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WVE Overview

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$
0.000
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0.000(0.000%)Aft-market
ET
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0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
7.290
Open
7.190
VWAP
7.19
Vol
2.55M
Mkt Cap
1.38B
Low
7.100
Amount
18.34M
EV/EBITDA(TTM)
--
Total Shares
192.40M
EV
836.86M
EV/OCF(TTM)
--
P/S(TTM)
17.80
Wave Life Sciences Ltd. is a biotechnology company focused on unlocking the broad potential of ribonucleic acid (RNA) medicines to transform human health. The Company’s RNA medicines platform, PRISM, combines multiple modalities, chemistry innovation and deep insights in human genetics to deliver scientific breakthroughs that treat both rare and common disorders. Its toolkit of RNA-targeting modalities includes editing, splicing, RNA interference and antisense silencing, providing Wave with unmatched capabilities for designing and sustainably delivering candidates that optimally address disease biology. The Company’s diversified pipeline includes clinical programs in alpha-1 antitrypsin deficiency, obesity, Duchenne muscular dystrophy, and Huntington’s disease, as well as several preclinical programs utilizing the Company’s broad RNA therapeutics toolkit. Its programs include WVE-006, SERPINA1 (AATD); WVE-007 (GalNAc), INHBE (Obesity); WVE-N531, Exon 53 (DMD), and WVE-003, mHTT (HD).
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Events Timeline

(ET)
2026-05-08
16:30:00
Dow Jones Slightly Up, Nasdaq Surges After Jobs Report
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2026-05-08
13:40:00
Trump Signs Plan to Fire FDA Commissioner Makary
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link
2026-04-28 (ET)
2026-04-28
07:40:00
Wave Life Sciences Reports Q1 Revenue of $38.25M
select
2026-04-21 (ET)
2026-04-21
16:10:00
Wave Life Sciences Seeks Singapore High Court Approval to Redomicile to the U.S.
select

