Loading...

Intellectia LogoIntellectia
AI Trading Bot
Features
Markets
News
Resources
Pricing
  1. Home
  2. Stock
  3. TSHA
TSHA logo

TSHA Overview

-
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
OverviewStock Price PredictionTechnicalValuationFinancialsEarningsShould I BuyNews & Events
an image of Intellectia Logoan image of Intellectia

Most Trusted AI Platform for Winning Trades

TwitterYoutubeQuoraDiscordLinkedinTelegram

Copyright © 2026 Intellectia.AI. All Rights Reserved.

Company

  • Home
  • Contact
  • About Us
  • Press
  • Privacy
  • Terms of Service
  • Service Terms of Use

Resources

  • Blog
  • Tutorial
  • Help Center
  • Affiliate Program

Markets

  • Market Analysis
  • Crypto
  • Featured Screeners
  • AI Earnings Calendar
  • Market Movers
  • Stock Monitor
  • Economic Calendar
  • All US Stocks
  • All Cryptos

Tools

  • Dividend Calculator
  • Dividend Yield Calculator
  • Options Profit Calculator

Features

  • QuantAI Alpha Pick
  • SwingMax Portfolio
  • Swing Trading
  • AI Stock Picker
  • Whales Auto Tracker
  • Daytrading Center
  • Patterns Detection
  • AI Screener
  • Financial AI Agent
  • Backtesting Playground
  • AI Earnings Prediction
  • Stock Monitor
  • Technical Analysis

News

  • Overview
  • Top News
  • Daily Market Brief
  • Earnings Analysis
  • Newswire
  • Stock News
  • Crypto News
  • Institution News
  • Congress News
  • Monitor News

Compare

  • TradingView
  • SeekingAlpha
Intellectia

Loading chart...

High
4.700
Open
4.700
VWAP
4.60
Vol
1.41M
Mkt Cap
1.25B
Low
4.525
Amount
6.47M
EV/EBITDA(TTM)
--
Total Shares
273.92M
EV
1.01B
EV/OCF(TTM)
--
P/S(TTM)
216.22
Taysha Gene Therapies Inc is a clinical-stage biotechnology company, which is focused on advancing adeno-associated virus (AAV)-based gene therapies for severe monogenic diseases of the central nervous system. The Company’s lead clinical program, TSHA-102, is in development for the treatment of Rett syndrome, a rare neurodevelopmental disorder. The Company is evaluating TSHA-102 in the REVEALPhase I/II adolescent and adult clinical trial, which is a first-in-human, open-label, randomized, dose escalation and dose-expansion, multicenter study evaluating the safety and preliminary efficacy of TSHA-102 in female patients aged 12-years and older with Rett syndrome. It has acquired a worldwide right to a clinical-stage, intrathecally dosed AAV9 gene therapy program, TSHA-120, for the treatment of giant axonal neuropathy (GAN). TSHA-105 is a gene replacement therapy in development for the treatment of SLC13A5 deficiency, a rare autosomal recessive epileptic encephalopathy.
Show More

Events Timeline

(ET)
2026-03-06
08:10:00
Taysha Gene Therapies Grants New Employee RSUs and Options
select
2026-02-06 (ET)
2026-02-06
08:10:00
Taysha Gene Therapies Grants 349,000 Restricted Stock Units to New Employees
select
2026-01-06 (ET)
2026-01-06
08:20:00
Taysha Gene Therapies TSHA-102 Program Progress Announced
select
2025-11-11 (ET)
2025-11-11
16:27:07
Richard Pazdur Named Director of CDER by FDA
select
link

