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NUVB Overview

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0.000(0.000%)Aft-market
ET
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0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
4.470
Open
4.260
VWAP
4.38
Vol
2.29M
Mkt Cap
1.52B
Low
4.250
Amount
10.01M
EV/EBITDA(TTM)
--
Total Shares
347.60M
EV
1.20B
EV/OCF(TTM)
--
P/S(TTM)
23.78
Nuvation Bio Inc. is a global biopharmaceutical company. The Company is engaged in tackling the unmet needs in oncology by developing differentiated and therapeutic candidates. Its programs include taletrectinib (ROS1 inhibitor), safusidenib (mIDH1 inhibitor), NUV-1511 (drug-drug conjugate), and NUV-868 (BET inhibitor). The Company's Taletrectinib is an oral, potent, central nervous system-active, selective, ROS1 inhibitor specifically designed for the treatment of patients with ROS1-positive (ROS1+) non-small cell lung cancer (NSCLC). Safusidenib is a novel, oral, potent, brain penetrant, targeted inhibitor of mutant isocitrate dehydrogenase 1(mIDH1). NUV-1511, a clinical-stage drug-drug conjugate (DDC), fuses a targeting agent to a widely used chemotherapy agent. Its NUV-868 is a BD2-selective, oral, small molecule bromodomain and extra-terminal (BET) inhibitor that inhibits BRD4.
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Events Timeline

(ET)
2026-03-26
16:20:00
Nuvation Bio and Eisai Apply for Taletrectinib Marketing Authorization in EU
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2026-03-04 (ET)
2026-03-04
12:10:00
Nuvation Bio Shares Drop 25.3% to $4.36
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2026-03-04
10:10:00
Nuvation Bio Shares Drop 25.3% to $4.36
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2026-03-03 (ET)
2026-03-03
12:10:00
Nuvation Bio Shares Drop 25.6% to $4.34
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2026-03-03
10:10:00
Nuvation Bio Shares Drop 26.1% to $4.32
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2026-03-02 (ET)
2026-03-02
19:40:00
Middle East Turmoil Causes WTI Crude Oil to Surge Nearly 10%
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2026-03-02
16:10:00
Nuvation Bio Q4 Revenue $41.87M Beats Expectations
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2026-02-09 (ET)
2026-02-09
08:10:00
Nuvation Bio Finalizes Protocol Amendment for Phase 3 Trial of Safusidenib
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News

seekingalpha
9.0
03-26seekingalpha
Nuvation Bio and Eisai Apply for Lung Cancer Drug Approval
  • Application Accepted: The European Medicines Agency has accepted the Marketing Authorisation Application for taletrectinib filed by Nuvation Bio and Eisai, targeting non-small cell lung cancer, marking a significant advancement in the companies' oncology portfolio.
  • Review Timeline: The application is assigned a standard review period of 210 'active' days, which will influence the drug's time to market and potentially create new revenue streams for the companies.
  • Clinical Data Support: The application is backed by data from two pivotal Phase 2 studies, TRUST-I and TRUST-II, demonstrating taletrectinib's efficacy in treating non-small cell lung cancer, thereby enhancing market confidence in the drug.
  • Current Market Status: Taletrectinib is already marketed as Ibtrozi in the US and Japan, and obtaining approval in the European market will significantly bolster Nuvation Bio and Eisai's global expansion strategy.
moomoo
9.0
03-26moomoo
Eisai and Nuvation Bio Submit Marketing Authorization Application for Taletrectinib to Treat Advanced ROS1-Positive Non-Small Cell Lung Cancer, Approved by the European Medicines Agency
  • Announcement of New Treatment: A new application for the treatment of advanced ROS1-positive non-small cell lung cancer has been validated by the European Medicines Agency.

  • Significance of Validation: This validation marks a significant step forward in the marketing authorization process for a promising cancer therapy.

