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CAI Overview

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0.000(0.000%)Aft-market
ET
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0.000
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ET
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Intellectia

Loading chart...

High
21.000
Open
20.380
VWAP
20.72
Vol
1.88M
Mkt Cap
5.92B
Low
20.200
Amount
38.97M
EV/EBITDA(TTM)
78.04
Total Shares
282.58M
EV
5.29B
EV/OCF(TTM)
63.56
P/S(TTM)
7.08
Caris Life Sciences Inc. is a patient-centric, next-generation artificial intelligence tech bio company and precision medicine provider. The Company develops and commercializes solutions to transform healthcare through the use of comprehensive molecular information and artificial intelligence/machine learning algorithms at scale. Its entire portfolio of precision medicine solutions is designed to benefit patients, with an initial focus on oncology, and serves the clinical, academic, and biopharma markets. Its platform is purpose-built to leverage the convergence of next-generation sequencing (NGS), artificial intelligence (AI) and machine learning (ML) technologies, and high-performance computing. Its purpose-built, proprietary multi-omic profiling solutions capture and analyze molecular information from tissue and blood in a comprehensive manner. Its services for biopharma companies include prospective and retrospective profiling services, and companion diagnostics development.
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Events Timeline

(ET)
2026-04-02
08:40:00
Caris Life Sciences Launches Caris ChromoSeq Whole Genome Sequencing
select
2026-03-20 (ET)
2026-03-20
08:40:00
Caris Study Shows AI Improves Lung Cancer Diagnosis
select
2026-03-16 (ET)
2026-03-16
08:40:00
Caris Life Sciences Launches Platinum Resistance AI Signature
select

