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INSM Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
143.685
Open
142.420
VWAP
142.71
Vol
407.53K
Mkt Cap
31.19B
Low
140.770
Amount
58.16M
EV/EBITDA(TTM)
--
Total Shares
215.85M
EV
30.48B
EV/OCF(TTM)
--
P/S(TTM)
47.39
Insmed Incorporated is a global biopharmaceutical company. It is advancing a diverse range of approved and mid- to late-stage investigational medicines and drug discovery. Its advanced programs are in pulmonary and inflammatory conditions, including a therapy approved in the United States, Europe, and Japan to treat a chronic, debilitating lung disease. Its pre-clinical research programs encompass a range of technologies and modalities, including gene therapy, AI-driven protein engineering, protein manufacturing, RNA end-joining, and synthetic rescue. Its first commercial product, ARIKAYCE (amikacin liposome inhalation suspension), is used for the treatment of Mycobacterium avium complex lung disease as part of a combination antibacterial drug regimen for adult patients with limited or no alternative treatment options. Its pipeline includes clinical-stage programs, brensocatib, TPIP, and INS1201 and pre-clinical research programs. Its INS1148 is an investigational monoclonal antibody.
Show More

Events Timeline

(ET)
2026-04-07
16:40:00
Insmed Trading Resumes
select
2026-04-07
16:40:00
Insmed Stock Falls 2% to $160 Following Resumption of Trade
select

News

seekingalpha
2.0
04-08seekingalpha
Insmed Halts Lung Disorder Therapy R&D Program After Trial Failure
  • R&D Program Halted: Insmed announced the suspension of its lung disorder therapy brensocatib's R&D following a mid-stage trial failure against hidradenitis suppurativa, indicating that the drug did not meet primary or secondary efficacy endpoints, which could impact the company's future product pipeline.
  • Trial Results Underwhelming: In the Phase 2b CEDAR study, both 10 mg and 40 mg doses failed to meet key goals, although patients tolerated the experimental therapy well with no new safety signals, potentially shaking investor confidence in the company's R&D capabilities.
  • Contribution to Scientific Understanding: Despite the disappointing results, Insmed's medical chief, Martina Flammer, expressed hope that insights gained from this study will contribute to the broader scientific understanding of hidradenitis suppurativa, demonstrating the company's ongoing commitment to scientific research.
  • Market Reaction: The suspension of this R&D program may negatively affect Insmed's stock price, especially after the company secured approval for brensocatib as a treatment for non-cystic fibrosis bronchiectasis in 2025, leading investors to reassess the company's market outlook.
Yahoo Finance
9.0
04-08Yahoo Finance
Insmed Halts Brinsupri Development for HS After Trial Failure
  • Trial Failure: Insmed has halted the development of Brinsupri for hidradenitis suppurativa (HS) after it failed to meet efficacy endpoints in a mid-stage trial, with both 10mg and 40mg doses not outperforming placebo, indicating significant challenges for the company's future R&D direction.
  • Efficacy Data Disclosure: The CEDAR study revealed that Brinsupri achieved only a 45.5% and 40.3% reduction in abscess and nodule counts, respectively, compared to a 57.1% reduction in the placebo group, failing to meet both primary and secondary endpoints, which poses a substantial challenge to Insmed's market confidence.
  • Market Expansion Setback: Despite receiving approval in 2025 for non-cystic fibrosis bronchiectasis, this failure may hinder Brinsupri's expansion plans in the HS market, as analysts believe there is insufficient preclinical evidence to support the drug's mechanism of action in HS.
  • Analyst Sentiment: Analysts generally believe that the trial results will not significantly impact investor sentiment towards Insmed, instead shifting focus to Brinsupri's market performance in bronchiectasis, with projections indicating potential sales of $5.5 billion by 2031.
NASDAQ.COM
9.0
04-08NASDAQ.COM
Insmed Discontinues Brensocatib Development After Phase 2b Study Fails
  • Clinical Trial Results: Insmed Inc. announced that its Phase 2b CEDAR study evaluating brensocatib for moderate to severe hidradenitis suppurativa failed to meet primary and secondary efficacy endpoints in both the 10 mg and 40 mg treatment arms, leading to the discontinuation of the drug's development, indicating limited market prospects for this indication.
  • Safety Profile: Despite the lack of efficacy, brensocatib was well tolerated across both doses with no new safety signals identified, particularly in the 40 mg arm, which may provide a foundation for potential development in other indications in the future.
  • Efficacy Comparison: At Week 16, participants in the 10 mg arm experienced a 45.5% reduction in total abscess and inflammatory nodule (AN) count, while the 40 mg arm saw a 40.3% reduction; in contrast, the placebo group recorded a 57.1% reduction, highlighting brensocatib's inability to outperform placebo, which affects its competitive position in the market.
  • Stock Price Reaction: Insmed's stock closed at $163.03 on Tuesday, down $0.78 (0.48%), but rose to $166.52 in after-hours trading, an increase of $3.49 (2.14%), reflecting cautious optimism among investors regarding the company's future developments.
PRnewswire
9.0
04-07PRnewswire
Insmed Discontinues Brensocatib HS Program After Phase 2b Study Fails
  • Clinical Trial Failure: Insmed announced that its Phase 2b CEDAR study of brensocatib for moderate to severe hidradenitis suppurativa did not meet primary or secondary efficacy endpoints, leading to the decision to discontinue the program, highlighting significant R&D challenges in this area.
  • Stable Safety Profile: Despite the lack of efficacy, brensocatib was well tolerated across both the 10 mg and 40 mg doses, with no new safety signals identified, indicating that the drug maintains a certain potential in terms of safety.
  • Patient Response Data: In the 16-week study, the brensocatib 10 mg and 40 mg groups experienced reductions of 45.5% and 40.3% in total abscess and inflammatory nodule counts, respectively, compared to a 57.1% reduction in the placebo group, demonstrating some symptomatic improvement but insufficient to justify further development.
  • Future Research Directions: Insmed intends to present the data from the CEDAR study at future congresses, and while the results are disappointing, the company hopes that insights gained will contribute to the broader scientific understanding of hidradenitis suppurativa.
stocktwits
9.0
04-07stocktwits
Insmed's Investigational Treatment for Skin Disease Falls Short in Clinical Trial
  • Trial Results: Insmed's mid-stage study evaluating brensocatib in adult patients with moderate to severe hidradenitis suppurativa failed to meet its primary and secondary endpoints.

