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PCVX Overview

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0.000(0.000%)Aft-market
ET
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0.000
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0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
56.220
Open
55.500
VWAP
55.13
Vol
1.00M
Mkt Cap
7.87B
Low
54.490
Amount
55.34M
EV/EBITDA(TTM)
--
Total Shares
143.92M
EV
6.49B
EV/OCF(TTM)
--
P/S(TTM)
--
Vaxcyte Inc. is a clinical-stage vaccine innovation company. The Company is engaged in developing spectrum conjugate and protein vaccines to prevent or treat bacterial infectious diseases. Its pipeline includes VAX-31, a 31-valent PCV candidate advancing to a Phase III adult clinical program and being evaluated in a Phase II infant clinical program, which is being developed for the prevention of invasive pneumococcal disease (IPD) in adults and infants and is the broadest-spectrum pneumococcal conjugate vaccine (PCV) candidate in the clinic. VAX-24, the Company’s 24-valent PCV candidate, is designed to cover more serotypes than any infant PCV on-market and is being evaluated in a Phase II infant study. Its pipeline also includes VAX-A1, a prophylactic vaccine candidate designed to prevent Group A Strep infections; VAX-PG, a therapeutic vaccine candidate designed to slow or stop the progression of periodontal disease; and VAX-GI, a vaccine candidate designed to prevent Shigella.
Show More

Events Timeline

(ET)
2026-03-23
09:10:00
Vaxcyte Completes Enrollment in VAX-31 OPUS-1 Trial
select
2026-03-18 (ET)
2026-03-18
19:50:00
Vaxcyte Publishes Positive Results of VAX-31 Clinical Study
select
2026-02-24 (ET)
2026-02-24
16:20:00
Vaxcyte Advances VAX-31 Clinical Trials
select
2026-02-11 (ET)
2026-02-11
16:30:00
Vaxcyte Begins OPUS-3 Trial Evaluating VAX-31 Vaccine
select
2026-01-30 (ET)
2026-01-30
06:10:00
BofA and Others Increase Stock Offering Size to $550M
select
2026-01-29 (ET)
2026-01-29
19:50:00
BofA and Others Act as Joint Book-Running Managers for Offering
select