News

PRnewswire
8.5
04-15PRnewswire
PinnedCaris Life Sciences Advances Access to Cancer Clinical Trials Nationwide
  • Access Gap in Trials: Research indicates that 70% of U.S. counties lack active cancer treatment trials, leaving nearly one in five Americans aged 55 and older without local access to investigational therapies; Caris's RIT solution aims to bridge this gap by deploying trials directly to community oncology practices.
  • Increased Patient Participation: A meta-analysis in the Journal of the National Cancer Institute found that 55% of cancer patients offered a trial agree to participate, suggesting that access and infrastructure, rather than patient willingness, are the main barriers, which Caris addresses through rapid molecular profiling and trial matching.
  • Integrated Technology Advantage: The Caris RIT solution integrates comprehensive molecular profiling, automated trial matching, and streamlined site activation, ensuring that patients can transition from molecular analysis to trial enrollment in approximately two weeks, significantly enhancing treatment accessibility.
  • Data-Driven Decision Making: As of December 31, 2025, Caris has established over 1.016 million molecular tumor profiles and 740,000 matched profiles, supporting clinical decision-making and driving the standardization of precision medicine, ensuring every cancer patient receives a treatment plan informed by their molecular profile.
Newsfilter
7.5
04-15Newsfilter
Caris Life Sciences Advances Access to Cancer Clinical Trials Nationwide
  • Clinical Trial Access Gap: Research indicates that 70% of U.S. counties lack active cancer treatment trials, leaving nearly one in five Americans aged 55 and older without local access to investigational therapies; Caris's RIT solution aims to bridge this gap by deploying trials directly to community oncology practices.
  • Increased Patient Participation: Among cancer patients offered trials, 55% agree to participate, suggesting that the main barriers are access and infrastructure rather than patient willingness; Caris's rapid molecular profiling and trial matching are expected to significantly enhance patient enrollment rates.
  • Rapid Trial Matching: The RIT solution can move from molecular profiling to patient enrollment in approximately two weeks, and as quickly as five days, ensuring patients receive care locally while minimizing the burden of long-distance travel, thereby improving their treatment experience.
  • Extensive Database Support: As of December 31, 2025, Caris has established over 1.016 million molecular tumor profiles and 740,000 matched profiles, facilitating precise trial matching and advancing the adoption of precision medicine to ensure every cancer patient receives treatment informed by their molecular profile.
PRnewswire
5.0
04-08PRnewswire
Caris Launches AI-Driven NSCLC Treatment Selection Signature
  • AI-Driven Treatment Selection: Caris Life Sciences has launched an AI-driven molecular insight for non-small cell lung cancer (NSCLC) patients eligible for mono-immunotherapy, aiming to enhance survival rates by integrating whole exome and transcriptome sequencing data to guide physicians in chemotherapy decisions.
  • Advancement in Precision Medicine: The newly developed NSCLC immunotherapy selection signature utilizes machine learning to identify complex molecular signatures, stratifying patients into high-risk and standard-risk groups, thereby predicting which patients may benefit from chemotherapy and reducing unnecessary exposure, significantly improving patient treatment experiences.
  • Innovation in Clinical Application: The introduction of this signature not only provides physicians with a unique molecular signature for more scientifically informed treatment decisions but also underscores the importance of personalized treatment strategies, marking Caris's ongoing innovation in the field of precision oncology.
  • FDA Approval Context: Caris received FDA approval for MI Cancer Seek in November 2024, becoming the first assay to simultaneously utilize whole exome and transcriptome sequencing as a companion diagnostic tool, further solidifying its leadership position in molecular oncology.
Newsfilter
5.0
04-08Newsfilter
Caris Launches AI-Driven Molecular Insights for Lung Cancer Treatment
  • Breakthrough in Precision Treatment: Caris Life Sciences has launched AI-driven molecular insights for non-small cell lung cancer (NSCLC) patients, aiming to enhance survival rates by integrating whole exome and transcriptome sequencing data to assist physicians in making more precise immunotherapy and chemotherapy combination choices.
  • Clinical Decision Support: The newly developed treatment selection signature identifies which patients may benefit from chemotherapy and which may be harmed, significantly reducing unnecessary chemotherapy exposure and improving patient treatment experiences and quality of life.
  • Data-Driven Personalized Medicine: This signature leverages Caris's large-scale clinico-genomic datasets and employs machine learning to identify complex molecular signatures, moving beyond traditional small panel biomarker tests to provide more biologically guided treatment options.
  • Enhanced Industry Impact: Caris's innovation not only offers new treatment options for NSCLC patients but also further solidifies its leadership position in the precision medicine field, demonstrating its commitment to transforming healthcare.
PRnewswire
5.0
04-02PRnewswire
Caris Launches Advanced Whole Genome Sequencing Technology
  • Technological Innovation: Caris Life Sciences has launched Caris ChromoSeq™, a Whole Genome and Whole Transcriptome Sequencing assay designed to provide comprehensive clinical genomic evaluations for myeloid malignancies, which is expected to significantly enhance diagnostic efficiency.
  • Enhanced Data Depth: The assay delivers approximately 250x read depth across the genome and 40 million transcriptome reads, enabling higher genomic resolution from bone marrow aspirates or peripheral blood samples, thereby accelerating the clinical decision-making process.
  • Simplified Reporting: Caris ChromoSeq integrates multiple test results into a single, easy-to-interpret report, with an expected turnaround time of seven days, helping physicians make rapid treatment decisions and reducing patient wait times.
  • Market Outlook: The launch of this technology underscores Caris's ongoing commitment to precision medicine, aiming to support clinicians by simplifying complexity and advancing the diagnosis and treatment of hematological cancers.
Newsfilter
3.5
04-02Newsfilter
Caris Launches Advanced Whole Genome and Transcriptome Sequencing Technology
  • Technological Innovation: Caris Life Sciences has launched Caris ChromoSeq™, a Whole Genome Sequencing and Whole Transcriptome Sequencing assay designed to provide comprehensive clinical genomic evaluations for myeloid malignancies, which is expected to significantly enhance diagnostic efficiency.
  • Enhanced Data Depth: The test delivers approximately 250x read depth across the genome and 40 million transcriptome reads, enabling higher genomic resolution from bone marrow or peripheral blood samples, thereby accelerating clinical decision-making.
  • Streamlined Diagnostic Process: Caris ChromoSeq can replace traditional multiple testing protocols, consolidating results into a single, easy-to-interpret report with an expected turnaround time of seven days, assisting physicians in making rapid treatment decisions that improve patient outcomes.
  • Strategic Implications: This technology launch underscores Caris's ongoing commitment to precision medicine, aiming to simplify complexity through innovative molecular profiling technologies that support clinicians in their decision-making processes across the cancer care continuum.
Wall Street analysts forecast CAI stock price to rise
7 Analyst Rating
Wall Street analysts forecast CAI stock price to rise
6 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
30.00
Averages
36.17
High
40.00
Current: 0.000
sliders
Low
30.00
Averages
36.17
High
40.00
Jefferies
Tycho Peterson
Buy
initiated
$28
AI Analysis
2026-04-12
New
Reason
Jefferies
Tycho Peterson
Price Target
$28
AI Analysis
2026-04-12
New
initiated
Buy
Reason
Jefferies analyst Tycho Peterson initiated coverage of Caris Life Sciences with a Buy rating and $28 price target. The firm sees \"secular tailwinds\" in the oncology diagnostics space from improving therapies and declining sequencing costs, but also \"ongoing polarization between the leaders and laggards.\" Jefferies views Caris Life Sciences and Veracyte as \"compelling stocks\" given their profitability, pipelines and valuations.
Piper Sandler
Neutral
initiated
$21
2026-04-10
Reason
Piper Sandler
Price Target
$21
2026-04-10
initiated
Neutral
Reason
Piper Sandler initiated coverage of Caris Life Sciences with a Neutral rating and $21 price target. The firm says the company has built a \"rare combination\" of scientific leadership and financial sustainability in a sector where most competitors remain unprofitable. Piper believes Caris can grow total revenue near 20% over the next couple of years, but looks for therapy selection growth acceleration through salesforce expansion or new products before recommending the shares.
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Valuation Metrics

