Significant ETF Withdrawals: UPRO, TMO, DIS, BKNG
52-Week Range of UPRO: UPRO's share price has a 52-week low of $45.88 and a high of $122.19, with the last trade recorded at $114.95.
Understanding ETFs: Exchange-traded funds (ETFs) function like stocks, where investors buy and sell "units" that can be created or destroyed based on demand.
Monitoring ETF Flows: Weekly monitoring of shares outstanding helps identify ETFs with significant inflows (new units created) or outflows (old units destroyed), impacting the underlying holdings.
Disclaimer: The views expressed in the article are those of the author and do not necessarily represent Nasdaq, Inc.
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- Share Acquisition Details: Kemnay Advisory Services Inc. increased its position in MercadoLibre by 1,385 shares during Q4 2026, with an estimated trade value of $2.91 million, bringing total holdings to 5,623 shares and reflecting a $1.42 million increase from the previous quarter due to both trading and stock price effects.
- Holding Proportion Analysis: Following this purchase, Kemnay's stake in MercadoLibre represents 1.71% of its 13F AUM, indicating a sustained bullish outlook on the company despite a 3.77% decline in share price over the past year.
- Market Performance Overview: As of February 16, 2026, MercadoLibre shares were priced at $1,988.26, with a market capitalization of $100.80 billion, maintaining rapid revenue growth despite pressures from increased e-commerce competition and rising bad loans.
- Investor Outlook: Kemnay has held MercadoLibre shares since Q2 2020, having previously sold off shares, but has now added shares in each of the last four quarters, suggesting they view the current stock price as an attractive buying opportunity, potentially leading to further purchases in the future.
- Share Increase: Kemnay Advisory Services Inc. disclosed a purchase of 1,385 shares of MercadoLibre in Q4 2026, with an estimated trade value of $2.91 million, indicating confidence in the company's prospects.
- Holding Status: As of February 2026, Kemnay's total holdings in MercadoLibre reached 5,623 shares, reflecting a $1.42 million increase from the previous quarter, showcasing a positive market sentiment.
- Market Performance: Despite MercadoLibre's share price declining by 3.77% over the past year and trailing the S&P 500 by 15.56 percentage points, Kemnay's increased stake suggests they view the current price as attractive.
- Investment Opportunity: Since acquiring shares in Q2 2020, Kemnay's recent purchases over the last four quarters may indicate confidence in the company's growth potential, particularly as economic conditions improve in Argentina and Venezuela.
- Investment Expansion: Novo Nordisk announced a €432 million ($506 million) investment in Ireland to expand production capacity for the Wegovy pill, aiming to meet future global demand, particularly outside the U.S. market.
- Competitive Pressure: This investment follows Novo losing market share to Eli Lilly, with analysts noting that despite competitive pressures, this move demonstrates the company's commitment to the oral medication market, potentially helping to restore market confidence.
- Supply Assurance: Novo has stated that it has resolved supply issues for Wegovy and has enough product to meet U.S. demand; however, challenges remain in meeting global demand, especially as it seeks to launch in other countries.
- Future Outlook: The construction projects in Ireland are set to be completed gradually between 2027 and 2028, expected to include technological upgrades of existing facilities, further enhancing Novo's competitiveness in the obesity drug market, particularly in its strategic focus on oral medications.

Agreement Announcement: AIM Immunotech has signed an agreement with the Thermo Fisher Scientific for the Phase 3 trial of its drug Ampligen.
Trial Focus: The Phase 3 trial will focus on evaluating the efficacy and safety of Ampligen in treating specific medical conditions.
- Settlement Reached: Novartis has reached a confidential settlement with the family of Henrietta Lacks, marking a resolution to the controversy surrounding the use of her cells without consent for medical research, with both parties expressing satisfaction despite undisclosed financial terms, indicating a recognition of historical injustices.
- Legal Context: The Lacks family filed the lawsuit nearly 70 years after her death, arguing that companies profited from cells obtained without permission, reflecting the complexities of ethics and legality in the biotech industry, particularly regarding patient consent.
- Scientific Contributions: Lacks' HeLa cells are renowned for their ability to multiply indefinitely in laboratory conditions, advancing global vaccine and disease research, with the World Health Organization crediting them for significant breakthroughs in polio, HIV, and cancer research, highlighting the tension between scientific advancement and ethical considerations.
- Ongoing Legal Actions: In 2023, the Lacks family settled with Thermo Fisher Scientific, yet lawsuits against other pharmaceutical companies remain active, demonstrating the family's strong resolve in pursuing justice and compensation for the unauthorized use of Henrietta Lacks' cells.
- Dividend Increase: Thermo Fisher Scientific has declared a quarterly dividend increase from $0.43 to $0.47 per share, representing a 10% rise that not only enhances shareholder returns but also reflects the company's robust cash flow and profitability.
- Yield Information: The forward yield of this dividend stands at 0.37%, indicating the company's stability and attractiveness in the current market environment, which may draw more long-term investors' interest.
- Payment Arrangement: The dividend is payable on April 15, with a record date of March 13 and an ex-dividend date also on March 13, ensuring shareholders receive their returns promptly and bolstering investor confidence.
- Future Outlook: Thermo Fisher anticipates revenue guidance of up to $47.2 billion for 2026, with projected EPS growth of 6% to 8%, while advancing AI initiatives and strategic acquisitions, showcasing the company's proactive strategic positioning for future growth.