News

seekingalpha
9.5
04-28seekingalpha
Wave Life Sciences Q1 Earnings Exceed Expectations
  • Strong Earnings Report: Wave Life Sciences reported a Q1 GAAP EPS of -$0.13, beating expectations by $0.19, indicating positive progress in financial performance.
  • Significant Revenue Growth: The company achieved revenue of $38.25 million, a 316.7% year-over-year increase, surpassing market expectations of $30.33 million, reflecting strong demand for its products.
  • Adequate Cash Reserves: As of March 31, 2026, Wave's cash and cash equivalents stood at $544.6 million, down from $602.1 million as of December 31, 2025, but still sufficient to fund operations into Q3 2028.
  • Future Potential: While current cash flow supports operations, potential milestone and other payments from the GSK collaboration are not included in the cash runway, which could provide additional funding for the company.
Newsfilter
9.5
04-28Newsfilter
Wave Life Sciences Reports Q1 2026 Financial Results and Business Updates
  • Clinical Trial Progress: The FDA has accepted the Phase 2a multidose trial of WVE-007, set to initiate in Q2 2026, aimed at assessing weight, body fat, and cardiometabolic health indicators in individuals with high BMI, showcasing the company's ongoing innovation in obesity treatment.
  • Strong Financial Position: As of March 31, 2026, Wave reported cash and cash equivalents of $544.6 million, expected to fund operations into Q3 2028, indicating robust financial management and future growth potential.
  • Increased R&D Investment: Research and development expenses for Q1 2026 reached $47.4 million, up from $40.6 million in the same period of 2025, reflecting the company's ongoing commitment to advancing RNA therapeutics.
  • Therapeutic Potential: Clinical data from WVE-006 in treating AATD demonstrate significant efficacy, with regulatory feedback on an accelerated approval pathway anticipated by mid-2026, further solidifying the company's market position in RNA editing.
Newsfilter
9.5
04-22Newsfilter
Wave Life Sciences to Host Q1 2026 Financial Results Call on April 28
  • Earnings Call Announcement: Wave Life Sciences will host a conference call on April 28, 2026, at 8:30 a.m. ET to review its Q1 2026 financial results and provide business updates, which is expected to impact investor confidence positively.
  • Investor Participation: Investors can join the call by visiting the 'Investor Events' section on the company's website, ensuring transparency and information sharing while enhancing engagement with stakeholders.
  • Company Overview: Wave Life Sciences focuses on RNA medicines, leveraging its PRISM® platform that combines multiple modalities and deep insights into human genetics to address both rare and common disorders, showcasing significant market potential.
  • Pipeline Summary: The company's pipeline includes clinical programs targeting obesity (WVE-007), alpha-1 antitrypsin deficiency (WVE-006), and PNPLA3 I148M liver disease (WVE-008), demonstrating its diverse and innovative capabilities in the RNA therapeutics space.
NASDAQ.COM
9.0
04-01NASDAQ.COM
Wave Life Sciences' Weight Loss Drug Fails Phase 1 Study
  • Disappointing Trial Results: Wave Life Sciences' weight loss drug WVE-007 only achieved a 1% reduction in body weight during its Phase 1 clinical trial, indicating a lack of competitiveness in the rapidly growing anti-obesity market, which led to a sharp decline in stock price.
  • Significant Fat Reduction: Despite limited weight loss, WVE-007 demonstrated a 5% reduction in total fat and a 14% reduction in visceral fat, suggesting potential for the drug in targeting the most dangerous fat type, which may support its further clinical trials.
  • Muscle Mass Preservation: The trial results revealed that while visceral fat decreased, waist circumference dropped by 3%, and lean mass increased by 2%, indicating that the drug could help patients lose harmful fat while maintaining muscle mass, addressing critical health concerns.
  • Future Challenges Ahead: Although WVE-007 shows promise in fat reduction, the company must still navigate Phase 2 and Phase 3 trials and faces risks of clinical or regulatory setbacks, necessitating careful evaluation of its above-average risk profile by investors.
Fool
9.0
04-01Fool
Wave Life Sciences Phase 1 Trial Results Disappoint Investors
  • Trial Results: Wave Life Sciences' WVE-007 showed only a 1% weight reduction in its Phase 1 trial, but reductions in total fat and visceral fat of 5% and 14% respectively indicate potential efficacy, despite the market's overly negative reaction.
  • Muscle Preservation Advantage: Unlike existing GLP-1 drugs, WVE-007 increased lean mass by 2% while reducing fat, which could provide a unique competitive edge in the weight-loss market, particularly for visceral fat treatment.
  • Market Risk Assessment: Although WVE-007 demonstrated some fat loss in Phase 1, the company must still navigate Phase 2 and 3 trials, facing clinical and regulatory risks that investors should carefully consider due to the stock's high-risk profile.
  • Investment Opportunity: Given the current stock price, despite uncertainties surrounding Wave Life Sciences, risk-tolerant investors might find it worthwhile to initiate a small position and gradually increase their stake as the company progresses.
NASDAQ.COM
2.0
04-01NASDAQ.COM
Wave Life Sciences Shares Surge 9.5% Amid Trading Volume Spike
  • Price Rebound: Wave Life Sciences shares surged 9.5% in the last trading session to close at $7.25, with trading volume significantly higher than usual, indicating market interest in its future performance despite a 52.2% decline over the past four weeks.
  • Earnings Expectations: The company is expected to report a quarterly loss of $0.34 per share, reflecting a year-over-year decline of 17.2%, while revenues are projected at $10.73 million, up 16.8%, suggesting potential growth despite challenges.
  • Earnings Estimate Revision: Over the past 30 days, the consensus EPS estimate for Wave Life Sciences has been revised 1.2% lower, which typically correlates with a lack of price appreciation, prompting investors to monitor whether the recent price jump can sustain itself.
  • Industry Context: Wave Life Sciences operates within the biomedical and genetics sector, currently holding a Zacks Rank of 3 (Hold), while its peer Sutro Biopharma has seen a 17.3% increase in share price over the past month, highlighting competitive dynamics within the industry.
Wall Street analysts forecast WVE stock price to rise
14 Analyst Rating
Wall Street analysts forecast WVE stock price to rise
14 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
21.00
Averages
33.00
High
50.00
Current: 0.000
sliders
Low
21.00
Averages
33.00
High
50.00
Citi
Samantha Semenkow
Buy
downgrade
$30 -> $24
AI Analysis
2026-05-04
Reason
Citi
Samantha Semenkow
Price Target
$30 -> $24
AI Analysis
2026-05-04
downgrade
Buy
Reason
Citi analyst Samantha Semenkow lowered the firm's price target on Wave Life Sciences to $24 from $30 and keeps a Buy rating on the shares.
Canaccord
Buy
downgrade
$52 -> $43
2026-04-30
Reason
Canaccord
Price Target
$52 -> $43
2026-04-30
downgrade
Buy
Reason
Canaccord lowered the firm's price target on Wave Life Sciences to $43 from $52 and keeps a Buy rating on the shares. The firm said headed into the next AATD update, focus remains on the amount of M- and total- AAT protein that can be produced with more and higher WVE-006 doses. Canaccord said they continue to think shares are trading at a significant discount following the last INHBE update/sell off.
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Valuation Metrics

