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LPCN Overview

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$
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0.000(0.000%)Aft-market
ET
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0.000
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0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
2.600
Open
2.510
VWAP
2.46
Vol
736.05K
Mkt Cap
17.74M
Low
2.360
Amount
1.81M
EV/EBITDA(TTM)
--
Total Shares
7.30M
EV
3.76M
EV/OCF(TTM)
--
P/S(TTM)
7.06
Lipocine Inc. is a biopharmaceutical company leveraging its proprietary technology platform to enable effective oral delivery of therapeutics. The Company’s clinical development candidates include: LPCN 1154, oral brexanolone, for the treatment of postpartum depression, LPCN 2101, for the treatment of epilepsy, LPCN 2203, an oral candidate targeted for the management of essential tremor, LPCN 2401, an oral proprietary anabolic androgen receptor agonist for improved body composition in obesity management, and LPCN 1148, for the management of decompensated cirrhosis. It is also developing LPCN 1107, for the prevention of preterm birth, LPCN 1154, for rapid relief of postpartum depression, and LPCN 1144, for the treatment of metabolic dysfunction-associated steatohepatitis. Its product candidate, TLANDO, is a novel oral prodrug of testosterone containing testosterone undecanoate developed by the Company.
Show More

Events Timeline

(ET)
2026-04-02
08:10:00
Lipocine Announces Phase 3 Trial Results for LPCN 1154
select
2026-02-18 (ET)
2026-02-18
08:10:00
Lipocine Completes Final Patient Visit in Phase 3 Trial of LPCN 1154
select
2026-01-20 (ET)
2026-01-20
08:10:00
Lipocine Completes Enrollment for LPCN 1154 Phase 3 Trial
select
2026-01-12 (ET)
2026-01-12
08:20:00
Lipocine Completes Safety Review of LPCN 1154 Clinical Trial
select
2025-12-16 (ET)
2025-12-16
08:10:00
Lipocine Achieves 80% Enrollment Completion in LPCN 1154 Trial
select
2025-11-18 (ET)
2025-11-18
09:36:50
Lipocine announces 'encouraging' safety results in Phase 3 trial of LPCN 1154
select

