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IRWD Overview

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$
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0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
3.670
Open
3.630
VWAP
3.58
Vol
2.04M
Mkt Cap
587.67M
Low
3.495
Amount
7.29M
EV/EBITDA(TTM)
4.70
Total Shares
164.61M
EV
956.99M
EV/OCF(TTM)
8.53
P/S(TTM)
1.60
Ironwood Pharmaceuticals, Inc. is a biotechnology company developing and commercializing life-changing therapies for people living with gastrointestinal (GI), and rare diseases. It is focused on the development and commercialization of GI product opportunities in areas of significant unmet need. LINZESS (linaclotide), its commercial product, is indicated for adult men and women suffering from irritable bowel syndrome with constipation (IBS-C), or chronic idiopathic constipation (CIC), and for pediatric patients ages 6-17 years-old suffering from functional constipation (FC). Linaclotide is available under the trademarked name CONSTELLA to adult men and women suffering from IBS-C or CIC and pediatric patients. The Company is also engaged in advancing apraglutide, a synthetic long-acting peptide analog of glucagon-like peptide-2 (GLP-2), for short bowel syndrome (SBS), patients who are dependent on parenteral support.
Show More

Events Timeline

(ET)
2026-05-27
10:10:00
Ironwood Receives FDA Approval for Linzess in Children Aged 2 and Older
select
2026-05-18 (ET)
2026-05-18
08:10:00
Kyverna Therapeutics Appoints Greg Martini as CFO
select
2026-05-07 (ET)
2026-05-07
07:20:00
Ironwood Reports Q1 Revenue of $106.5M, Beating Consensus
select
2026-05-07
07:20:00
Affirms 2026 Adjusted EBITDA View of Over $300M
select
2026-02-25 (ET)
2026-02-25
08:00:00
Company Expects FY26 Adjusted EBITDA of At Least $300M
select
2026-02-25
08:00:00
Ironwood Q4 Revenue at $47.71M, Below Expectations
select