The current forward P/E ratio for Caris Life Sciences Inc (CAI.O) is 38.02, compared to its 5-year average forward P/E of 190.84. For a more detailed relative valuation and DCF analysis to assess Caris Life Sciences Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
190.84
Current PE
38.02
Overvalued PE
560.15
Undervalued PE
-178.47

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
15645.61
Current EV/EBITDA
13.11
Overvalued EV/EBITDA
40363.59
Undervalued EV/EBITDA
-9072.37

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
7.72
Current PS
4.64
Overvalued PS
10.91
Undervalued PS
4.52

Financials

AI Analysis
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Whales Holding CAI

P
Perceptive Advisors LLC
Holding
CAI
+16.96%
3M Return
B
Braidwell LP
Holding
CAI
+12.09%
3M Return
C
Coatue Management
Holding
CAI
+7.17%
3M Return
G
Ghisallo Capital Management LLC
Holding
CAI
+6.67%
3M Return
P
PointState Capital LP
Holding
CAI
+3.02%
3M Return
R
Rock Springs Capital Management LP
Holding
CAI
+2.91%
3M Return

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Frequently Asked Questions

What is Caris Life Sciences Inc (CAI) stock price today?

The current price of CAI is 20.95 USD — it has increased 3.76

What is Caris Life Sciences Inc (CAI)'s business?

Caris Life Sciences Inc. is a patient-centric, next-generation artificial intelligence tech bio company and precision medicine provider. The Company develops and commercializes solutions to transform healthcare through the use of comprehensive molecular information and artificial intelligence/machine learning algorithms at scale. Its entire portfolio of precision medicine solutions is designed to benefit patients, with an initial focus on oncology, and serves the clinical, academic, and biopharma markets. Its platform is purpose-built to leverage the convergence of next-generation sequencing (NGS), artificial intelligence (AI) and machine learning (ML) technologies, and high-performance computing. Its purpose-built, proprietary multi-omic profiling solutions capture and analyze molecular information from tissue and blood in a comprehensive manner. Its services for biopharma companies include prospective and retrospective profiling services, and companion diagnostics development.

What is the price predicton of CAI Stock?

Wall Street analysts forecast CAI stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CAI is36.17 USD with a low forecast of 30.00 USD and a high forecast of 40.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Caris Life Sciences Inc (CAI)'s revenue for the last quarter?

Caris Life Sciences Inc revenue for the last quarter amounts to 292.89M USD, increased 125.44

What is Caris Life Sciences Inc (CAI)'s earnings per share (EPS) for the last quarter?

Caris Life Sciences Inc. EPS for the last quarter amounts to 0.29 USD, decreased -231.82

How many employees does Caris Life Sciences Inc (CAI). have?

Caris Life Sciences Inc (CAI) has 1846 emplpoyees as of April 16 2026.

What is Caris Life Sciences Inc (CAI) market cap?

Today CAI has the market capitalization of 5.92B USD.