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NBIX Should I Buy

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Intellectia

Should You Buy Neurocrine Biosciences Inc (NBIX) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
127.780
1 Day change
-1.36%
52 Week Range
160.180
Analysis Updated At
2026/03/13
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Neurocrine Biosciences Inc (NBIX) is not a strong buy at the moment for a beginner investor with a long-term strategy. While the company shows strong financial growth and positive analyst sentiment, the technical indicators suggest a bearish trend, and there are no immediate positive trading signals or catalysts to justify an entry point right now.

Technical Analysis

The MACD is slightly positive but contracting, RSI is neutral at 34.847, and moving averages are bearish (SMA_200 > SMA_20 > SMA_5). The stock is trading below the pivot level of 130.706, with the nearest support at 127.669 and resistance at 133.743. The pre-market price is 126.78, down 0.78%, indicating bearish momentum.

Options Data

Bearish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

The high open interest put-call ratio suggests bearish sentiment, while the low option volume put-call ratio indicates limited trading activity in puts compared to calls.

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
10
Buy
1

Positive Catalysts

  • Strong financial performance in Q4 2025 with revenue up 28.33% YoY, net income up 49.08% YoY, and EPS up 48.00% YoY. Analysts maintain positive ratings, with JPMorgan, Wolfe Research, and others highlighting strong growth potential for Ingrezza and Crenessity.

Neutral/Negative Catalysts

  • Bearish technical indicators and lack of significant trading trends from hedge funds or insiders. The stock has a 50% chance of declining by -1.46% in the next day and -7.9% in the next month based on historical patterns.

Financial Performance

In Q4 2025, Neurocrine reported strong growth with revenue at $805.5M (+28.33% YoY), net income at $153.7M (+49.08% YoY), and EPS at 1.48 (+48.00% YoY). However, gross margin slightly declined to 97.82% (-0.71% YoY).

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts are generally positive on NBIX, with multiple firms maintaining Buy or Outperform ratings. Price targets range from $140 to $192, with JPMorgan and others highlighting strong growth potential for Ingrezza and Crenessity. However, some firms have slightly lowered price targets following Q4 earnings.

Wall Street analysts forecast NBIX stock price to rise
20 Analyst Rating
Wall Street analysts forecast NBIX stock price to rise
17 Buy
3 Hold
0 Sell
Strong Buy
Current: 129.540
sliders
Low
143
Averages
179.68
High
203
Current: 129.540
sliders
Low
143
Averages
179.68
High
203
JPMorgan
Overweight
maintain
$176 -> $177
AI Analysis
2026-03-12
New
Reason
JPMorgan
Price Target
$176 -> $177
AI Analysis
2026-03-12
New
maintain
Overweight
Reason
JPMorgan raised the firm's price target on Neurocrine to $177 from $176 and keeps an Overweight rating on the shares. The firm increased Crenessity estimates after surveying 25 endocrinologists. JPMorgan is "encouraged" by the survey results which suggest "strong uptake" of Crenessity over the next year across key settings and physician populations.
Wolfe Research
Outperform
initiated
$160
2026-02-23
Reason
Wolfe Research
Price Target
$160
2026-02-23
initiated
Outperform
Reason
Wolfe Research initiated coverage of Neurocrine with an Outperform rating and $160 price target. The firm launched coverage of the neuroscience biotech sector with a "portfolio of high conviction names across multiple therapeutic areas." Wolfe believes the Inflation Reduction Act on Neurocrine's Ingrezza should be modest. It says this already priced into the shares.
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