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MIST Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
1.080
Open
1.030
VWAP
1.03
Vol
2.14M
Mkt Cap
118.84M
Low
1.000
Amount
2.21M
EV/EBITDA(TTM)
--
Total Shares
117.67M
EV
70.08M
EV/OCF(TTM)
--
P/S(TTM)
52.65
Milestone Pharmaceuticals Inc. is a Canada-based biopharmaceutical company. The Company is focused on the development and commercialization of cardiovascular medicines. Its lead product candidate, etripamil, is a potent rapid-onset calcium channel blocker that the Company designed and is developing as a rapid-onset nasal spray to be administered by patients. The Company is also focused on developing etripamil to treat paroxysmal supraventricular tachycardia, atrial fibrillation, and other cardiovascular indications.
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Events Timeline

(ET)
2026-03-20
16:20:00
Major Averages Close Broadly Lower, S&P 500 Down Over 1.5%
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2026-03-20
12:10:00
Major Averages Decline Again as Oil Prices Rise
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2026-03-20
09:00:00
Stock Futures Modestly Lower, Market Sentiment Cautious
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2026-03-20
07:20:00
Milestone Cash and Short-Term Investments Rise to $106M
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2026-03-16 (ET)
2026-03-16
08:20:00
Milestone Pharmaceuticals to Showcase New Treatment at ACC 2026
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2026-02-10 (ET)
2026-02-10
08:30:00
Milestone Appoints David Sandoval as General Counsel
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2026-02-03 (ET)
2026-02-03
08:30:00
Milestone Pharmaceuticals Grants 419,000 Equity Awards
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2026-01-26 (ET)
2026-01-26
08:10:00
Milestone Pharmaceuticals Launches Cardamyst Nasal Spray
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2026-01-06 (ET)
2026-01-06
08:20:00
Milestone Pharmaceuticals Submits MAA for Etripamil Nasal Spray
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News

NASDAQ.COM
9.5
03-23NASDAQ.COM
Milestone Pharmaceuticals Reports Q4 and FY 2025 Results with CARDAMYST Updates
  • Financial Performance: Milestone Pharmaceuticals reported a wider net loss of $17.4 million for Q4 2025, translating to $0.16 per share, compared to a loss of $12.4 million or $0.19 per share in the previous year, indicating financial pressures during the product launch phase.
  • Revenue Source: The company recorded $1.54 million in revenue for Q4 2025 from a milestone payment under its licensing agreement with Corxel Pharmaceuticals, marking an initial success in the commercialization of CARDAMYST following its FDA approval in the U.S.
  • Product Approval and Marketing: CARDAMYST received FDA approval in December 2025 as the first self-administered nasal spray, with a sales team of 60 representatives expected to enhance market penetration in the cardiology sector.
  • Future Plans: Milestone plans to conduct a Phase 3 registrational program to evaluate Etripamil for acute atrial fibrillation control, intending to leverage the initial PSVT indication to facilitate subsequent regulatory approvals.
Newsfilter
9.5
03-20Newsfilter
Milestone Pharmaceuticals Earnings Report Preview
  • Earnings Release Date: Milestone Pharmaceuticals is expected to release its earnings report on March 19, indicating a significant focus from the market on the company's future performance and potential stock movements.
  • Earnings Per Share Forecast: Analysts predict an earnings per share of 16 cents, reflecting the company's profitability in the current market environment, which could influence shareholder confidence and investment decisions.
  • Revenue Expectations: The company is anticipated to generate $1.20 million in revenue, suggesting Milestone's efforts in product promotion and market acceptance, which may lay the groundwork for future growth opportunities.
  • Market Reaction Anticipation: Following the earnings report, investors will closely monitor the actual results against analyst expectations, which will directly impact Milestone Pharmaceuticals' stock price volatility and overall market sentiment.
Yahoo Finance
9.5
03-20Yahoo Finance
Milestone Pharmaceuticals Reports Q4 2025 Earnings and CARDAMYST Launch
  • Revenue and Loss Overview: Milestone Pharmaceuticals reported milestone revenue of $1.5 million in Q4 2025, yet faced a net loss of $63.1 million for the year, translating to a loss of $0.75 per share, highlighting financial pressures during the early market launch phase.
  • CARDAMYST Launch Progress: The company successfully launched CARDAMYST within six weeks of FDA approval, with over 150 prescriptions filled by more than 100 unique prescribers in the first month, indicating a positive initial market reception for the drug.
  • Financial Position and Future Outlook: As of December 31, 2025, Milestone had $106 million in cash and cash equivalents, and with approximately $200 million in pro forma cash raised post-year-end, the company is well-positioned for operations into late 2027, enhancing its competitive stance in the market.
  • Insurance Coverage Challenges: Despite positive feedback for CARDAMYST, the company faces significant delays in insurance coverage, with over half of prescriptions not being filled due to insurer controls, and Medicare coverage is not expected until 2027, which may hinder market penetration.
seekingalpha
9.5
03-20seekingalpha
Milestone Pharmaceuticals Reports FY Results
  • Earnings Report: Milestone Pharmaceuticals reported a FY GAAP EPS of -$0.75, indicating significant challenges in profitability that could undermine investor confidence.
  • Revenue Figures: The company generated revenue of $1.55 million, which, while providing some income, falls short of market expectations, potentially putting downward pressure on the stock price.
  • Market Reaction: Analysts downgraded Milestone to a 'Sell' rating as CARDAMYST faces tough market realities, which may further influence investor sentiment towards the company.
  • Investor Sentiment: Following the approval of Cardamyst, the market's negative reaction suggests that selling news related to Milestone may not be prudent, potentially leading to increased stock price volatility in the short term.
seekingalpha
9.5
03-19seekingalpha
Major Earnings Reports Expected on Friday
  • Earnings Reports: Major companies set to report earnings on Friday include Milestone Pharmaceuticals (MIST), Westwater Resources (WWR), and XPeng (XPEV), which will provide investors with crucial financial data and market outlooks.
  • Market Focus: Investors will closely monitor these earnings reports to assess performance and future growth potential, particularly in the current economic climate where market sensitivity to tech and resource companies is heightened.
  • Industry Impact: XPeng, as an electric vehicle manufacturer, will have its earnings report scrutinized for its potential influence on the overall EV sector, possibly affecting investor confidence and capital flows within the industry.
  • Investor Strategy: With the earnings season approaching, investors may adjust their strategies in response to the upcoming performance data, particularly reevaluating positions in companies that have underperformed in the market.
Newsfilter
5.0
01-26Newsfilter
CARDAMYST Nasal Spray Now Available at Retail Pharmacies
  • Product Launch: Milestone Pharmaceuticals announces that its first commercial product, CARDAMYST™ (etripamil) nasal spray, is now available at U.S. retail pharmacies, marking a significant advancement in the cardiovascular drug market.
  • Sales Force Deployment: The company plans to deploy a national sales force in mid-February 2026 to support product promotion and market penetration, which is expected to significantly enhance market coverage and sales potential.
  • Patient Assistance Program: CARDAMYST will be supported by a comprehensive patient assistance platform offering benefits verification and reimbursement support, with a projected $25 copay cap for eligible commercially insured patients, thereby reducing financial burdens on patients.
  • FDA Approval Milestone: CARDAMYST received FDA approval on December 12, 2025, becoming the first drug approved for treating paroxysmal supraventricular tachycardia (PSVT) in over 30 years, addressing a critical gap in effective treatment options.
Wall Street analysts forecast MIST stock price to rise
3 Analyst Rating
Wall Street analysts forecast MIST stock price to rise
3 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
8.00
Averages
8.00
High
8.00
Current: 0.000
sliders
Low
8.00
Averages
8.00
High
8.00
Wells Fargo
Mohit Bansal
upgrade
$4 -> $8
AI Analysis
2025-12-16
Reason
Wells Fargo
Mohit Bansal
Price Target
$4 -> $8
AI Analysis
2025-12-16
upgrade
Reason
Wells Fargo analyst Mohit Bansal raised the firm's price target on Milestone Pharmaceuticals to $8 from $4 and keeps an Overweight rating on the shares. The firm says Cardamyst's robust label, its reasonable pricing and management's launch strategy bode well for a strong launch. Wells continues to see upside potential to stock despite recent strong performance.
H.C. Wainwright
Brandon Folkes
Buy
upgrade
$5 -> $8
2025-12-15
Reason
H.C. Wainwright
Brandon Folkes
Price Target
$5 -> $8
2025-12-15
upgrade
Buy
Reason
H.C. Wainwright analyst Brandon Folkes raised the firm's price target on Milestone Pharmaceuticals to $8 from $5 and keeps a Buy rating on the shares following the approval of Cardamyst for the treatment of paroxysmal supraventricular tachycardia. The shares at curet levels underappreciate the commercial opportunity of Cardamyst in PSVT, the analyst tells investors in a research note. H.C. Wainwright expects commercial outperformance and the re-initiation of the AFib-RVR trial to drive share momentum over the next 12 to 18 months.
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Valuation Metrics

