Smith+Nephew Comparative Study Reveals PICO◊ sNPWT (-80 mmHg) Outperforms PrevenaTM -125 mmHg sNPWT in Reducing Wound Dehiscence and Healthcare Costs in Cardiovascular and Orthopedic Surgery
Study Findings: A comparative study by Smith+Nephew reveals that the PICO single-use negative pressure wound therapy (sNPWT) device significantly reduces wound dehiscence, hospital length of stay, and healthcare costs compared to the Prevena sNPWT device in orthopedic and cardiovascular surgeries.
Impact on Surgical Outcomes: The study, analyzing data from over 22,000 patients, shows a 57.8% reduction in wound dehiscence risk and a 9.1% reduction in hospital stay for cardiovascular surgeries, while orthopedic surgeries saw a 63.9% reduction in wound dehiscence and a 29.7% reduction in length of stay.
Economic Benefits: The use of PICO sNPWT resulted in substantial cost savings, with reductions in admission-related costs and expenditures within three months post-surgery, highlighting its potential to alleviate strain on healthcare resources.
Growing Evidence: These findings align with global recommendations for the prophylactic use of incisional negative pressure wound therapy (iNPWT) to minimize surgical site infections, reinforcing its importance in surgical practices for at-risk patients.
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Smith+Nephew Acquires Integrity Orthopaedics, Enhancing Shoulder Repair Technology
- Acquisition Integration: Smith+Nephew has completed the acquisition of US-based Integrity Orthopaedics, further strengthening its sports medicine shoulder repair business by offering the most comprehensive suite of rotator cuff repair technologies available, which is expected to significantly enhance market competitiveness.
- Innovative Technology: The Tendon Seam™ system from Integrity Orthopaedics features a unique repair stitch configuration and patented microanchors designed to reduce re-tear rates and improve patient outcomes, with early clinical data indicating lower re-tear rates and faster recovery compared to traditional methods.
- Market Potential: With approximately 500,000 rotator cuff repair procedures performed annually in the US, and traditional techniques suffering from structural failure rates of 20-40%, the introduction of Tendon Seam™ is poised to change this landscape, enhancing surgical success rates and patient satisfaction.
- Global Promotion Plan: Smith+Nephew plans to leverage its commercial channels in the US to accelerate the adoption of Tendon Seam™, while building a base of evidence to support global adoption, further solidifying its leadership position in the biomechanical repair sector.

Goldman Sachs Downgrades Super Micro Computer to Sell with $26 Price Target
- Rating Downgrade: Goldman Sachs analyst Katherine Murphy initiated coverage of Super Micro Computer (NASDAQ:SMCI) on January 13 with a Sell rating and a price target of $26, reflecting a pessimistic outlook that may lead to decreased investor confidence.
- Merger Approval: Shareholders of Huntington Bancshares (NASDAQ:HBAN) and Cadence Bank approved their pending merger on January 6, which is expected to enhance market competitiveness and resource integration, driving future business growth.
- Analyst Support: Multiple analysts initiated coverage of Medline Inc. (NASDAQ:MDLN) on January 12 with bullish ratings, indicating a positive market sentiment towards the company's prospects that could attract more investor interest.
- Market Reaction: Super Micro Computer's shares jumped 11.1% to settle at $32.66 on Friday, indicating mixed market reactions to Jim Cramer's sell recommendation, which may influence subsequent investment decisions.





