PGEN.O News & Events

The major averages bounced back in the late afternoon, finishing mostly unchanged amid uncertainty over an imminent end to the U.S.-Iran war. President Trump has established an 8:00 pm ET deadline for the two sides to reach an agreement to reopen the Strait of Hormuz, otherwise the U.S. will attack Iran's power plants and bridges. Trump's recent comments include the president saying on Truth Social, "A whole civilization will die tonight, never to be brought back again. I don't want that to happen, but it probably will." Axios later reported that U.S.-Iran talks are showing some signs of progress, while adding that a ceasefire deal by the Tuesday deadline remains unlikely.The major indexes pared much of their losses late in the session after Pakistan's prime minister requested that President Trump extend the deadline by two weeks, and requested Iran open the Strait of Hormuz as a gesture of goodwill.Get caught up quickly on the top news and calls moving stocks with these five Top Five lists.1. STOCK NEWS:The Centers for Medicare and Medicaid released its, with policies project to result in a net average increase of 2.48%.Broadcomand Alphabetentered into aPershing Squareall outstanding shares of Universal Music GroupNikkei Asia said that Apple'sfoldable iPhone has, but Bloomberg countered that the device remains on track for a September debutAnthropic announced, an initiative to "secure the world's most critical software, in partnership with Amazon Web Services, Anthropic, Apple, Broadcom, Cisco, CrowdStrike, Google, JPMorganChase, the Linux Foundation, Microsoft, Nvidia, and Palo Alto Networks2. WALL STREET CALLS:Armto Equal Weight at Morgan StanleyRosenblattArista Networkson increased confidence in XPO strategyBarringtonFuboTVto Outperform on updated financial outlookCitiWingstopto Buy into potential sales reboundRocket Labto Outperform at Citizens3. AROUND THE WEB:Pimco is mulling a $14B debt financing deal to construct a massive Oracledata center in Michigan, Bloomberg reportsKimberly-Clarktold Bloomberg it is aware of a firer at its California distribution centerAmazonhas rebuffed requests from its wholesale suppliers for increased payments to cover higher costs, prompting some to pull items from the company's site, Information reportsThe families behind Puigand Estee Lauderare set to meet in New York this week to negotiate the terms of a potential combination of their beauty businesses with the goal of announcing an agreement in the coming weeks, Expansion saysDelta Air Lineshas hiked its fee for checked bags by $10 for tickets bought starting Wednesday, following similar moves by Unitedand JetBlueamid a surge in jet fuel expenses this year, CNBC says4. MOVERS:Patterson-UTIgains after reportingoperating in the U.S. in MarchPerrigoincreases in New York after a rumor was highlighted inMach Naturaldeclines after announcing aRedwirelower afterwith a new office in the United KingdomSuzanofalls in New York after BofAthe stock to Neutral5. EARNINGS/GUIDANCE:PrecigenprovidedSamsungreportedNeuroneticsbacked itsand FY26RPM Internationalis expected toon April 8Levi Straussis expected toon April 7INDEXES:The Dow fell 85.42, or 0.18%, to 46,584.46, the Nasdaq gained 21.51, or 0.098%, to 22,017.85, and the S&P 500 advanced 5.02, or 0.076%, to 6,616.85.