News

Newsfilter
5.0
11:42 AMNewsfilter
Vera Therapeutics Appoints New Chief Legal Officer
  • Executive Appointment: Vera Therapeutics has appointed Jane Wright-Mitchell as Chief Legal Officer, effective immediately, bringing extensive experience in regulatory approvals, commercialization, and intellectual property management, which will support the company as it approaches the launch of its first-in-class dual BAFF/APRIL inhibitor.
  • Enhanced Legal Support: With over 25 years of legal experience in the life sciences sector, including her role as General Counsel at Vaxcyte, Wright-Mitchell's expertise is expected to strengthen Vera's legal capabilities through key milestones and the potential commercial launch of atacicept.
  • Product Development Outlook: Vera's lead product candidate, atacicept, aims to treat IgA nephropathy as a subcutaneous injection administered weekly, which is anticipated to change the standard of care for patients and further enhance the company's market position in immunological diseases.
  • Strategic Collaboration and Innovation: Vera Therapeutics has secured an exclusive licensing agreement with Stanford University for the development of a next-generation fusion protein targeting BAFF and APRIL, known as VT-109, showcasing the company's broad potential in treating B-cell-mediated diseases.
Yahoo Finance
6.5
03-21Yahoo Finance
Kynam Capital Reduces Stake in Cogent Biosciences by $48 Million
  • Share Reduction Details: Kynam Capital disclosed in an SEC filing on February 17, 2026, that it sold 1,720,949 shares of Cogent Biosciences in Q4, with an estimated transaction value of $48.38 million, indicating a cautious approach towards the company's future prospects.
  • Ownership Proportion Change: Following this sale, Cogent Biosciences now represents 13.99% of Kynam's reported AUM, yet it remains the fund's largest holding, reflecting ongoing confidence in its core investment despite the reduction.
  • Market Performance Analysis: Cogent's stock price surged 360% over the past year, significantly outperforming the S&P 500's 15% gain during the same period, highlighting its strong performance and market recognition in the biotech sector.
  • Future Outlook: Cogent's lead product, bezuclastinib, received FDA acceptance, with a target decision date set for December 30, 2026, and with $900.8 million in cash reserves, the company is well-positioned to support future R&D and market expansion efforts.
Benzinga
6.0
02-26Benzinga
Wall Street Analysts Adjust Ratings
  • Analyst Rating Changes: Top Wall Street analysts have adjusted their ratings on several stocks, reflecting varying market outlooks that could influence investor decisions and market trends.
  • Upgrades and Downgrades: While specific stock names are not mentioned, such rating changes typically lead to stock price volatility, prompting investors to pay close attention to these shifts for portfolio optimization.
  • Market Reaction Expectations: The adjustments in analysts' ratings may trigger short-term market reactions, especially when investor sentiment towards specific stocks is sensitive, thereby impacting overall market sentiment.
  • Enhanced Information Transparency: By providing a comprehensive view of analyst rating changes, investors can better understand market dynamics and make more informed investment decisions, thereby improving market transparency and efficiency.
NASDAQ.COM
9.5
02-25NASDAQ.COM
Vaxcyte Reports Q4 and Full-Year 2025 Financial Results and Business Update
  • Widening Financial Losses: Vaxcyte reported a net loss of $246.5 million for Q4 2025, significantly up from $137.1 million in the same quarter last year, with a full-year net loss of $766.6 million compared to $463.9 million previously, indicating ongoing investments in R&D and operations.
  • VAX-31 Clinical Progress: The company's lead 31-valent pneumococcal conjugate vaccine, VAX-31, is undergoing three pivotal Phase 3 trials, with topline data from OPUS-1 expected in Q4 2026, which will provide critical insights for its adult market launch, supported by FDA's Breakthrough Therapy Designation.
  • Manufacturing Facility Development: In Q4 2025, Vaxcyte incurred an additional $21.8 million in expenditures for the construction of its dedicated Lonza manufacturing facility, bringing total expenditures to $335.4 million by year-end, with completion in Q1 2026, aimed at supporting the global commercialization of its PCV program.
  • New Vaccine Candidates: Beyond VAX-31, Vaxcyte is advancing multiple vaccine candidates including VAX-24, VAX-XL, VAX-A1, and VAX-GI, showcasing the company's diversified strategy in vaccine development, particularly innovative solutions targeting various pathogens.
seekingalpha
9.5
02-24seekingalpha
Vaxcyte Reports Q4 Losses and Cash Position
  • Earnings Miss: Vaxcyte reported a Q4 GAAP EPS of -$5.63, missing estimates by $4.06, indicating significant challenges in profitability that could undermine investor confidence.
  • Cash Position: As of December 31, 2025, Vaxcyte holds approximately $2.4 billion in cash, cash equivalents, and investments, highlighting a strong liquidity position, yet future operational expenditures remain a concern.
  • Funding Initiative: The company is proposing a $500 million public offering of stock and warrants to bolster its capital structure for future R&D and operations, although market reactions may be tempered by the recent earnings miss.
  • Market Impact: Following FDA officials' comments on future vaccine approvals, shares of Moderna and other vaccine makers declined, reflecting market concerns about the vaccine sector's outlook, which could have a ripple effect on Vaxcyte's stock price.
NASDAQ.COM
9.0
02-12NASDAQ.COM
Vaxcyte Initiates Phase 3 Trial for VAX-31 Vaccine
  • Trial Launch: Vaxcyte announced the dosing of first participants in the OPUS-3 Phase 3 trial for VAX-31, a next-generation 31-valent pneumococcal conjugate vaccine aimed at enhancing immune responses against pneumococcus, which is expected to significantly improve vaccination outcomes in adults.
  • Trial Scale and Design: The study will enroll approximately 720 adults aged 50 and older across 30 U.S. sites, with participants randomized to receive either VAX-31 or PCV20, assessing safety, tolerability, and immunogenicity, particularly in boosting immune responses in previously vaccinated individuals.
  • Enhanced Vaccine Coverage: VAX-31 is designed to cover approximately 95% of invasive pneumococcal disease and 88% of pneumococcal pneumonia, potentially providing 14-34% broader invasive disease coverage and 19-31% broader pneumonia coverage compared to current vaccines, which may significantly reduce the incidence of related diseases.
  • Future Data Expectations: Vaxcyte's broader Phase 3 adult program for VAX-31 includes OPUS-1 and OPUS-2, with key data expected in Q4 2026 and H1 2027 respectively, further advancing the vaccine's market application and Biologics License Application (BLA).
Wall Street analysts forecast PCVX stock price to rise
6 Analyst Rating
Wall Street analysts forecast PCVX stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
50.00
Averages
104.80
High
163.00
Current: 0.000
sliders
Low
50.00
Averages
104.80
High
163.00
TD Cowen
Tara Bancroft
Buy
upgrade
$50 -> $75
AI Analysis
2026-02-25
Reason
TD Cowen
Tara Bancroft
Price Target
$50 -> $75
AI Analysis
2026-02-25
upgrade
Buy
Reason
TD Cowen analyst Tara Bancroft raised the firm's price target on Vaxcyte to $75 from $50 and keeps a Buy rating on the shares. The firm said Vaxcyte enters 2026 with a largely de-risked path for VAX-31, supported by differentiated Phase II data and a comprehensive Phase III OPUS program targeting BLA filing in 2027.
Goldman Sachs
Neutral
maintain
$38 -> $67
2026-02-25
Reason
Goldman Sachs
Price Target
$38 -> $67
2026-02-25
maintain
Neutral
Reason
Goldman Sachs raised the firm's price target on Vaxcyte to $67 from $38 and keeps a Neutral rating on the shares. Since coverage initiation, shares have risen steadily due to clinical progress on VAX-31, a slower-than-expected competitive landscape, and stable policy around the 4-dose infant schedule, contributing to year-to-date outperformance, the analyst tells investors in a research note. Upcoming VAX-31 Phase 3 adult data, Phase 2 pediatric readouts, and competitive developments viewed as key de-risking catalysts, the firm adds.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for PCVX
Unlock Now