News

NASDAQ.COM
9.0
05-28NASDAQ.COM
PinnedFDA Approves LINZESS for Pediatric Functional Constipation Treatment
  • FDA Approval: Ironwood Pharmaceuticals announced that its drug LINZESS has received FDA approval for the treatment of functional constipation in children aged 2 and older, marking a significant expansion into the pediatric market.
  • Clinical Trial Support: The approval was supported by a 12-week Phase 3 randomized controlled trial demonstrating significant improvement in spontaneous bowel movements in children aged 2 to 5, with a favorable safety profile, enhancing its competitive edge in the market.
  • Market Potential: Functional constipation is common among preschool-aged children, with a global prevalence of over 3%, and the approval of LINZESS is expected to provide new treatment options for over 5.5 million patients, addressing unmet medical needs.
  • Stock Price Dynamics: Despite the approval, Ironwood's stock price fell by 4.87% to $3.71 at Wednesday's close, indicating a cautious market reaction to the news, necessitating close monitoring of future stock performance.
NASDAQ.COM
8.5
05-29NASDAQ.COM
Regulatory Approvals and Collaborations in Biotech Sector
  • FDA Approval for AZN: AstraZeneca (AZN) secured FDA approval for the IMFINZI + BCG combination in high-risk non-muscle-invasive bladder cancer, supported by Phase 3 POTOMAC data showing a 32% reduction in recurrence or death, enhancing its competitive edge in oncology.
  • JNJ TREMFYA Label Expansion: Johnson & Johnson (JNJ) received FDA approval to add structural joint-damage inhibition data to the TREMFYA label for active psoriatic arthritis, confirming its unique position in first-line treatment with no new safety signals, reinforcing its market leadership.
  • LINZESS Approved for Children: Ironwood Pharmaceuticals (IRWD) gained FDA approval for LINZESS to treat functional constipation in children aged 2-5, based on a 12-week Phase 3 trial showing significant improvement in spontaneous bowel movements, expanding its pediatric market influence.
  • AbbVie's DECNUPAZ Approval: AbbVie (ABBV) received FDA approval for DECNUPAZ to treat ultra-rare blood cancer BPDCN, supported by Phase 1 data showing a 69.7% composite complete response rate and a median duration of 9.7 months, marking a significant innovation in hematologic oncology.
seekingalpha
8.5
05-27seekingalpha
FDA Approves Linzess Label Expansion for Children
  • Label Expansion: The FDA's approval for Linzess to treat functional constipation in children aged two and older significantly broadens its application, likely increasing market demand and sales potential in the pediatric segment.
  • Clinical Trial Evidence: This approval is supported by a 12-week Phase 3 trial demonstrating that Linzess at a 72 mcg dose significantly improved spontaneous bowel movement frequency compared to placebo, while maintaining a tolerability profile consistent with its established safety record.
  • Market Partnerships: Ironwood collaborates with AbbVie for marketing Linzess in the U.S. and Europe, and with Astellas in Japan, enhancing its global market presence and competitive edge in the pharmaceutical industry.
  • Focus on Pediatric Health: Given the prevalence of functional constipation among preschool children, this label expansion not only addresses a critical healthcare need but also positions Ironwood for further growth in the pediatric pharmaceutical market, enhancing its brand influence.
NASDAQ.COM
9.0
05-27NASDAQ.COM
FDA Approves LINZESS for Pediatric Constipation Treatment
  • FDA Approval: Ironwood Pharmaceuticals announced that LINZESS (linaclotide) has received FDA approval for the treatment of functional constipation in pediatric patients aged 2 years and older, making it the only FDA-approved prescription therapy for this chronic condition.
  • Clinical Trial Evidence: The approval is supported by data from a 12-week Phase 3 randomized, placebo-controlled clinical trial, which demonstrated a significant improvement in spontaneous bowel movement frequency compared to placebo, confirming its efficacy and safety.
  • Market Reaction: Following the announcement, Ironwood's stock rose by 2.18% on Nasdaq, currently trading at $3.98, indicating a positive market response to the drug's approval.
  • Strategic Implications: The approval of LINZESS not only provides a new treatment option for pediatric patients but also positions Ironwood for further expansion in the pediatric pharmaceutical market, enhancing its competitiveness in the gastrointestinal drug sector.
Newsfilter
8.5
05-27Newsfilter
FDA Approves LINZESS for Pediatric Functional Constipation in Ages 2-5
  • Indication Expansion: LINZESS (linaclotide) has received FDA approval for use in pediatric patients aged 2 years and older with functional constipation (FC), marking an expansion from the previous approval for ages 6 and older, and establishing it as the only FDA-approved prescription therapy in this category, addressing a significant treatment gap.
  • Clinical Trial Support: The FDA's approval was supported by a 12-week Phase 3 randomized, placebo-controlled trial demonstrating that LINZESS 72 mcg significantly improved spontaneous bowel movement frequency compared to placebo, further confirming its safety and efficacy in younger patients.
  • Market Leadership: Since its launch in 2012, LINZESS has been prescribed to over 5.5 million patients, maintaining its leadership position in the IBS-C (ages 7 and older) and adult chronic idiopathic constipation (CIC) markets, with this approval expected to further enhance its market share.
  • Ease of Administration: The contents of the LINZESS capsule can be mixed with applesauce or water, providing a flexible administration option that helps parents manage their children's medication more effectively, thereby improving adherence and treatment outcomes.
seekingalpha
9.5
05-26seekingalpha
Healthcare ETF Underperforms Amid Earnings Season
  • Healthcare ETF Performance: The Health Care Select Sector SPDR Fund ETF (XLV), which holds a significant 12.12% weight in the S&P 500, has declined 3.17% year-to-date, significantly underperforming the S&P 500's 9.17% gain, indicating weakness in the sector amid the current market environment.
  • Quant Rating System: Seeking Alpha's quant system rates small-cap healthcare stocks on a scale from 1 to 5, where scores above 3.5 are bullish and below 2.5 are bearish, providing investors with insights into potential opportunities within the lagging sector.
  • Top-Rated Stocks: Ironwood Pharmaceuticals (IRWD) received a quant rating of 4.93, classified as a Strong Buy, while Anteris Technologies Global (AVR) and Adlai Nortye (ANL) followed closely with ratings of 4.92 and 4.89, respectively, highlighting their strong performance post-earnings.
  • Bottom-Rated Stocks: Verastem (VSTM), Ascentage Pharma Group (AAPG), GeneDx Holdings (WGS), Organogenesis Holdings (ORGO), and Alvotech (ALVO) all received quant ratings between 1.06 and 1.07, categorized as Strong Sell, reflecting their weak positions in the market.
Wall Street analysts forecast IRWD stock price to rise
3 Analyst Rating
Wall Street analysts forecast IRWD stock price to rise
2 Buy
1 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
5.00
Averages
6.23
High
8.00
Current: 0.000
sliders
Low
5.00
Averages
6.23
High
8.00
Citizens
Jason Butler
Outperform
maintain
$8 -> $10
AI Analysis
2026-02-26
Reason
Citizens
Jason Butler
Price Target
$8 -> $10
AI Analysis
2026-02-26
maintain
Outperform
Reason
Citizens analyst Jason Butler raised the firm's price target on Ironwood to $10 from $8 and keeps an Outperform rating on the shares. Ironwood reported Q4 financial results consistent with prior guidance and more importantly reiterated 2026 guidance including adjusted EBITDA of more than $300M, the analyst tells investors in a research note. The firm continues to believe that 2026 guidance supports LINZESS headwinds have passed, and the asset can drive substantial cash flow between now and the loss of brand exclusivity to fund current debt obligations and the apraglutide confirmatory trial/commercial launch.
Craig-Hallum
Hold
to
Buy
upgrade
2026-01-05
Reason
Craig-Hallum
Price Target
2026-01-05
upgrade
Hold
to
Buy
Reason
Craig-Hallum upgraded Ironwood to Buy from Hold with a price target of $5.70, up from $3.80.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for IRWD
Unlock Now

