Gilead and Arcus suspend advanced trial for anti-TIGIT cancer treatment
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 12 2025
0mins
Should l Buy GILD?
Source: SeekingAlpha
Discontinuation of Trials: Arcus Biosciences (RCUS) saw a ~14% drop in premarket trading after announcing the discontinuation of its Phase 3 trial for the anti-TIGIT therapy domvanalimab in gastric and esophageal cancers, as it did not improve overall survival compared to the control group.
Focus Shift to Other Drug: Following the trial setback, Arcus will also halt its Phase 2 EDGE-Gastric studies and redirect resources towards casdatifan, another cancer drug, with multiple data readouts and study initiations anticipated next year.
Financial Position: The company reported approximately $1 billion in cash and investments, which is projected to sustain its operations through the second half of 2028.
Market Implications: The news has implications for other developers of anti-TIGIT therapies, such as Compugen (CGEN), as the market reacts to the discontinuation of the trial.
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Analyst Views on GILD
Wall Street analysts forecast GILD stock price to fall
19 Analyst Rating
16 Buy
3 Hold
0 Sell
Strong Buy
Current: 151.810
Low
105.00
Averages
137.88
High
154.00
Current: 151.810
Low
105.00
Averages
137.88
High
154.00
About GILD
Gilead Sciences, Inc. is a biopharmaceutical company. It is engaged in advancing medicines to prevent and treat life-threatening diseases, including HIV, viral hepatitis, COVID-19, cancer, and inflammation. It is focused on discovering, developing, and delivering medicines to address unmet medical needs in virology, oncology, and other therapeutic areas. Its portfolio of marketed products includes Biktarvy, Genvoya, Descovy, Complera/Eviplera, Symtuza, Truvada, Stribild, Sunlenca, Epclusa, Vemlidy, Harvoni, Viread, Livdelzi, Veklury, Yescarta, Tecartus, Trodelvy, AmBisome, and Letairis. Its product candidates include Bulevirtide, Lenacapavir, Axicabtagene ciloleucel, Sacituzumab govitecan-hziy, and others. It also develops the HB-400 program and the HB-500 program. It develops therapies that are intended to provide functional cures for hepatitis B virus and human immunodeficiency virus-1. It has a cancer program, namely TREX1. It operates in more than 35 countries worldwide.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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