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ALKS Should I Buy

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Intellectia

Should You Buy Alkermes Plc (ALKS) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
35.360
1 Day change
17.28%
52 Week Range
36.320
Analysis Updated At
2026/03/26
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Alkermes Plc (ALKS) is not a strong buy for a beginner investor with a long-term strategy at this time. The lack of significant positive catalysts, declining financial performance, and neutral trading sentiment suggest holding off on investment until clearer growth trends or stronger signals emerge.

Technical Analysis

The MACD is positive and expanding, indicating bullish momentum. RSI is in the neutral zone at 72.167, showing no overbought or oversold conditions. Moving averages are converging, suggesting a lack of a strong trend. The stock is trading near its resistance level (R1: 29.686), which may limit immediate upside potential.

Options Data

Bearish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
5
Buy
13

Positive Catalysts

  • Analysts maintain optimistic long-term views on the company's narcolepsy franchise, with Lumryz and alixorexant as key growth drivers. Gross margin increased YoY, reflecting operational efficiency.

Neutral/Negative Catalysts

  • Revenue, net income, and EPS have all declined significantly YoY in the latest quarter (2025/Q4). No recent news or significant insider or hedge fund activity. Congress trading data is absent. The stock has a 70% chance of declining slightly in the short term.

Financial Performance

In 2025/Q4, revenue dropped by -10.57% YoY to $384.55M. Net income fell by -66.32% YoY to $49.34M, and EPS declined by -67.05% YoY to $0.29. However, gross margin improved by 2.84% YoY to 87.98%.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts have mixed ratings. Piper Sandler and Wolfe Research are optimistic, with price targets of $43-$45 and Overweight/Outperform ratings. H.C. Wainwright and BofA are more cautious, with Neutral ratings and lower price targets of $34-$43. Analysts highlight the company's emerging narcolepsy franchise as a key growth area but note challenges with legacy products.

Wall Street analysts forecast ALKS stock price to rise
12 Analyst Rating
Wall Street analysts forecast ALKS stock price to rise
10 Buy
2 Hold
0 Sell
Strong Buy
Current: 30.150
sliders
Low
37
Averages
46.2
High
58
Current: 30.150
sliders
Low
37
Averages
46.2
High
58
Piper Sandler
David Amsellem
Overweight
downgrade
$45 -> $43
AI Analysis
2026-03-24
Reason
Piper Sandler
David Amsellem
Price Target
$45 -> $43
AI Analysis
2026-03-24
downgrade
Overweight
Reason
Piper Sandler analyst David Amsellem lowered the firm's price target on Alkermes (ALKS) to $43 from $45 and keeps an Overweight rating on the shares. Looking further into 2026, the firm believes Lumryz should be every bit as consequential to Alkermes shares as is orexin 2 receptor agonist alixorexton. There is of course the expected Q2 read-out of the Phase III REVITALYZ study evaluating Lumryz in idiopathic hypersomnia, and then early metrics on Takeda's (TAK) oveporexton in narcolepsy type 1. On this latter point, Piper does not envision much pressure on oxybate products.
H.C. Wainwright
Neutral
downgrade
$46 -> $43
2026-02-26
Reason
H.C. Wainwright
Price Target
$46 -> $43
2026-02-26
downgrade
Neutral
Reason
H.C. Wainwright lowered the firm's price target on Alkermes to $43 from $46 and keeps a Neutral rating on the shares. The company's 2026 revenue guidance reflects expected consistent growth of its psychiatry portfolio, the analyst tells investors in a research note. The firm says that while Alkermes' legacy products may have some incremental growth, the investment story is shifting to the company's sleep franchise, which is anchored commercially by Lumryz for the time being as alixorexant enters late-stage development.
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