Zentalis Pharmaceuticals to Showcase Four Azenosertib Posters at AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Oct 13 2025
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Source: Newsfilter
Zentalis Pharmaceuticals Announcement: Zentalis Pharmaceuticals has announced that four abstracts related to their WEE1 inhibitor, azenosertib, have been accepted for presentation at the AACR-NCI-EORTC International Conference, highlighting its potential in treating Cyclin E1-positive platinum-resistant ovarian cancer.
Clinical Trial Insights: The presentations will cover Phase 1 results and ongoing studies, emphasizing azenosertib's role as a monotherapy and in combination therapies, with a focus on its biomarker-driven strategy for underserved patient populations.
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Analyst Views on ZNTL
Wall Street analysts forecast ZNTL stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ZNTL is 6.60 USD with a low forecast of 4.00 USD and a high forecast of 10.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
6 Analyst Rating
4 Buy
2 Hold
0 Sell
Moderate Buy
Current: 2.560
Low
4.00
Averages
6.60
High
10.00
Current: 2.560
Low
4.00
Averages
6.60
High
10.00
About ZNTL
Zentalis Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on discovering and developing small molecule therapeutics targeting fundamental biological pathways of cancers. The Company is engaged in developing azenosertib (ZN-c3), a potentially first-in-class WEE1 inhibitor, for patients with ovarian cancer and other tumor types. The inhibition of WEE1, a DNA damage response kinase, drives cancer cells into mitosis without being able to repair damaged DNA, resulting in cell death and thereby preventing tumor growth and potentially causing tumor regression. WEE1 acts as a regulator of the G1-S and G2-M cell cycle checkpoints, through negative regulation of both CDK1 and CDK2, to prevent replication of cells with damaged DNA. In clinical trials, azenosertib has been well tolerated and has demonstrated anti-tumor activity as a single agent across multiple tumor types.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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