News

stocktwits
2.0
04-02stocktwits
Lipocine's Experimental Drug Trial Fails to Meet Primary Endpoint
  • Trial Outcome: Lipocine's experimental drug LPCN 1154 failed to significantly reduce postpartum depression severity in trials, resulting in a 78% drop in stock price on Thursday, reflecting market concerns about the company's future prospects.
  • Favorable Safety Profile: Despite not meeting the primary endpoint, the drug was well tolerated and demonstrated a favorable safety profile, supporting outpatient use without healthcare provider monitoring, indicating potential applications in specific patient populations.
  • Potential Development Signals: The company identified signals in a post hoc analysis that could indicate a potential development path for LPCN 1154 and has applied for breakthrough therapy and fast track designations, highlighting its focus on future market opportunities.
  • Shareholder Engagement Plans: Lipocine plans to preserve capital and engage with shareholders to evaluate all available options, including continued development of LPCN 1154, demonstrating the company's determination to seek strategic transformation in adversity.
NASDAQ.COM
9.5
04-02NASDAQ.COM
Lipocine Inc. Shares Plunge 78% After Phase 3 Trial Failure
  • Trial Failure Announcement: Lipocine Inc. reported that its Phase 3 trial for LPCN 1154, aimed at treating postpartum depression, failed to meet its primary endpoint, resulting in a staggering 78% drop in share price during Thursday morning trading, from $9.25 to $2.00, indicating strong market disappointment in the product's prospects.
  • Stock Price Fluctuation: The company's stock has traded between $2.01 and $12.37 over the past year, with the current price reflecting extreme pessimism among investors regarding its future, potentially impacting its ability to raise capital and maintain market confidence.
  • Capital Preservation Strategy: Lipocine announced plans to preserve capital and engage with stakeholders, including investors, regulators, and advisors, to evaluate all available options moving forward, aiming to stabilize operations and seek potential turnaround opportunities.
  • Market Reaction Analysis: The significant drop in stock price not only affects the company's market capitalization but may also lead to diminished investor confidence in its future R&D projects, posing challenges to its long-term growth trajectory.
PRnewswire
9.0
04-02PRnewswire
Lipocine Reports Phase 3 Trial Results for LPCN 1154 in Postpartum Depression
  • Clinical Trial Results: Lipocine Inc. announced that LPCN 1154 did not achieve statistically significant reductions in HAM-D scores compared to placebo at 60 hours, indicating that the drug failed to meet its primary endpoint, which may adversely affect its market prospects.
  • Safety Profile: Despite not meeting the primary efficacy endpoint, LPCN 1154 demonstrated good tolerability and a favorable safety profile, with no severe adverse events reported, supporting its potential for outpatient use and future clinical applications.
  • Future Development Plans: The company conducted a post hoc analysis for participants with a history of psychiatric conditions and has applied for breakthrough therapy and fast track designations for LPCN 1154, reflecting a proactive stance on the drug's future development despite uncertainties regarding FDA feedback.
  • Market Demand Context: Postpartum depression affects approximately 20-40% of new mothers, and traditional antidepressants have slow onset and significant side effects; LPCN 1154's rapid relief characteristics could address this unmet market need, positioning it as a potential first-line treatment.
seekingalpha
9.5
03-10seekingalpha
Lipocine Reports FY GAAP EPS of -$1.69
  • Financial Overview: Lipocine's FY report reveals a GAAP EPS of -$1.69, indicating significant challenges in profitability that could undermine investor confidence moving forward.
  • Revenue Performance: The company reported total revenue of $1.97 million, which, while providing some income, falls short of industry expectations, raising concerns about its future growth potential in a competitive market.
  • Historical Data Comparison: Historical financial data for Lipocine suggests that despite ongoing investments in R&D, revenue growth has not met projections, indicating a need to reassess its business model for sustainable development.
  • Market Reaction Expectations: Given the reported losses and low revenue, the market may react negatively to Lipocine's stock price, prompting investors to closely monitor subsequent strategic adjustments and financial improvement measures.
PRnewswire
9.0
02-18PRnewswire
Lipocine Completes Phase 3 Trial for LPCN 1154 in Postpartum Depression
  • Trial Completion: Lipocine announced the completion of the last patient visit in its Phase 3 trial for LPCN 1154 (oral brexanolone), enrolling 90 patients with severe postpartum depression and an average baseline Hamilton depression rating scale of 28.3, demonstrating a positive safety and tolerability profile.
  • Safety Profile: All reported nervous system adverse events were mild to moderate, with no instances of drug discontinuation or serious adverse events, establishing a solid foundation for LPCN 1154 as a patient-centric treatment option.
  • Rapid Relief Potential: Designed to provide rapid symptom relief for postpartum depression with a treatment duration of only 48 hours and no need for medical monitoring, LPCN 1154 is expected to encourage healthcare professionals to prescribe it, addressing urgent patient needs for quick improvement.
  • Future Prospects: Data from this trial is anticipated to support a 505(b)(2) NDA submission in 2026, and if efficacy results are positive, it could significantly enhance LPCN 1154's role in postpartum depression treatment, addressing gaps in existing therapies.
Globenewswire
7.5
01-19Globenewswire
Doseology Sciences Partners with McKinney to Enhance Regulatory Compliance Strategy
  • Market Growth: The consumer healthcare market is projected to reach $362 billion in 2026, prompting companies to prioritize regulatory certainty as a key component of their business strategies in a competitive landscape.
  • Increased M&A Activity: A 12% rise in merger activity is anticipated in 2026 as companies pursue acquisitions to enhance technological efficiency, underscoring the critical need for thorough due diligence in navigating federal risks.
  • Strategic Partnership: Doseology has partnered with McKinney Regulatory Science Advisors to expedite product development and market access through expert FDA compliance consulting, ensuring alignment with regulatory expectations.
  • Market Outlook: Doseology aims to enter a global pouch market expected to exceed $69.46 billion by 2032, advancing towards commercialization with a clear regulatory strategy and secured manufacturing infrastructure.
Wall Street analysts forecast LPCN stock price to rise
2 Analyst Rating
Wall Street analysts forecast LPCN stock price to rise
2 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
6.75
Averages
6.88
High
7.00
Current: 0.000
sliders
Low
6.75
Averages
6.88
High
7.00
Alliance Global
Buy
downgrade
$11 -> $6
AI Analysis
2026-04-13
Reason
Alliance Global
Price Target
$11 -> $6
AI Analysis
2026-04-13
downgrade
Buy
Reason
Alliance Global lowered the firm's price target on Lipocine to $6 from $11 and keeps a Buy rating on the shares, noting that the company announced on April 2 that oral brexanolone for the treatment of postpartum depression did not show a statistically significant reduction from baseline in depression scale when compared to placebo at 60 hours, missing the study's primary endpoint. The firm's initial analysis "suggests that this event may be more of a case of a failed trial than a failed compound" and it believes that the company may have a path forward to "redo this trial in a reasonable time period," the analyst tells investors.
H.C. Wainwright
Buy
to
Neutral
downgrade
$NULL
2026-04-06
Reason
H.C. Wainwright
Price Target
$NULL
2026-04-06
downgrade
Buy
to
Neutral
Reason
H.C. Wainwright downgraded Lipocine to Neutral from Buy without a price target after LPCN 1154 did not meet the efficacy endpoint in the Phase 3 trial. The firm cites uncertainty of Lipocine's development going forward for the downgrade.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for LPCN
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Valuation Metrics

