SYRE Forecast — Price Prediction for 2025. Should I Buy SYRE?

1-Day-Price-Prediction

-0.57%

1-Week Prediction

+1.91%

1-Month Prediction

+7.77%

2026 Prediction

-100%

2030 Prediction

-100%

Based on our advanced algorithm, we have generated comprehensiveSYRE stock price predictions for multiple time horizons. Our models indicate potential volatility in the short term, with specific targets calculated for the 1-day and 1-week outlooks.

Looking further ahead, our analysts have pinpointed significant trend shifts in the longer-term data. We have exclusive projections available for the 1-month forecast, a detailed 2026 projection, and a long-range 2030 forecast that reveals potential upside or downside risks.

Unlock the full analysis to access these precise price targets and see exactly where our models predict SYRE is heading. Stay informed and make strategic decisions with our premium data-driven insights!

Should I Buy Spyre Therapeutics Inc Stock?

Based on our evaluation of the five key dimensions—Technical Signals, Moving Average trends, Short Sell Data, Similar Chart Pattern Matching and Seasonality Analysis—we have identified the following insights. SYRE has several positive signals and is within a rising trend, so we believe it will perform strongly in the next couple of days or weeks. We therefore hold a positive evaluation of this stock. Our analysis conclusion for this stock is a Strong Buy candidate.

SYRE stock price ended at $30.53 on Friday, after rising 1.29%

The Spyre Therapeutics Inc stock price increased by 1.29% on the last trading day (09 Jan 2026), rising from 30.42 to 30.14. Throughout the last trading session, the stock experienced a fluctuation of 3.73% , ranging from a day low of $29.6 to a day high of 30.705. The price has declined in 7 of the last 10 days, resulting in a total change of -9.30% during this period. On the last day, trading volume increase by -19.37K shares, with the rising prices. This could serve as an early warning, indicating that risk may slightly increase in the coming days. In total, 569.34K shares were traded, amounting to approximately 17.11M.

SYRE Technical Signals

SYRE(Spyre Therapeutics Inc Corp) has 3 buy signals and 3 sell signals now. The current trend is an uptrend starting from 2026-01-05. The total price change during this trend is +0.60%. Recently, the price has dropped while volume increased, indicating a strong bearish signal. The average turnover of SYRE over the last 5 trading days is 23.00M. Overall, the technical indicator signals lean more toward a Neutral outlook in the mid-term.

SYRE Moving Average Analysis

Spyre Therapeutics Inc's overall moving average trend leans more bullish as of Friday, January 9, 2026, with 1 negative signals and 3 positive signal. In the mid-term, the SMA_20 being above the SMA_60 signals a strong bullish trend. There will be some resistance from the lines at $34.98, and $37.31. A break-up above any of these levels will issue buy signals. There will be some support from the lines at $27.44, and $25.11. A break-down below any of these levels will issue sell signals.

SYRE Short Selling Analysis

The short sale ratio of Spyre Therapeutics Inc(SYRE) as of 10 Dec 2025 is 23.83%, rising from last trading day. With increasing price from 33.68 to 34.66. The short sell activity indicate that short sellers may be anticipating a price reversion.

Technical Signal

Technical Signals Summary

Sell

Buy

Moving Average

Swing

Positive

Stock Price Above SMA_5

Short Term

Negative

SMA_5 Below SMA_20

Mid Term

Positive

SMA_20 Above SMA_60

Long Term

Positive

SMA_60 Above SMA_200

Short Selling

Close Price

Short Sale Ratio

Short Sale Volume

3 Bullish Signals

When Value satisfies Signal, Indicator signals Bullish

Indicators

Signal

Value

Meaning

Commodity Channel Index (20 days, 0.015 constant)

CCI_20_0.015 < -100

-136.77

Bullish

Moving Average Convergence Divergence (12, 26, 9)

MACD_12_26_9 > 0

0.33

Bullish

Stochastic RSI %K (14, 14, 3, 3)

STOCHRSIk_14_14_3_3 < 20

12.16

Bullish

3 Bearish Signals

When Value satisfies Signal, Indicator signals Bearish

Indicators

Signal

Value

Meaning

Awesome Oscillator (5, 34)

AO_5_34 < 0

-0.868

Bearish

Momentum (10 days)

MOM_10 < 0

-3.09

Bearish

Moving Average

Price crosses below 5-day SMA

Bearish

SYRE Stock Forecast

2026

2027

2028

2029

2030

2031

2032

2033

2034

2035

Month	Min. Price	Avg. Price	Max. Price	Potential ROI

In 2026, Spyre Therapeutics Inc (SYRE) is anticipated to change hands in a trading channel between $0.00 and $0.00.

Spyre Therapeutics Inc Stock Forecast 2026

SYRE Price Prediction & Forecast by Similar Chart Analysis

Based on historical patterns and backtesting of stocks with similar movements to Spyre Therapeutics Inc(SYRE), our algorithm predicts SYRE's 1-month price at $31.85, with an 4.15%upwardshift. Using a similarity score up to 97.53%and other factors, This forecast updates weekly, adjusting for significant deviations.

Similar Chart

The price prediction chart for Spyre Therapeutics Inc (SYRE.O) stock, as of Sunday, January 4, 2026 , forecasts a 4.15% change over the next month, based on its high correlation with CLBT.O stock patterns. The similarity between their price movements over the analyzed periods is 97.53%. The right panel lists other stocks with similar price patterns. This prediction is updated every week.

