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PRTC Overview

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ET
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ET
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Intellectia

Loading chart...

High
16.250
Open
16.250
VWAP
16.25
Vol
575.00
Mkt Cap
392.94M
Low
16.250
Amount
9.34K
EV/EBITDA(TTM)
--
Total Shares
24.18M
EV
58.61M
EV/OCF(TTM)
--
P/S(TTM)
59.40
PureTech Health plc is a clinical-stage company dedicated to giving life to new classes of medicine to change the lives of patients with devastating diseases. The Company is engaged in the development of around 29 therapeutics and therapeutic candidates, including three that have been approved by the United States Food and Drug Administration. A number of these programs are advanced by the Company or its Founded Entities in various indications and stages of clinical development. Its primary programs include LYT-100 and LYT-200. Deupirfenidone (LYT-100) is being developed as a potential new standard of care (SOC) for the treatment of idiopathic pulmonary fibrosis (IPF). LYT-200 is an anti-galectin-9 monoclonal antibody (mAb) being developed for the treatment of hematological malignancies, including acute myeloid leukemia (AML) and high-risk myelodysplastic syndromes (MDS), as well as solid tumors, including head and neck cancers, with a focus on metastatic disease.
Show More

Events Timeline

(ET)
2026-02-19
12:50:00
PureTech Health Receives FDA and EU Orphan Drug Designation
select
2025-12-18 (ET)
2025-12-18
05:20:00
PureTech Health Appoints Robert Lyne as CEO
select
2025-12-08 (ET)
2025-12-08
05:30:00
PureTech Health Completes FDA Phase 2 Meeting, Advances LYT-100 Development
select
2025-10-22 (ET)
2025-10-22
05:24:51
PureTech Health unveils fresh insights from the ELEVATE IPF trial
select
2025-09-11 (ET)
2025-09-11
07:16:10
PureTech Health announces first patient dosed in GlyphAgo study by Seaport Therapeutics
select
2025-08-13 (ET)
2025-08-13
12:18:04
PureTech says Vedanta ulcerative colitis study missed endpoint
select
2025-08-06 (ET)
2025-08-06
09:34:09
DiaMedica Therapeutics CMO Lorianne Masuoka resigns, Julie Krop succeeds
select
2025-07-17 (ET)
2025-07-17
07:15:36
PureTech Health doses first patient in BUOY-1 study
select
2025-07-16 (ET)
2025-07-16
05:23:30
PureTech Health CEO Bharatt Chowrira steps down
select
2025-07-08 (ET)
2025-07-08
12:46:40
PureTech Health says Raju Kucherlapati steps down as board chair
select