PRnewswire
7.0
03-26PRnewswire
Nuvation Bio Under Investigation, Stock Plummets 25.3%
  • Securities Fraud Investigation: Pomerantz LLP is investigating claims on behalf of Nuvation Bio Inc. investors regarding potential securities fraud or unlawful business practices by the company and its executives, which could further harm the company's reputation and stock price.
  • Earnings Report Impact: On March 2, 2026, Nuvation reported its Q4 and full-year 2025 financial results, revealing that approximately 75% of treatment discontinuations occurred among later-line patient populations, which may negatively affect near-term revenue trends and investor confidence.
  • Product Launch Challenges: During the commercial launch of IBTROZI (taletrectinib), Nuvation indicated that a significant share of early patient starts occurred in the third-line or later treatment settings, contributing to a gap between the number of patients starting treatment and net product revenue growth, potentially impacting future sales expectations.
  • Severe Stock Reaction: On March 3, 2026, Nuvation's stock price fell by $1.48, or 25.3%, closing at $4.36 per share, reflecting market concerns regarding the company's financial health and future outlook.
Globenewswire
7.0
03-17Globenewswire
Nuvation Bio Under Investigation for Securities Fraud
  • Investigation Launched: Pomerantz LLP is investigating Nuvation Bio Inc. for potential securities fraud by the company and certain officers, which could significantly impact investor rights and confidence.
  • Earnings Report Insights: On March 2, 2026, Nuvation reported its Q4 and full-year 2025 financial results, revealing that approximately 75% of treatment discontinuations occurred among later-line patient populations, indicating a trend that may adversely affect near-term revenue.
  • Product Launch Challenges: During the commercial launch of IBTROZI (taletrectinib), management noted that a significant share of early patient starts occurred in the third-line or later treatment settings, contributing to a gap between patient initiation and net product revenue growth, which could hinder overall financial performance.
  • Stock Price Reaction: Following this news, Nuvation's stock price fell by $1.48, or 25.3%, closing at $4.36 per share on March 3, 2026, reflecting market concerns regarding the company's future outlook.
PRnewswire
9.0
03-17PRnewswire
IBTROZI Shows Unprecedented Durability in ROS1+ Lung Cancer Treatment
  • Durability of Efficacy: IBTROZI has demonstrated a median Duration of Response (DOR) of 50 months in TKI-naïve patients with ROS1+ non-small cell lung cancer, showcasing its significant durability in treatment and reinforcing its position in oncology.
  • Clinical Data Update: Upcoming presentations at the 2026 AACR Annual Meeting will highlight data from the TRUST-I and TRUST-II studies, emphasizing the efficacy and safety of IBTROZI in TKI-pretreated patients, which is expected to attract further attention and drive clinical adoption.
  • FDA Approval Context: IBTROZI received FDA approval in June 2025 for the treatment of ROS1+ non-small cell lung cancer, marking a breakthrough in cancer therapy and likely enhancing Nuvation Bio's competitive edge in the market.
  • Future Outlook: Nuvation Bio plans to continue evaluating IBTROZI's efficacy in future clinical studies, particularly in early-stage ROS1+ patients, which is anticipated to provide long-term growth potential for the company.
Newsfilter
9.0
03-17Newsfilter
IBTROZI Shows Unprecedented Durability in ROS1+ Lung Cancer Treatment
  • Durability of Efficacy: IBTROZI has demonstrated a median Duration of Response (DOR) of 50 months in TKI-naïve patients with ROS1+ non-small cell lung cancer, showcasing its significant durability in treatment and reinforcing its position in oncology.
  • Clinical Data Update: Upcoming presentations at the 2026 AACR Annual Meeting will highlight updated data from the TRUST-I and TRUST-II studies, emphasizing the efficacy and safety of IBTROZI in TKI-pretreated patients, which is expected to garner increased clinical interest.
  • FDA Approval Context: IBTROZI received FDA approval in June 2025 for the treatment of ROS1+ non-small cell lung cancer, marking a significant milestone in cancer therapy and is anticipated to enhance the company's market performance moving forward.
  • Future Outlook: Nuvation Bio plans to continue evaluating IBTROZI's efficacy in future clinical studies, particularly in early-stage ROS1+ patients, which is expected to create new growth opportunities for the company.
Wall Street analysts forecast NUVB stock price to rise
10 Analyst Rating
Wall Street analysts forecast NUVB stock price to rise
9 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
8.00
Averages
11.38
High
18.00
Current: 0.000
sliders
Low
8.00
Averages
11.38
High
18.00
UBS
Neutral
downgrade
$10 -> $7
AI Analysis
2026-03-03
Reason
UBS
Price Target
$10 -> $7
AI Analysis
2026-03-03
downgrade
Neutral
Reason
UBS lowered the firm's price target on Nuvation Bio to $7 from $10 and keeps a Neutral rating on the shares.
RBC Capital
Outperform
maintain
$12 -> $13
2026-03-03
Reason
RBC Capital
Price Target
$12 -> $13
2026-03-03
maintain
Outperform
Reason
RBC Capital raised the firm's price target on Nuvation Bio to $13 from $12 and keeps an Outperform rating on the shares after its Q4 results. The company's launch of Ibtrozi continues to show promise - with physicians using increasing amounts of the drug in their ROS1 patients driven by good tolerability and high efficacy, the analyst tells investors in a research note. With an over $650M Ibtrozi opportunity, and even greater long-term upside potential on safu, shares are undervaluing the two pillars of the company, the firm added.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for NUVB
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Valuation Metrics

