PureTech Health unveils fresh insights from the ELEVATE IPF trial
Presentation of New Data: PureTech Health presented new analyses from the Phase 2b ELEVATE IPF trial of deupirfenidone for idiopathic pulmonary fibrosis at the American College of Chest Physicians annual meeting.
Safety and Efficacy Across Age Groups: The data indicated that deupirfenidone demonstrated a favorable safety and efficacy profile consistent across all age groups, including patients aged 75 and older.
Tolerability in Older Patients: The trial showed that older patients tolerated deupirfenidone comparably to younger patients, with similar rates of treatment emergent adverse events, addressing historical concerns about treatment tolerability in this demographic.
Support for Improved Care: These findings reinforce deupirfenidone's differentiated profile and its potential to significantly enhance treatment options for older patients with idiopathic pulmonary fibrosis.
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PureTech Appoints Robert Lyne as CEO, Focuses on Funding and Innovation
- Leadership Change: PureTech Health plc appoints Robert Lyne as CEO, aiming to leverage his extensive experience in the biotech sector to drive the company's strategic development in innovation and funding.
- Funding Plans: The company plans to secure funding for its newly founded entity, Celea Therapeutics, by the first half of 2026, which is expected to significantly reduce operational costs and enhance shareholder value.
- Capital Efficiency Improvement: Lyne emphasizes a streamlined operational structure and a disciplined investment strategy to ensure efficient capital utilization while advancing key innovation initiatives.
- Strategic Focus: The new CEO will concentrate on optimizing shareholder returns, with plans to evaluate potential capital return methods after Celea is fully financed, ensuring sustained growth in the biopharmaceutical sector.