SYRE

No data

CLBT

Up: 4.15%Similarity: 97.53%

Name

Similarity

Up/Down

CLBT.O

97.53%

+4.15%

GRCE.O

97.27%

+5.10%

AAOI.O

97.15%

-5.65%

AKAM.O

96.97%

-1.19%

SIM.A

96.96%

+4.93%

ETD.N

96.95%

+1.60%

GABC.O

96.95%

+7.57%

MHO.N

96.90%

-7.61%

VSAT.O

96.72%

+3.17%

E.N

96.68%

+2.29%

SYRE Seasonality Analysis

Based on SYRE's historical stock price data across all years, the probability of a positive return in January is40.00%, suggesting it maynotbe an ideal month to invest in SYRE. In contrast,Augustoffers the highest probability of positive returns at80.00%, making it a potentially strong month for investment.

However, this is only a prediction based on one method, and a comprehensive assessment of the stock's future trend should consider additional factors. Our final stock price commentary incorporates three main evaluation dimensions: technical signals, Moving Average trends, and similar chart pattern matching, with the first two dimensions carrying the primary weight to ensure a more robust and accurate forecast.

Monthly Seasonality

The radar chart shows that buying Spyre Therapeutics Inc (SYRE.O) stock in August has the highest probability of a positive return (80.00%), while April has the lowest probability (22.22%).

Performance Seasonality

The chart shows Spyre Therapeutics Inc. (SYRE)'s annual stock price return for the past three years, helping you analyze price trends and identify recurring trends on an annual basis.

People Also Watch

Frequently Asked Questions

Should I buy Spyre Therapeutics Inc (SYRE.O) stock?

Which months have the highest win rate for buying Spyre Therapeutics Inc (SYRE.O) stock in a year?

The radar chart shows that buying Spyre Therapeutics Inc (SYRE.O) stock in August has the highest probability of a positive return (80.00%), while April has the lowest probability (22.22%).

How has Spyre Therapeutics Inc. (SYRE)'s stock price performed over the past three years?

SYRE's stock price rose by 8.79% in 2024,increased by 37.36% in 2025, and went down by 0.16%in 2026.

Which bullish technical signals does SYRE have?

Bullish technical signals of SYRE include: CCI_20_0.015 < -100, MACD_12_26_9 > 0, STOCHRSIk_14_14_3_3 < 20.

Which bearish technical signals does SYRE have?

Bearish technical signals of SYRE include: AO_5_34 < 0, MOM_10 < 0, Price crosses below 5-day SMA.

Is SYRE a buy based on overall technical signals summary?

SYRE has 3 buy signals and 3 sell signals now. Overall the technical rating for SYRE is Neutral . Note that market conditions change all the time. In addition to technical ratings, keep an eye on the Valuation Level of SYRE.

What is the trend of Spyre Therapeutics Inc (SYRE)'s moving average?

Spyre Therapeutics Inc's overall moving average trend leans more bullish as of January 09 2026, with 1 negative signals and 3 positive signal.

What is price prediction for SYRE stock next month?

The price prediction chart for Spyre Therapeutics Inc (SYRE.O) stock, as of January 04 2026, forecasts a 4.15% change over the next month, based on its high correlation with CLBT stock patterns. The similarity between their price movements over the analyzed periods is 97.53%. The right panel lists other stocks with similar price patterns. This prediction is updated every week.

What is price prediction 2026 for Spyre Therapeutics Inc (SYRE) Stock?

In , Spyre Therapeutics Inc's value is forecasted to reach an average price of $NaN. The price is predicted to fluctuate between a low of $NaN and a high of $NaN.

What is price prediction 2030 for Spyre Therapeutics Inc (SYRE) Stock?

In , Spyre Therapeutics Inc's value is forecasted to reach an average price of $NaN. The price is predicted to fluctuate between a low of $NaN and a high of $NaN.

SYRE Stock Price Prediction

SYRE Stock Price Prediction

Should I Buy Spyre Therapeutics Inc Stock?

SYRE stock price ended at $30.53 on Friday, after rising 1.29%

SYRE Technical Signals

SYRE Moving Average Analysis

SYRE Short Selling Analysis

Technical Signal

Technical Signals Summary

Moving Average

Short Selling

SYRE Stock Forecast

SYRE Price Prediction & Forecast by Similar Chart Analysis

No data

SYRE Seasonality Analysis

Monthly Seasonality

Performance Seasonality

People Also Watch

Frequently Asked Questions

Should I buy Spyre Therapeutics Inc (SYRE.O) stock?

Which months have the highest win rate for buying Spyre Therapeutics Inc (SYRE.O) stock in a year?

How has Spyre Therapeutics Inc. (SYRE)'s stock price performed over the past three years?

Which bullish technical signals does SYRE have?

Which bearish technical signals does SYRE have?

Is SYRE a buy based on overall technical signals summary?

What is the trend of Spyre Therapeutics Inc (SYRE)'s moving average?

What is price prediction for SYRE stock next month?

What is price prediction 2026 for Spyre Therapeutics Inc (SYRE) Stock?

What is price prediction 2030 for Spyre Therapeutics Inc (SYRE) Stock?