The current forward P/E ratio for Nuvation Bio Inc (NUVB.N) is -15.02, compared to its 5-year average forward P/E of -7.93. For a more detailed relative valuation and DCF analysis to assess Nuvation Bio Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-7.93
Current PE
-15.02
Overvalued PE
-1.52
Undervalued PE
-14.34

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.00
Undervalued EV/EBITDA
0.00

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
47.83
Current PS
19.10
Overvalued PS
236.24
Undervalued PS
-140.58

Financials

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Whales Holding NUVB

G
Greenlight Capital, Inc.
Holding
NUVB
+1.74%
3M Return
T
Tang Capital Management, LLC
Holding
NUVB
-0.90%
3M Return
A
Abrams Capital Management, L.P.
Holding
NUVB
-15.64%
3M Return

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Frequently Asked Questions

What is Nuvation Bio Inc (NUVB) stock price today?

The current price of NUVB is 4.42 USD — it has increased 0.91

What is Nuvation Bio Inc (NUVB)'s business?

Nuvation Bio Inc. is a global biopharmaceutical company. The Company is engaged in tackling the unmet needs in oncology by developing differentiated and therapeutic candidates. Its programs include taletrectinib (ROS1 inhibitor), safusidenib (mIDH1 inhibitor), NUV-1511 (drug-drug conjugate), and NUV-868 (BET inhibitor). The Company's Taletrectinib is an oral, potent, central nervous system-active, selective, ROS1 inhibitor specifically designed for the treatment of patients with ROS1-positive (ROS1+) non-small cell lung cancer (NSCLC). Safusidenib is a novel, oral, potent, brain penetrant, targeted inhibitor of mutant isocitrate dehydrogenase 1(mIDH1). NUV-1511, a clinical-stage drug-drug conjugate (DDC), fuses a targeting agent to a widely used chemotherapy agent. Its NUV-868 is a BD2-selective, oral, small molecule bromodomain and extra-terminal (BET) inhibitor that inhibits BRD4.

What is the price predicton of NUVB Stock?

Wall Street analysts forecast NUVB stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for NUVB is11.38 USD with a low forecast of 8.00 USD and a high forecast of 18.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Nuvation Bio Inc (NUVB)'s revenue for the last quarter?

Nuvation Bio Inc revenue for the last quarter amounts to 41.87M USD, increased 633.06

What is Nuvation Bio Inc (NUVB)'s earnings per share (EPS) for the last quarter?

Nuvation Bio Inc. EPS for the last quarter amounts to -0.11 USD, decreased -26.67

How many employees does Nuvation Bio Inc (NUVB). have?

Nuvation Bio Inc (NUVB) has 298 emplpoyees as of March 27 2026.

What is Nuvation Bio Inc (NUVB) market cap?

Today NUVB has the market capitalization of 1.52B USD.