News

CNBC
9.0
03-06CNBC
FDA Rejects Multiple Experimental Drug Applications, Raising Investor Concerns
  • FDA Drug Rejections: The U.S. FDA has denied or discouraged applications for at least eight drugs over the past year, including UniQure's gene therapy for Huntington's disease, indicating regulatory uncertainty that could impact future treatment approvals.
  • Investor Concerns Rise: Investors are increasingly wary as the FDA appears to change its standards for drug applications, particularly for treatments targeting hard-to-treat diseases, leading to diminished confidence in ongoing development efforts.
  • Changing Regulatory Standards: The FDA's request for UniQure to conduct new placebo-controlled trials contradicts previous guidance, highlighting inconsistencies in the agency's approval process that may create uncertainty for companies in their R&D efforts.
  • Uncertain Future Outlook: Analysts warn that if the FDA does not approve Denali Therapeutics' drug for Hunter syndrome, it could further undermine other companies' confidence in running open-label studies, potentially stifling innovation across the industry.
Newsfilter
7.0
03-06Newsfilter
FDA Drug Approval Uncertainty Intensifies
  • Drug Applications Denied: According to RTW Investments, the FDA has denied or discouraged applications for at least eight new drugs over the past year, including gene therapies for Huntington's and Hunter syndrome, raising investor concerns about the prospects for other drugs in the pipeline.
  • Changing Regulatory Standards: The FDA's request for UniQure to conduct new placebo-controlled studies contradicts previous guidance, leading investors to doubt the agency's consistency and fearing that this could jeopardize future treatment approvals.
  • Negative Market Reaction: Stocks of several biotech companies have declined following FDA rejections, with analysts noting a stark conflict between the FDA's recent decisions and the flexibility promised by its leadership, causing investors to lose confidence in companies relying on FDA leniency.
  • Uncertain Future Outlook: Although FDA officials assert that biomarkers can lead to accelerated approvals, investors remain confused about the agency's approval standards, particularly for drugs targeting rare diseases, making future approval pathways increasingly uncertain.
Globenewswire
2.0
01-06Globenewswire
Taysha Gene Therapies Doses First Patient in TSHA-102 Pivotal Trial for Rett Syndrome
  • Trial Progress: Taysha Gene Therapies successfully dosed the first patient in the TSHA-102 pivotal trial in Q4 2025, with plans to complete dosing for all 15 patients by Q2 2026, marking a significant milestone in the treatment of Rett syndrome.
  • FDA Alignment: The company reached written alignment with the FDA to include three months of safety data from the ASPIRE trial in its planned BLA submission, aiming to enable broad labeling for patients aged two and older, which will expedite the path to market.
  • Market Opportunity: With an estimated 15,000 to 20,000 patients affected by Rett syndrome across the U.S., EU, and U.K., Taysha aims to redefine the treatment paradigm for this high unmet need disease through compelling clinical data from TSHA-102, presenting a significant market opportunity.
  • Long-term Data Update: An update on long-term safety and efficacy data from the REVEAL trial is expected in H1 2026, which will provide crucial support for the company's future treatment strategies and enhance its competitive position in the market.
Globenewswire
5.0
2025-12-05Globenewswire
Taysha Grants 212,000 Stock Options to New Employees
  • Employee Incentive Program: On December 3, 2025, Taysha Gene Therapies granted 212,000 stock options to two new employees at an exercise price of $4.49 per share, aimed at attracting and retaining key talent, thereby enhancing the company's competitive edge in the gene therapy sector.
  • Option Structure: These options will be valid for 10 years and vest over four years, with 25% vesting on the first anniversary and the remaining 75% vesting in equal monthly installments over the subsequent 36 months, ensuring continued employee contributions during their tenure.
  • Compliance Assurance: The stock option grant complies with Nasdaq Listing Rule 5635(c)(4), demonstrating the company's commitment to transparency and compliance in talent acquisition, which can bolster investor confidence.
  • Strategic Goals: Taysha focuses on developing gene therapies for severe monogenic diseases, particularly its clinical program TSHA-102 for Rett syndrome, and aims to accelerate research and development through these incentive measures to address unmet medical needs.
SeekingAlpha
6.0
2025-12-04SeekingAlpha
Goldman Sachs Upgrades Taysha Gene Therapies Due to Progress in Rett Syndrome Treatment
  • Goldman Sachs Upgrade: Goldman Sachs has upgraded Taysha Gene Therapies (TSHA) to a buy rating, citing progress with its Rett syndrome candidate TSHA-102, which has moved into phase 3 trials.

  • Price Target and Market Potential: The investment bank set a price target of $11, indicating a potential upside of approximately 145%, and estimates global peak sales for TSHA-102 could reach $3 billion.

  • Positive Analyst Outlook: Analyst Salveen Richter expressed optimism about the late-stage trial results, noting that TSHA-102 is differentiated from competitor Neurogene's gene therapy based on clinical and safety data.

  • Recent Stock Performance: Taysha's stock has seen an increase of about 11% in trading, reflecting positive market sentiment following the upgrade and developments in their clinical trials.

