SYRE Technical Analysis & Stock Price Forecast

Technical Sentiment

Overall Consensus

Sell

Buy

Technical Analysis Consensus

Sell

Buy

Moving Average Consensus

Sell

Buy

Spyre Therapeutics Inc (SYRE) Moving Averages Convergence Divergence (MACD) indicator is 2.95, suggesting SYRE is Strong Buy.

Spyre Therapeutics Inc (SYRE) 20-Day simple moving average is 72.173, while Spyre Therapeutics Inc (SYRE) share price is $72.02, making it Sell.

Spyre Therapeutics Inc (SYRE) 60-Day simple moving average is 57.109, while Spyre Therapeutics Inc (SYRE) share price is $72.02, making it Buy.

Technical Analysis for SYRE

Technical Sentiment Analysis for Spyre Therapeutics Inc (SYRE) As of 2026-05-20, Spyre Therapeutics Inc (SYRE) is exhibiting a Strong Buy technical sentiment. Our proprietary analysis, which aggregates 12 technical signals, shows that 8 indicators are flashing buy, while 4 are indicating sell.

Momentum Indicators: RSI, MACD & Overbought/Oversold Status Currently, the Relative Strength Index (RSI) for SYRE stands at 55.111, which suggests a Neutral condition. Meanwhile, the MACD (12, 26) indicator is at 2.95, providing a Buy signal for short-term momentum. Other oscillators like the Stochastic Oscillator at 30.022 and the Commodity Channel Index (CCI) at -50.038 further confirm a -1.08 outlook for the stock.

Support, Resistance & Moving Averages From a structural perspective, SYRE is trading above its 60-day moving average of $57.109 and above its 200-day long-term moving average of $34.87. Key price levels to watch include the immediate resistance at $79.984 and strong support at $65.854. A break above $79.984 could signal a bull continuation, while falling below $65.854 may test the next Fibonacci floor at $58.197.

Spyre Therapeutics Inc (SYRE) Support & Resistance Level

Name	S3	S2	S1	Pivot Points	R1	R2	R3
Classic	51.724	58.197	65.854	72.327	79.984	86.457	94.114
Fibonacci	58.197	63.595	66.93	72.327	77.725	81.06	86.457

Spyre Therapeutics Inc (SYRE) Technical Indicators

2026-05-20

Name	Value
RSI_14	55.111
STOCHk_14_3_3	30.022
STOCHd_14_3_3	39.988
CCI_20	-50.038
AO_5_34	4.273
MOM_10	-1.08
MACD_12_26_9	2.95

Spyre Therapeutics Inc (SYRE) Relative Strength Index (RSI) is 55.111, creating a Neutral signal.

Spyre Therapeutics Inc (SYRE) Stochastic Oscillator is 30.022, creating a Neutral signal.

Spyre Therapeutics Inc (SYRE) Stochastic RSI is 39.988, creating a Neutral signal.

Spyre Therapeutics Inc (SYRE) Commodity Channel Index (CCI) is -50.038, creating a Neutral signal.

Spyre Therapeutics Inc (SYRE) Awesome Oscillator is 4.273, creating a Buy signal.

Spyre Therapeutics Inc (SYRE) Momentum is -1.08, creating a Sell signal.

Spyre Therapeutics Inc (SYRE) MACD is 2.95, creating a Buy signal.

Spyre Therapeutics Inc (SYRE) Moving Average

2026-05-20

Period	Simple	Signal
MA_5	71.838	Buy
MA_10	73.511	Sell
MA_20	72.173	Sell
MA_60	57.109	Buy
MA_200	34.87	Buy
MA_250	31.135	Buy

Spyre Therapeutics Inc (SYRE) 5-Day simple moving average is 71.838, while Spyre Therapeutics Inc (SYRE) share price is $72.02, making it a Buy.

Spyre Therapeutics Inc (SYRE) 10-Day simple moving average is 73.511, while Spyre Therapeutics Inc (SYRE) share price is $72.02, making it a Sell.

Spyre Therapeutics Inc (SYRE) 20-Day simple moving average is 72.173, while Spyre Therapeutics Inc (SYRE) share price is $72.02, making it a Sell.

Spyre Therapeutics Inc (SYRE) 60-Day simple moving average is 57.109, while Spyre Therapeutics Inc (SYRE) share price is $72.02, making it a Buy.

Spyre Therapeutics Inc (SYRE) 200-Day simple moving average is 34.87, while Spyre Therapeutics Inc (SYRE) share price is $72.02, making it a Buy.

Spyre Therapeutics Inc (SYRE) 250-Day simple moving average is 31.135, while Spyre Therapeutics Inc (SYRE) share price is $72.02, making it a Buy.

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Frequently Asked Questions

What is the current technical consensus for SYRE?

The overall technical consensus for Spyre Therapeutics Inc (SYRE) is currently Strong Buy. This rating is derived from a combined analysis of moving averages and oscillators, currently showing 4 buy signals and 2 sell signals.

What are the key support and resistance levels for Spyre Therapeutics Inc (SYRE) today?

Based on pivot point calculations, Spyre Therapeutics Inc (SYRE) has an immediate support level at 65.854 and a major resistance level at 79.984. Traders also monitor the pivot point at 72.327 to determine the intraday trend direction.

Is Spyre Therapeutics Inc (SYRE) overbought or oversold based on the RSI?

The Relative Strength Index (RSI) for Spyre Therapeutics Inc (SYRE) is currently 55.111. This indicates that the stock is in neutral territory (typically, a value below 30 is oversold and above 70 is overbought).

What signal is the MACD providing for Spyre Therapeutics Inc (SYRE)?

Spyre Therapeutics Inc (SYRE) Moving Averages Convergence Divergence (MACD) indicator is 2.95, suggesting SYRE is Strong Buy. This indicator helps identify potential trend reversals or momentum shifts for Spyre Therapeutics Inc.

How is Spyre Therapeutics Inc (SYRE) performing relative to its 200-day moving average?

Spyre Therapeutics Inc (SYRE) is currently trading at $72.02, which is above its 200-day simple moving average of 34.87. Trading above the 200-day MA is often used by investors to determine the long-term bullish or bearish trend.