Genmab Reports $14.35 Billion in DARZALEX® Global Sales for 2025
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jan 21 2026
0mins
Should l Buy GMAB?
Source: Globenewswire
- Strong Sales Performance: Genmab announced that global net sales of DARZALEX® (daratumumab) reached $14.35 billion in 2025, with $8.27 billion from the U.S. and $6.09 billion from the rest of the world, indicating robust demand and growth potential for the drug in the global market.
- Royalty Revenue: Genmab's royalties from Johnson & Johnson (J&J) on worldwide net sales reinforce its market position in the antibody drug sector and provide stable funding for future research and development initiatives.
- Market Expansion Potential: With ongoing promotion of DARZALEX® and the development of new indications, Genmab is poised to further increase its market share in the coming years, particularly in the competitive landscape of global cancer treatment.
- Innovation-Driven Growth: Genmab is committed to improving the lives of cancer patients through innovative antibody medicines and will continue to advance its strong clinical pipeline, aiming to deliver transformative therapies and enhance its influence in the biotechnology industry.
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Analyst Views on GMAB
Wall Street analysts forecast GMAB stock price to rise
7 Analyst Rating
5 Buy
2 Hold
0 Sell
Moderate Buy
Current: 26.790
Low
26.00
Averages
38.50
High
48.00
Current: 26.790
Low
26.00
Averages
38.50
High
48.00
About GMAB
Genmab A/S is a Denmark-based international biotechnology company. It specializes in the creation and development of antibody therapeutics for the treatment of cancer. The Company is the creator of the approved antibodies: DARZALEX (daratumumab) for the treatment of certain multiple myeloma indications, Kesimpta for the treatment of adults with relapsing forms of multiple sclerosis, TEPEZZA (teprotumumab) for the treatment of thyroid eye disease and FASPRO, for the treatment of adult patients with certain multiple myeloma indications. The first approved Genmab created therapy Arzerra, approved for the treatment of certain chronic lymphocytic leukemia indications, is available in Japan and is also available in other territories via compassionate use or oncology access programs. Genmab develops a broad clinical and pre-clinical product pipeline, and owns four antibody technologies, DuoBody bispecific platform, HexaBody platform, DuoHexaBody platform & HexElect platform.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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- Company Overview: Genmab is an international biotechnology firm dedicated to improving the lives of cancer and serious disease patients through innovative antibody medicines, boasting over 25 years of experience and a diverse range of antibody therapeutic formats, showcasing its robust R&D capabilities.
- Clinical Pipeline Progress: Genmab is advancing a strong late-stage clinical pipeline aimed at delivering transformative medicines to patients, which not only enhances the company's market competitiveness but also lays the groundwork for future revenue growth.
- Global Presence: Headquartered in Copenhagen, Denmark, Genmab has an international footprint across North America, Europe, and Asia Pacific, reflecting its strategic implementation of a global strategy to capture growth opportunities in the global biopharmaceutical market.
See More
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- Strong Sales Performance: Genmab reported that its multiple myeloma therapy DARZALEX achieved worldwide net sales of $3.96 billion in Q1, with U.S. sales contributing $2.208 billion and international markets generating $1.756 billion, indicating robust global demand for the product.
- Positive Market Reaction: Genmab's stock traded approximately 2% higher during pre-market hours, reflecting investor optimism regarding the company's sales growth and further solidifying its market position in the biopharmaceutical sector.
- Product Diversification: The sales figures include both intravenous and subcutaneous formulations, with the latter marketed in the U.S. as DARZALEX FASPRO, demonstrating the company's innovation in product forms to meet diverse patient needs.
- Industry Context: Despite pressures on the healthcare sector due to disruptions in the Middle East, Genmab stands out among oversold healthcare stocks above $10 billion, showcasing its product resilience and competitive strength in the market.
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- Royalty Revenue: Genmab benefits from royalties on DARZALEX sales through its exclusive global licensing agreement with Johnson & Johnson, which not only provides a stable revenue stream but also strengthens its market position in the biopharmaceutical sector.
- Innovative Drug Development: Genmab is committed to improving the lives of cancer patients through innovative antibody medicines, showcasing its R&D capabilities and competitive edge in biotechnology, which is expected to drive future revenue growth.
- Global Market Presence: As an international biotechnology company, Genmab has established operations across North America, Europe, and Asia Pacific, and this global strategy enhances its market reach while providing ample opportunities for future expansion and growth.
See More
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- Clinical Trial Results: The RAINFOL™-01 trial demonstrated that the combination of Rina-S and bevacizumab was well-tolerated in 40 patients with advanced ovarian cancer, with no new safety signals, indicating potential for broader clinical treatment options.
- Adverse Event Analysis: Common treatment-emergent adverse events included nausea (80%), fatigue (67.5%), anemia (55%), and neutropenia (45%), providing critical safety data for future treatment regimens.
- Research Significance: Investigator Dr. Cara Mathews noted that the safety profile of Rina-S aligns with that of bevacizumab, potentially offering more effective disease control options for ovarian cancer patients, particularly in resistant cases.
- Future Development Directions: Genmab plans to further evaluate the efficacy of this combination therapy in the upcoming Phase 3 RAINFOL-04 trial, showcasing the company's ongoing commitment and innovative potential in ovarian cancer treatment.
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- Market Opportunity Analysis: Analysts highlight that CRB-701's application in head and neck cancer could present significant upside potential, especially given the limited treatment options currently available, likely attracting more investor interest.
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