Yahoo Finance
5.0
2025-12-02Yahoo Finance
Insider at Taysha Gene Therapies Sells Shares Valued at $1,695,906, Recent SEC Filing Reveals
  • Leadership Role: Sukumar Nagendran serves as the Director, President, and Head of Research & Development.

  • Date of Announcement: The information was shared on November 28, 2025.

Wall Street analysts forecast TSHA stock price to rise
11 Analyst Rating
Wall Street analysts forecast TSHA stock price to rise
11 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
8.00
Averages
11.60
High
19.00
Current: 0.000
sliders
Low
8.00
Averages
11.60
High
19.00
Wells Fargo
Zachary Fadem
Overweight
maintain
$8 -> $11
AI Analysis
2026-01-05
Reason
Wells Fargo
Zachary Fadem
Price Target
$8 -> $11
AI Analysis
2026-01-05
maintain
Overweight
Reason
Wells Fargo analyst Zachary Fadem raised the firm's price target on Taysha Gene Therapies to $11 from $8 and keeps an Overweight rating on the shares. The firm sees another year of outperformance for the stock, driven by continued momentum in the company's pivotal Rett syndrome study following last year's alignment with FDA on a favorable design.
Goldman Sachs
Salveen Richter
Early-Stage Biotech -> Buy
upgrade
$11
2025-12-04
Reason
Goldman Sachs
Salveen Richter
Price Target
$11
2025-12-04
upgrade
Early-Stage Biotech -> Buy
Reason
Goldman Sachs analyst Salveen Richter moved its rating on Taysha Gene Therapies to Buy with an $11 price target from Early-Stage Biotech designation. The firm is positive on the company's outlook in Rett syndrome. believe Taysha can achieve the response rate of 33% needed to meet the minimum threshold for success in the REVEAL study, the analyst tells investors in a research note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for TSHA
Unlock Now

Valuation Metrics

The current forward P/E ratio for Taysha Gene Therapies Inc (TSHA.O) is -12.62, compared to its 5-year average forward P/E of -4.38. For a more detailed relative valuation and DCF analysis to assess Taysha Gene Therapies Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.38
Current PE
-12.62
Overvalued PE
-1.47
Undervalued PE
-7.30

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.01
Current EV/EBITDA
-8.60
Overvalued EV/EBITDA
-0.72
Undervalued EV/EBITDA
-5.31

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
46.36
Current PS
268.10
Overvalued PS
106.83
Undervalued PS
-14.10

Financials

AI Analysis
Annual
Quarterly

Related Community Screener

top 5 penny stocks?
Intellectia · 91 candidates
Market Cap: 50.00M - 2.00BRegion: USPrice: $0.10 - $5.00List Exchange: XNYS, XNAS, XASEMoving Average Relationship: PriceAboveMA20Month Price Change Pct: $0.00 - $150.00Monthly Average Dollar Volume: >= 500,000
Ticker
Name
Market Cap$
top bottom
RXT logo
RXT
Rackspace Technology Inc
409.23M
KOS logo
KOS
Kosmos Energy Ltd
1.03B
IOVA logo
IOVA
Iovance Biotherapeutics Inc
1.14B
GERN logo
GERN
Geron Corp
1.20B
TRX logo
TRX
TRX Gold Corp
516.12M
AQST logo
AQST
Aquestive Therapeutics Inc
481.91M
Best stocks under $5
Intellectia · 498 candidates
Price: $0.50 - $5.00Volume: >= 200,000Market Cap Category: small, micro, nanoList Exchange: XNYS, XNAS, XASE
Ticker
Name
Market Cap$
top bottom
NWL logo
NWL
Newell Brands Inc
1.97B
RXRX logo
RXRX
Recursion Pharmaceuticals Inc
1.82B
PTON logo
PTON
Peloton Interactive Inc
1.81B
BBAI logo
BBAI
BigBear.ai Holdings Inc
1.78B
TV logo
TV
Grupo Televisa SAB
1.77B
FUBO logo
FUBO
FuboTV Inc
1.74B
best penny stock to buy tomorrow
Intellectia · 90 candidates
Market Cap: 50.00M - 1.50BRegion: USPrice: $0.50 - $5.00List Exchange: XNYS, XNAS, XASEWeek Price Change Pct: $5.00 - $50.00One Day Rise Prob: 0 - 100One Day Predict Return: 0.0% - 100.0%Monthly Average Dollar Volume: >= 300,000
Ticker
Name
Market Cap$
top bottom
CRBU logo
CRBU
Caribou Biosciences Inc
148.61M
HUYA logo
HUYA
HUYA Inc
1.03B
BYND logo
BYND
Beyond Meat Inc
321.54M
CABA logo
CABA
Cabaletta Bio Inc
247.40M
TSHA logo
TSHA
Taysha Gene Therapies Inc
1.28B
ATOM logo
ATOM
Atomera Inc
77.94M
most bullish ticker
Intellectia · 46 candidates
Analyst Consensus: Strong BuyTarget Price Upside Potential: MoreAbovePriceMoving Average Relationship: PriceAboveMA200Option Sentiments: BullishOne Week Rise Prob: >= 70
Ticker
Name
Market Cap$
top bottom
TARS logo
TARS
Tarsus Pharmaceuticals Inc
2.78B
DERM logo
DERM
Journey Medical Corp
276.86M
CYTK logo
CYTK
Cytokinetics Inc
7.93B
ABCL logo
ABCL
Abcellera Biologics Inc
1.19B
SVRA logo
SVRA
Savara Inc
1.16B
TSHA logo
TSHA
Taysha Gene Therapies Inc
1.29B
I want to buy penny stock
Intellectia · 182 candidates
Market Cap: <= 2.00BPrice: <= $5.00Beta: HighRiskWeekly Average Turnover: >= 1,000,000Is Optionable: True
Ticker
Name
Market Cap$
top bottom
MQ logo
MQ
Marqeta Inc
1.94B
CLVT logo
CLVT
Clarivate PLC
1.86B
NWL logo
NWL
Newell Brands Inc
1.79B
TV logo
TV
Grupo Televisa SAB
1.74B
BITF logo
BITF
Bitfarms Ltd
1.61B
PGEN logo
PGEN
Precigen Inc
1.58B