Valuation Metrics

The current forward P/E ratio for Ironwood Pharmaceuticals Inc (IRWD.O) is 12.33, compared to its 5-year average forward P/E of 14.61. For a more detailed relative valuation and DCF analysis to assess Ironwood Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
14.61
Current PE
12.33
Overvalued PE
35.72
Undervalued PE
-6.51

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average EV/EBITDA
9.80
Current EV/EBITDA
3.01
Overvalued EV/EBITDA
16.36
Undervalued EV/EBITDA
3.24

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
3.04
Current PS
1.28
Overvalued PS
4.60
Undervalued PS
1.48

Financials

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Whales Holding IRWD

A
Armistice Capital LLC
Holding
IRWD
+6.75%
3M Return

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Frequently Asked Questions

What is Ironwood Pharmaceuticals Inc (IRWD) stock price today?

The current price of IRWD is 3.57 USD — it has decreased -0.83

What is Ironwood Pharmaceuticals Inc (IRWD)'s business?

Ironwood Pharmaceuticals, Inc. is a biotechnology company developing and commercializing life-changing therapies for people living with gastrointestinal (GI), and rare diseases. It is focused on the development and commercialization of GI product opportunities in areas of significant unmet need. LINZESS (linaclotide), its commercial product, is indicated for adult men and women suffering from irritable bowel syndrome with constipation (IBS-C), or chronic idiopathic constipation (CIC), and for pediatric patients ages 6-17 years-old suffering from functional constipation (FC). Linaclotide is available under the trademarked name CONSTELLA to adult men and women suffering from IBS-C or CIC and pediatric patients. The Company is also engaged in advancing apraglutide, a synthetic long-acting peptide analog of glucagon-like peptide-2 (GLP-2), for short bowel syndrome (SBS), patients who are dependent on parenteral support.

What is the price predicton of IRWD Stock?

Wall Street analysts forecast IRWD stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for IRWD is6.23 USD with a low forecast of 5.00 USD and a high forecast of 8.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Ironwood Pharmaceuticals Inc (IRWD)'s revenue for the last quarter?

Ironwood Pharmaceuticals Inc revenue for the last quarter amounts to 106.51M USD, increased 158.87

What is Ironwood Pharmaceuticals Inc (IRWD)'s earnings per share (EPS) for the last quarter?

Ironwood Pharmaceuticals Inc. EPS for the last quarter amounts to 0.24 USD, decreased -204.35

How many employees does Ironwood Pharmaceuticals Inc (IRWD). have?

Ironwood Pharmaceuticals Inc (IRWD) has 100 emplpoyees as of May 31 2026.

What is Ironwood Pharmaceuticals Inc (IRWD) market cap?

Today IRWD has the market capitalization of 587.67M USD.