Valuation Metrics

The current forward P/E ratio for Vaxcyte Inc (PCVX.O) is -7.31, compared to its 5-year average forward P/E of -11.84. For a more detailed relative valuation and DCF analysis to assess Vaxcyte Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-11.84
Current PE
-7.31
Overvalued PE
-7.53
Undervalued PE
-16.16

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-10.08
Current EV/EBITDA
-5.21
Overvalued EV/EBITDA
-5.04
Undervalued EV/EBITDA
-15.13

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
586.79
Current PS
162.18
Overvalued PS
1711.89
Undervalued PS
-538.31

Financials

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Whales Holding PCVX

P
Paradigm Biocapital Advisors LP
Holding
PCVX
+4.25%
3M Return
B
Boothbay Fund Management, LLC
Holding
PCVX
+2.52%
3M Return
W
Westfield Capital Management Company, L.P.
Holding
PCVX
+2.17%
3M Return
K
Kynam Capital Management, LP
Holding
PCVX
-0.24%
3M Return
E
EcoR1 Capital, LLC
Holding
PCVX
-0.51%
3M Return
P
Progeny 3, Inc.
Holding
PCVX
-4.72%
3M Return

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Frequently Asked Questions

What is Vaxcyte Inc (PCVX) stock price today?

The current price of PCVX is 54.67 USD — it has decreased -2.27

What is Vaxcyte Inc (PCVX)'s business?

Vaxcyte Inc. is a clinical-stage vaccine innovation company. The Company is engaged in developing spectrum conjugate and protein vaccines to prevent or treat bacterial infectious diseases. Its pipeline includes VAX-31, a 31-valent PCV candidate advancing to a Phase III adult clinical program and being evaluated in a Phase II infant clinical program, which is being developed for the prevention of invasive pneumococcal disease (IPD) in adults and infants and is the broadest-spectrum pneumococcal conjugate vaccine (PCV) candidate in the clinic. VAX-24, the Company’s 24-valent PCV candidate, is designed to cover more serotypes than any infant PCV on-market and is being evaluated in a Phase II infant study. Its pipeline also includes VAX-A1, a prophylactic vaccine candidate designed to prevent Group A Strep infections; VAX-PG, a therapeutic vaccine candidate designed to slow or stop the progression of periodontal disease; and VAX-GI, a vaccine candidate designed to prevent Shigella.

What is the price predicton of PCVX Stock?

Wall Street analysts forecast PCVX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PCVX is104.80 USD with a low forecast of 50.00 USD and a high forecast of 163.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Vaxcyte Inc (PCVX)'s revenue for the last quarter?

Vaxcyte Inc revenue for the last quarter amounts to -274.28M USD, increased 69.13

What is Vaxcyte Inc (PCVX)'s earnings per share (EPS) for the last quarter?

Vaxcyte Inc. EPS for the last quarter amounts to -233253000.00 USD, increased 64.93

How many employees does Vaxcyte Inc (PCVX). have?

Vaxcyte Inc (PCVX) has 507 emplpoyees as of March 25 2026.

What is Vaxcyte Inc (PCVX) market cap?

Today PCVX has the market capitalization of 7.87B USD.