  • Drug Tolerance: Despite the trial's failure, the drug was reported to be well tolerated among participants.

  • Future Development: Insmed announced plans to discontinue the development of brensocatib for hidradenitis suppurativa.

  • Condition Overview: Hidradenitis suppurativa is a chronic, non-contagious inflammatory skin condition characterized by painful, recurring lumps and abscesses.

moomoo
9.0
04-07moomoo
INSMED INC - PHASE 2B CEDAR STUDY OF BRENSOCATIB FAILED TO ACHIEVE EFFICACY GOALS
  • Study Findings: The study on Bren's catib did not meet the expected efficacy endpoints.
  • Implications: The results may impact future research and development in the relevant field.
Wall Street analysts forecast INSM stock price to rise
19 Analyst Rating
Wall Street analysts forecast INSM stock price to rise
18 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
162.00
Averages
219.50
High
263.00
Current: 0.000
sliders
Low
162.00
Averages
219.50
High
263.00
Guggenheim
Buy
maintain
$227 -> $230
AI Analysis
2026-04-16
New
Reason
Guggenheim
Price Target
$227 -> $230
AI Analysis
2026-04-16
New
maintain
Buy
Reason
Guggenheim raised the firm's price target on Insmed to $230 from $227 and keeps a Buy rating on the shares. The firm adjusted estimates as part of a Q1 earnings preview for commercial-stage companies in its biotechnology coverage.
RBC Capital
Outperform
maintain
$212 -> $216
2026-04-14
Reason
RBC Capital
Price Target
$212 -> $216
2026-04-14
maintain
Outperform
Reason
RBC Capital raised the firm's price target on Insmed to $216 from $212 and keeps an Outperform rating on the shares. The firm has run a survey of 50 physicians to better understand their initial experience using Brinsupri, and expectations for future prescribing. The findings saw that physicians liked Brinsupri's profile and expected to use more of the drug, and importantly, saw the potentially eligible population expanding dramatically, the analyst tells investors in a research note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for INSM
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Valuation Metrics

The current forward P/E ratio for Insmed Inc (INSM.O) is 16.37, compared to its 5-year average forward P/E of -9.44. For a more detailed relative valuation and DCF analysis to assess Insmed Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-9.44
Current PE
16.37
Overvalued PE
1.44
Undervalued PE
-20.31

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-12.12
Current EV/EBITDA
-11.78
Overvalued EV/EBITDA
-2.31
Undervalued EV/EBITDA
-21.92

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
17.99
Current PS
10.99
Overvalued PS
29.29
Undervalued PS
6.69

Financials

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INSM logo
INSM
Insmed Inc
33.34B

Whales Holding INSM

S
Summit Partners Public Asset Management, LLC
Holding
INSM
+27.51%
3M Return
H
Hood River Capital Management LLC
Holding
INSM
+16.06%
3M Return
G
GW&K Investment Management, LLC
Holding
INSM
+14.40%
3M Return
A
Affinity Asset Advisors, LLC
Holding
INSM
+10.72%
3M Return
S
Sofinnova Investment, Inc.
Holding
INSM
+9.18%
3M Return
T
Tang Capital Management, LLC
Holding
INSM
+7.70%
3M Return

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Frequently Asked Questions

What is Insmed Inc (INSM) stock price today?

The current price of INSM is 143.67 USD — it has decreased -0.56

What is Insmed Inc (INSM)'s business?

Insmed Incorporated is a global biopharmaceutical company. It is advancing a diverse range of approved and mid- to late-stage investigational medicines and drug discovery. Its advanced programs are in pulmonary and inflammatory conditions, including a therapy approved in the United States, Europe, and Japan to treat a chronic, debilitating lung disease. Its pre-clinical research programs encompass a range of technologies and modalities, including gene therapy, AI-driven protein engineering, protein manufacturing, RNA end-joining, and synthetic rescue. Its first commercial product, ARIKAYCE (amikacin liposome inhalation suspension), is used for the treatment of Mycobacterium avium complex lung disease as part of a combination antibacterial drug regimen for adult patients with limited or no alternative treatment options. Its pipeline includes clinical-stage programs, brensocatib, TPIP, and INS1201 and pre-clinical research programs. Its INS1148 is an investigational monoclonal antibody.

What is the price predicton of INSM Stock?

Wall Street analysts forecast INSM stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for INSM is219.50 USD with a low forecast of 162.00 USD and a high forecast of 263.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Insmed Inc (INSM)'s revenue for the last quarter?

Insmed Inc revenue for the last quarter amounts to 263.84M USD, increased 152.62

What is Insmed Inc (INSM)'s earnings per share (EPS) for the last quarter?

Insmed Inc. EPS for the last quarter amounts to -1.54 USD, increased 17.56

How many employees does Insmed Inc (INSM). have?

Insmed Inc (INSM) has 1664 emplpoyees as of April 20 2026.

What is Insmed Inc (INSM) market cap?

Today INSM has the market capitalization of 31.19B USD.