The current forward P/E ratio for Milestone Pharmaceuticals Inc (MIST.O) is -4.21, compared to its 5-year average forward P/E of -2.82. For a more detailed relative valuation and DCF analysis to assess Milestone Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-2.82
Current PE
-4.21
Overvalued PE
-1.73
Undervalued PE
-3.90

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.91
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
-0.91
Undervalued EV/EBITDA
-2.92

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
47.89
Current PS
5.09
Overvalued PS
140.22
Undervalued PS
-44.44

Financials

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Frequently Asked Questions

What is Milestone Pharmaceuticals Inc (MIST) stock price today?

The current price of MIST is 1.01 USD — it has decreased -2.88

What is Milestone Pharmaceuticals Inc (MIST)'s business?

Milestone Pharmaceuticals Inc. is a Canada-based biopharmaceutical company. The Company is focused on the development and commercialization of cardiovascular medicines. Its lead product candidate, etripamil, is a potent rapid-onset calcium channel blocker that the Company designed and is developing as a rapid-onset nasal spray to be administered by patients. The Company is also focused on developing etripamil to treat paroxysmal supraventricular tachycardia, atrial fibrillation, and other cardiovascular indications.

What is the price predicton of MIST Stock?

Wall Street analysts forecast MIST stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for MIST is8.00 USD with a low forecast of 8.00 USD and a high forecast of 8.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Milestone Pharmaceuticals Inc (MIST)'s revenue for the last quarter?

Milestone Pharmaceuticals Inc revenue for the last quarter amounts to 1.55M USD, decreased

What is Milestone Pharmaceuticals Inc (MIST)'s earnings per share (EPS) for the last quarter?

Milestone Pharmaceuticals Inc. EPS for the last quarter amounts to -0.16 USD, decreased -15.79

How many employees does Milestone Pharmaceuticals Inc (MIST). have?

Milestone Pharmaceuticals Inc (MIST) has 38 emplpoyees as of March 31 2026.

What is Milestone Pharmaceuticals Inc (MIST) market cap?

Today MIST has the market capitalization of 118.84M USD.