The current forward P/E ratio for WAVE Life Sciences Ltd (WVE.O) is 0.00, compared to its 5-year average forward P/E of -5.26. For a more detailed relative valuation and DCF analysis to assess WAVE Life Sciences Ltd's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.26
Current PE
0.00
Overvalued PE
-1.83
Undervalued PE
-8.68

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-2.80
Current EV/EBITDA
-25.41
Overvalued EV/EBITDA
1.13
Undervalued EV/EBITDA
-6.73

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
16.45
Current PS
27.04
Overvalued PS
28.85
Undervalued PS
4.06

Financials

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Whales Holding WVE

B
Bluebox Asset Management Uk Ltd.
Holding
WVE
+20.01%
3M Return
D
Driehaus Capital Management LLC
Holding
WVE
+14.61%
3M Return
A
Artal Group S.A.
Holding
WVE
+14.33%
3M Return
T
Tang Capital Management, LLC
Holding
WVE
+3.72%
3M Return
R
RA Capital Management, L.P.
Holding
WVE
+3.71%
3M Return
S
Sofinnova Investment, Inc.
Holding
WVE
+1.88%
3M Return

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Frequently Asked Questions

What is WAVE Life Sciences Ltd (WVE) stock price today?

The current price of WVE is 7.18 USD — it has decreased -0.83

What is WAVE Life Sciences Ltd (WVE)'s business?

Wave Life Sciences Ltd. is a biotechnology company focused on unlocking the broad potential of ribonucleic acid (RNA) medicines to transform human health. The Company’s RNA medicines platform, PRISM, combines multiple modalities, chemistry innovation and deep insights in human genetics to deliver scientific breakthroughs that treat both rare and common disorders. Its toolkit of RNA-targeting modalities includes editing, splicing, RNA interference and antisense silencing, providing Wave with unmatched capabilities for designing and sustainably delivering candidates that optimally address disease biology. The Company’s diversified pipeline includes clinical programs in alpha-1 antitrypsin deficiency, obesity, Duchenne muscular dystrophy, and Huntington’s disease, as well as several preclinical programs utilizing the Company’s broad RNA therapeutics toolkit. Its programs include WVE-006, SERPINA1 (AATD); WVE-007 (GalNAc), INHBE (Obesity); WVE-N531, Exon 53 (DMD), and WVE-003, mHTT (HD).

What is the price predicton of WVE Stock?

Wall Street analysts forecast WVE stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for WVE is33.00 USD with a low forecast of 21.00 USD and a high forecast of 50.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is WAVE Life Sciences Ltd (WVE)'s revenue for the last quarter?

WAVE Life Sciences Ltd revenue for the last quarter amounts to 38.25M USD, increased 316.85

What is WAVE Life Sciences Ltd (WVE)'s earnings per share (EPS) for the last quarter?

WAVE Life Sciences Ltd. EPS for the last quarter amounts to -0.13 USD, decreased -55.17

How many employees does WAVE Life Sciences Ltd (WVE). have?

WAVE Life Sciences Ltd (WVE) has 317 emplpoyees as of May 10 2026.

What is WAVE Life Sciences Ltd (WVE) market cap?

Today WVE has the market capitalization of 1.38B USD.