflecting a robust 74% growth over Q3 2025, indicating strong market demand and sales momentum.
- Profitability Improvement: The company reported $27.3 million in non-GAAP adjusted EBITDA and $14.6 million in net income for Q4, marking the second consecutive quarter of profitability growth, showcasing success in cost control and market expansion.
- Market Share Expansion: YUTREPIA's market share increased from 10% in Q3 2025 to 17% in Q4, demonstrating significant progress in a competitive landscape and further solidifying the company's market position.
- Future Development Plans: Liquidia plans to initiate multiple new studies in 2026 aimed at expanding product indications and further clinical validation, with management expressing strong confidence in achieving a $1 billion revenue target by 2027, reflecting a robust belief in future growth.
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- Financial Highlights: Liquidia reported Q4 revenue of $92.02 million, exceeding analysts' expectations of $83.70 million, although its earnings per share (EPS) of $0.15 fell short of the $0.19 estimate, indicating strong revenue growth despite EPS challenges.
- Product Revenue Surge: The revenue from YUTREPIA is projected to reach approximately $148.3 million in 2025, with about $90.1 million generated in Q4 alone, showcasing significant early traction in the drug's commercial rollout.
- Positive Market Reaction: Following the earnings report, Liquidia's stock traded over 6% higher in Thursday's premarket, reflecting investor optimism regarding the company's growth potential.
- Strategic Implications: While EPS did not meet expectations, the robust revenue growth and favorable market response suggest that Liquidia is on a promising path in the commercialization of its respiratory drug, potentially laying the groundwork for sustained future growth.
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- Earnings Performance: Liquidia reported a Q4 GAAP EPS of $0.15, missing expectations by $0.05, indicating potential pressure on profitability that may affect investor confidence.
- Revenue Surge: The company achieved Q4 revenue of $92.02 million, reflecting a staggering 3051.4% year-over-year increase, surpassing market expectations by $4.53 million, demonstrating strong product demand and ongoing market share expansion.
- Market Outlook: Liquidia is poised for robust performance in the coming years, particularly with a strong outlook for 2026, highlighting its competitive advantages in specific markets.
- Industry Dynamics: Despite Liquidia's stock facing pressure due to United Therapeutics considering a new treprostinil formulation, the company is actively pursuing special situation gains and long-term growth opportunities.
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- Sales Growth: In 2025, YUTREPIA® achieved net product sales of $148.3 million, with fourth-quarter sales reaching $90.1 million, indicating strong market demand and product acceptance, thereby solidifying Liquidia's position in the specialty drug market.
- Profitability Improvement: The company recorded a net income of $14.6 million in the fourth quarter of 2025, marking its second consecutive profitable quarter, demonstrating rapid financial stability post-launch and enhancing its capacity for future investments and expansions.
- Strong Cash Position: As of December 31, 2025, Liquidia's cash and cash equivalents totaled $190.7 million, an increase of $33.2 million from the third quarter, ensuring financial flexibility for future R&D and marketing initiatives.
- Prescription Growth: Since its launch in June 2025, YUTREPIA has received over 3,600 unique prescriptions and treated more than 2,900 patients, with a prescription-to-start conversion rate maintained above 85%, reflecting high recognition and trust from both physicians and patients.
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