The major averages were lower near noon, erasing yesterday's gains amid fading hopes of an imminent end to the U.S.-Iran war and oil prices surpassing $117 per barrel. President Trump has established an 8:00 pm ET deadline for the two sides to reach an agreement to reopen the Strait of Hormuz, otherwise the U.S. will attack Iran's power plants and bridges. Trump's recent comments include the president saying on Truth Social, "A whole civilization will die tonight, never to be brought back again. I don't want that to happen, but it probably will."Get caught up quickly on the top news and calls moving stocks with these five Top Five lists.1. STOCK NEWS:The Centers for Medicare and Medicaid released its 2027 Medicare Advantage payments, with policies project to result in aBroadcomand Alphabetentered into aPershing Square proposed toof Universal Music GroupApple'sfoldable iPhone has encountered setbacks,Organogenesissaid itin its PuraPly study2. WALL STREET CALLS:Armto Equal Weight at Morgan StanleyRosenblattArista Networkson increased confidence in XPO strategyBarringtonFuboTVto Outperform on updated financial outlookCitiWingstopto Buy into potential sales reboundRocket Labto Outperform at Citizens3. AROUND THE WEB:Amazonhas rebuffed requests from its wholesale suppliers for increased payments to cover higher costs, prompting some to pull items from the company's site, Information reportsThe families behind Puig and Estee Lauderare set to meet in New York this week to negotiate the terms of a potential combination of their beauty businesses with the goal of announcing an agreement in the coming weeks, Expansion saysUlta BeautyCEO Kecia Steelman said GLP-1 users are purchasing hair and skincare products to combat the side effects of the weight loss treatments, Business Insiders reportsDelta Air Lineshas hiked its fee for checked bags by $10 for tickets bought starting Wednesday, following similar moves by Unitedand JetBlueamid a surge in jet fuel expenses this year, CNBC saysAnthropic plans to invest $200M in a new venture with private equity firms that looks to sell AI tools to their portfolio companies amid a push for business customers, WSJ reports4. MOVERS:Patterson-UTIgains after reportingn the U.S. in MarchPerrigoincreases in New York after ain Ben Harrington's Betaville blogMach Naturaldeclines after announcing aRedwirelower afterwith a new office in the United KingdomSuzanofalls in New York after BofAthe stock to Neutral5. EARNINGS/GUIDANCE:PrecigenSamsungNeuroneticsfor Q1 and FY26RPM Internationalis expectedon April 8Levi Straussis expectedon April 7INDEXES:Near midday, the Dow was down 0.81%, or 377.95, to 46,291.93, the Nasdaq was down 1.10%, or 241.75, to 21,754.59, and the S&P 500 was down 0.81%, or 53.79, to 6,558.04.

Stock futures are modestly lower this morning. Markets are pausing after a four-day rebound, with sentiment turning cautious again as investors head into a key geopolitical deadline. The central driver remains the standoff in the Middle East, specifically the U.S. deadline for Iran to reopen the Strait of Hormuz. With Tehran rejecting both the deadline and ceasefire proposals, markets are now bracing for a potential escalation scenario rather than a negotiated outcome. That shift in expectations is pushing oil back higher and reintroducing the same inflation concerns that drove volatility throughout March.The oil move is once again dictating cross-asset behavior. Higher crude is tightening financial conditions, pressuring equities, and complicating the Federal Reserve outlook.Energy-linked assets are benefiting from the renewed supply shock narrative, while oil-sensitive sectors, particularly airlines and transports, are coming back under pressure. At the same time, defensive pockets of the market are seeing inflows, and health insurers are outperforming following favorable policy updates. Volatility is elevated and that dynamic is keeping risk appetite contained despite the recent bounce.In pre-market trading, S&P 500 futures fell 0.38%, Nasdaq futures fell 0.55% and Dow futures fell 0.30%.Check out this morning's top movers from around Wall Street, compiled by The Fly.HIGHER -Organogenesisup 17% after reporting it has met the primary endpoint in its PuraPly studyHumana, UnitedHealthand CVS Healthup 10%, 8% and 7% respectively after Centers for Medicare & Medicaid Services finalized Medicare payment policy at higher-than-expected ratesBroadcomup 3% after entering into a long-term agreement for the company to develop and supply custom TPUs for Google'sfuture generations of TPUs and a supply assurance agreement for Broadcom to supply networking and other components to be used in Google's next-generation AI racks through up to 2031Casey's General Storesup 1% after being admitted into the S&P 500 indexLOWER -ATN Internationaldown 1% after announcing Brad Martin is stepping down as CEO and member of the company's board of directorsEstee Lauderdown 1% after Spanish newspaper Expansion reported the families behind Puig and Estee Lauder are set to meet in New York this week to negotiate the terms of a potential combination of their beauty businesses with the goal of announcing an agreement in the coming weeksPrecigendown 1% after providing Q1 revenue guidance

"In the short time since early and full approval, the standard-of-care first-line treatment is seeing tremendous progress," said Precigen's President and CEO, Helen Sabzevari, during a conference call to discuss fourth quarter results. "This substantial advancement constitutes a pivotal milestone for all stakeholders impacted by RRP." As a result of the interest in PAPZIMEOS, Sabzevari said the company is transforming from a research and development biopharmaceutical company to a product revenue generating biotech company. Net product sales of PAPZIMEOS were $3.4M in the fourth quarter of 2025, with shipments commencing in November. In the fourth quarter, Precigen patient hub enrollment surpassed 300, a testament to physician and patient demand. Sabzevari noted the company expects revenue in the first quarter of 2026 to exceed $18M given the momentum of PAPZIMEOS. "This is a clear sign of the enthusiasm we are seeing from patients and physicians alike, leading to a robust use of the immunotherapy," she said.