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Based on our advanced algorithm, we have generated comprehensive SYRE stock price predictions for multiple time horizons. Our models indicate potential volatility in the short term, with specific targets calculated for the 1-day and 1-week outlooks.
Looking further ahead, our analysts have pinpointed significant trend shifts in the longer-term data. We have exclusive projections available for the 1-month forecast, a detailed 2026 projection, and a long-range 2030 forecast that reveals potential upside or downside risks.
Unlock the full analysis to access these precise price targets and see exactly where our models predict SYRE is heading. Stay informed and make strategic decisions with our premium data-driven insights!

Swing
Stock Price Above SMA_5
Short Term
SMA_5 Below SMA_20
Mid Term
SMA_20 Above SMA_60
Long Term
SMA_60 Above SMA_200
The radar chart shows that buying Spyre Therapeutics Inc (SYRE.O) stock in August has the highest probability of a positive return (80.00%), while April has the lowest probability (22.22%).
SYRE's stock price rose by 8.79% in 2024,increased by 37.36% in 2025, and went up by 7.72%in 2026.
Bullish technical signals of SYRE include: AO_5_34 > 0, MACD_12_26_9 > 0, Price crosses above 5-day SMA, Price crosses above 10-day SMA, Price crosses above 20-day SMA.
Bearish technical signals of SYRE include: MOM_10 < 0, 5-day SMA crosses below 20-day SMA.
SYRE has 5 buy signals and 2 sell signals now. Overall the technical rating for SYRE is Buy . Note that market conditions change all the time. In addition to technical ratings, keep an eye on the Valuation Level of SYRE.
Spyre Therapeutics Inc's overall moving average trend leans more bullish as of February 06 2026, with 1 negative signals and 3 positive signal.
The price prediction chart for Spyre Therapeutics Inc (SYRE.O) stock, as of February 01 2026, forecasts a 57.5% change over the next month, based on its high correlation with GRCE stock patterns. The similarity between their price movements over the analyzed periods is 91.66%. The right panel lists other stocks with similar price patterns. This prediction is updated every week.
In , Spyre Therapeutics Inc's value is forecasted to reach an average price of $NaN. The price is predicted to fluctuate between a low of $NaN and a high of $NaN.
In , Spyre Therapeutics Inc's value is forecasted to reach an average price of $NaN. The price is predicted to fluctuate between a low of $NaN and a high of $NaN.