The current forward P/E ratio for Lipocine Inc (LPCN.O) is 5.64, compared to its 5-year average forward P/E of -4.28. For a more detailed relative valuation and DCF analysis to assess Lipocine Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.28
Current PE
5.64
Overvalued PE
-1.39
Undervalued PE
-7.18

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.45
Current EV/EBITDA
-5.78
Overvalued EV/EBITDA
1.63
Undervalued EV/EBITDA
-2.54

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
18.49
Current PS
17.14
Overvalued PS
38.12
Undervalued PS
-1.15

Financials

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Frequently Asked Questions

What is Lipocine Inc (LPCN) stock price today?

The current price of LPCN is 2.43 USD — it has decreased -5.08

What is Lipocine Inc (LPCN)'s business?

Lipocine Inc. is a biopharmaceutical company leveraging its proprietary technology platform to enable effective oral delivery of therapeutics. The Company’s clinical development candidates include: LPCN 1154, oral brexanolone, for the treatment of postpartum depression, LPCN 2101, for the treatment of epilepsy, LPCN 2203, an oral candidate targeted for the management of essential tremor, LPCN 2401, an oral proprietary anabolic androgen receptor agonist for improved body composition in obesity management, and LPCN 1148, for the management of decompensated cirrhosis. It is also developing LPCN 1107, for the prevention of preterm birth, LPCN 1154, for rapid relief of postpartum depression, and LPCN 1144, for the treatment of metabolic dysfunction-associated steatohepatitis. Its product candidate, TLANDO, is a novel oral prodrug of testosterone containing testosterone undecanoate developed by the Company.

What is the price predicton of LPCN Stock?

Wall Street analysts forecast LPCN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for LPCN is6.88 USD with a low forecast of 6.75 USD and a high forecast of 7.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Lipocine Inc (LPCN)'s revenue for the last quarter?

Lipocine Inc revenue for the last quarter amounts to 1.15M USD, decreased -67.19

What is Lipocine Inc (LPCN)'s earnings per share (EPS) for the last quarter?

Lipocine Inc. EPS for the last quarter amounts to -0.42 USD, decreased -235.48

How many employees does Lipocine Inc (LPCN). have?

Lipocine Inc (LPCN) has 14 emplpoyees as of April 20 2026.

What is Lipocine Inc (LPCN) market cap?

Today LPCN has the market capitalization of 17.74M USD.