Syndax Updates 2026 Business Priorities and Milestones
Syndax provided additional business updates ahead of its presentation at the 44th Annual J.P. Morgan Healthcare conference. Key 2026 Priorities & Anticipated Milestones: Drive Revuforj and Niktimvo net revenue growth; Complete enrollment in MAXPIRe Phase 2 trial of axatilimab in idiopathic pulmonary fibrosis; Advance global enrollment in EVOLVE-2 and REVEAL-ND; Initiate RAVEN, a Phase 2 collaborative trial of revumenib in combination with venetoclax and azacitidine in newly diagnosed KMT2Ar patients who would be considered eligible, or fit, for intensive chemotherapy in 2026; Further leadership in menin and CSF-1R inhibition through the publication and presentation of clinical trial data; Initiate a program in 2026 designed to generate proof-of-principle clinical data with revumenib in myelofibrosis
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Syndax Partners with WODA to Expand Access to Revuforj in Multiple Regions
- Global Access Program: Syndax collaborates with WODA to launch a Managed Access Program aimed at expanding access to Revuforj in regions like Eurasia, the Middle East, Latin America, and Africa, potentially benefiting thousands of patients.
- Physician Experience Accumulation: This program not only provides a pathway for patients to access Revuforj but also allows more physicians to gain firsthand experience with the drug, supporting the long-term goal of establishing Revuforj as a standard treatment globally.
- FDA Approval Context: Revuforj is FDA-approved in the U.S. for treating difficult-to-treat acute leukemia, highlighting its significance in blood cancer treatment and expected to enhance Syndax's competitiveness in the global market.
- Role of WODA: WODA will provide Revuforj in over 150 countries, ensuring compliant and patient-focused distribution, further strengthening Syndax's influence in the global drug access landscape.

Syndax Pharmaceuticals Inc. Offers 10.4% Annualized Return on $13 Put Options
- Options Selling Yield: Syndax Pharmaceuticals Inc.'s $13 put option offers a 10.4% annualized return, although the seller only acquires shares if the stock price falls by 39%, illustrating the complex relationship between risk and reward in options trading.
- Cost Basis Analysis: If the contract is exercised, the investor's cost basis would be $10.20 per share after accounting for the $2.80 premium, indicating that investors must carefully assess potential losses against current market price of $21.36.
- Volatility Consideration: With a trailing twelve-month volatility of 68% for Syndax, this provides investors a reference point for evaluating the risks of selling options, and combining this with fundamental analysis can help determine if the risk is worthwhile.
- Market Price Comparison: The current market price of $21.36 compared to the $13 strike price highlights the potential attractiveness of the options selling strategy, especially in a high volatility market, which may offer additional income opportunities for investors.