Whales Holding TSHA

A
Artal Group S.A.
Holding
TSHA
+7.70%
3M Return
V
Vestal Point Capital, LP
Holding
TSHA
+6.94%
3M Return
R
RA Capital Management, L.P.
Holding
TSHA
+4.57%
3M Return
A
Avoro Capital Advisors LLC
Holding
TSHA
-2.32%
3M Return
B
Baker Bros. Advisors LP
Holding
TSHA
-3.94%
3M Return

Trading Trends

    Insider
    Hedge Fund
    Congress Trading

People Also Watch

Frequently Asked Questions

What is Taysha Gene Therapies Inc (TSHA) stock price today?

The current price of TSHA is 4.57 USD — it has decreased -0.44

What is Taysha Gene Therapies Inc (TSHA)'s business?

Taysha Gene Therapies Inc is a clinical-stage biotechnology company, which is focused on advancing adeno-associated virus (AAV)-based gene therapies for severe monogenic diseases of the central nervous system. The Company’s lead clinical program, TSHA-102, is in development for the treatment of Rett syndrome, a rare neurodevelopmental disorder. The Company is evaluating TSHA-102 in the REVEALPhase I/II adolescent and adult clinical trial, which is a first-in-human, open-label, randomized, dose escalation and dose-expansion, multicenter study evaluating the safety and preliminary efficacy of TSHA-102 in female patients aged 12-years and older with Rett syndrome. It has acquired a worldwide right to a clinical-stage, intrathecally dosed AAV9 gene therapy program, TSHA-120, for the treatment of giant axonal neuropathy (GAN). TSHA-105 is a gene replacement therapy in development for the treatment of SLC13A5 deficiency, a rare autosomal recessive epileptic encephalopathy.

What is the price predicton of TSHA Stock?

Wall Street analysts forecast TSHA stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for TSHA is11.60 USD with a low forecast of 8.00 USD and a high forecast of 19.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Taysha Gene Therapies Inc (TSHA)'s revenue for the last quarter?

Taysha Gene Therapies Inc revenue for the last quarter amounts to 0.00 USD, decreased -100.00

What is Taysha Gene Therapies Inc (TSHA)'s earnings per share (EPS) for the last quarter?

Taysha Gene Therapies Inc. EPS for the last quarter amounts to -0.09 USD, decreased -10.00

How many employees does Taysha Gene Therapies Inc (TSHA). have?

Taysha Gene Therapies Inc (TSHA) has 73 emplpoyees as of March 11 2026.

What is Taysha Gene Therapies Inc (TSHA) market cap?

Today TSHA has the market capitalization of 1.25B USD.