News

Businesswire
1.0
02-25Businesswire
PureTech Health to Participate in Healthcare Conference
  • Executive Participation: PureTech Health's CEO Robert Lyne and Co-founder Eric Elenko will participate in the Leerink Partners Global Healthcare Conference on March 11, 2026, showcasing the company's innovations in biotherapeutics.
  • Webcast Availability: The presentation will be available via webcast on PureTech Health's investor website, ensuring that investors and the public can access the latest updates in real-time.
  • Company Strategy Overview: PureTech Health is dedicated to developing therapeutics through a capital-efficient R&D model, having successfully launched three products approved by the U.S. FDA, demonstrating its potential in the biotherapeutics sector.
  • Cautionary Forward-Looking Statements: The press release includes forward-looking statements, highlighting the risks and uncertainties that may affect the company's future plans and strategies, advising investors to consider relevant risk factors.
Businesswire
9.0
02-19Businesswire
PureTech Secures Orphan Drug Designation for Deupirfenidone in IPF Treatment
  • Orphan Drug Designation: PureTech Health announced that its deupirfenidone (LYT-100) has received Orphan Drug Designation from both the FDA and European Commission for treating idiopathic pulmonary fibrosis (IPF), highlighting the drug's potential to address significant unmet medical needs in this rare disease.
  • Clinical Trial Results: In the global Phase 2b ELEVATE IPF trial, participants receiving deupirfenidone 825 mg three times daily experienced a significantly slower decline in lung function, with a 26-week FVC change of -21.5 mL compared to -112.5 mL for placebo, demonstrating the drug's superior efficacy.
  • Future Research Plans: Celea Therapeutics intends to initiate the Phase 3 SURPASS-IPF trial in the first half of 2026, comparing deupirfenidone to the existing treatment pirfenidone, with successful results potentially providing critical data for drug registration.
  • Broad Market Potential: As a next-generation antifibrotic, deupirfenidone may set a new standard of care for IPF and has potential applications in other fibrotic diseases, further solidifying PureTech's leadership in the biotherapeutics sector.
Newsfilter
9.0
02-19Newsfilter
PureTech Secures Orphan Drug Designation for LYT-100, Advancing New Treatment Development
  • Orphan Drug Designation: PureTech Health announced that its LYT-100 has received Orphan Drug Designation from both the FDA and the European Commission, aimed at facilitating the development of therapies for rare diseases, highlighting the urgent need for effective treatments in this patient population.
  • Clinical Trial Results: In the ELEVATE IPF trial, patients receiving LYT-100 825 mg three times daily experienced a significantly slower decline in lung function, with a change in Forced Vital Capacity (FVC) of -21.5 mL at 26 weeks compared to placebo, indicating its potential in treating idiopathic pulmonary fibrosis.
  • Market Demand and Strategic Importance: With only about 25% of idiopathic pulmonary fibrosis patients having received treatment, the development of LYT-100 aims to address this unmet need, potentially providing more effective treatment options and enhancing the company's competitive position in the biopharmaceutical sector.
  • Future Development Plans: Celea Therapeutics plans to initiate the Phase 3 SURPASS-IPF trial in the first half of 2026 to compare LYT-100 with the existing therapy pirfenidone, which, if successful, could establish a pathway for potential market approval and further drive company growth.
Yahoo Finance
5.0
2025-12-18Yahoo Finance
Robert Lyne Appointed CEO of PureTech
  • New CEO Appointment: PureTech Health has appointed Robert Lyne as the new chief executive officer.
  • Announcement Date: The announcement regarding the appointment was made on Thursday.
Businesswire
5.0
2025-12-18Businesswire
PureTech Appoints Robert Lyne as CEO, Focuses on Funding and Innovation
  • Leadership Change: PureTech Health plc appoints Robert Lyne as CEO, aiming to leverage his extensive experience in the biotech sector to drive the company's strategic development in innovation and funding.
  • Funding Plans: The company plans to secure funding for its newly founded entity, Celea Therapeutics, by the first half of 2026, which is expected to significantly reduce operational costs and enhance shareholder value.
  • Capital Efficiency Improvement: Lyne emphasizes a streamlined operational structure and a disciplined investment strategy to ensure efficient capital utilization while advancing key innovation initiatives.
  • Strategic Focus: The new CEO will concentrate on optimizing shareholder returns, with plans to evaluate potential capital return methods after Celea is fully financed, ensuring sustained growth in the biopharmaceutical sector.
Newsfilter
5.0
2025-12-18Newsfilter
PureTech Appoints Robert Lyne as CEO, Focuses on Funding and Innovation
  • Leadership Change: PureTech Health has appointed Robert Lyne as CEO, aiming to leverage his extensive experience in life sciences to drive the company's strategic execution in biotherapeutic innovation.
  • Funding Plans: The company plans to secure funding for Celea Therapeutics by the first half of 2026, which is expected to significantly reduce operational costs and enhance capital return rates.
  • Innovation Strategy: Lyne emphasized a streamlined structure and capital-efficient innovation strategy to ensure sustainable shareholder value at key inflection points.
  • Market Positioning: The appointment of the new CEO is viewed as a critical step in optimizing shareholder returns, demonstrating the company's commitment to maintaining competitiveness in the rapidly evolving biopharmaceutical market.

Valuation Metrics

The current forward P/E ratio for PureTech Health PLC (PRTC.O) is -5.62, compared to its 5-year average forward P/E of -5.46. For a more detailed relative valuation and DCF analysis to assess PureTech Health PLC's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.46
Current PE
-5.62
Overvalued PE
-2.98
Undervalued PE
-7.94

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.05
Current EV/EBITDA
-1.62
Overvalued EV/EBITDA
-0.77
Undervalued EV/EBITDA
-5.32

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
64.71
Current PS
0.00
Overvalued PS
115.98
Undervalued PS
13.45

Financials

AI Analysis
Annual
Quarterly

Whales Holding PRTC

J
JM Finn & Co Ltd.
Holding
PRTC
+17.53%
3M Return
T
Tang Capital Management, LLC
Holding
PRTC
-3.19%
3M Return
L
Lansdowne Partners Limited
Holding
PRTC
-3.41%
3M Return
P
Pentwater Capital Management LP
Holding
PRTC
-5.89%
3M Return
I
Interactive Brokers Group, Inc.
Holding
PRTC
-6.07%
3M Return

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Frequently Asked Questions

What is PureTech Health PLC (PRTC) stock price today?

The current price of PRTC is 16.25 USD — it has increased 0

What is PureTech Health PLC (PRTC)'s business?

PureTech Health plc is a clinical-stage company dedicated to giving life to new classes of medicine to change the lives of patients with devastating diseases. The Company is engaged in the development of around 29 therapeutics and therapeutic candidates, including three that have been approved by the United States Food and Drug Administration. A number of these programs are advanced by the Company or its Founded Entities in various indications and stages of clinical development. Its primary programs include LYT-100 and LYT-200. Deupirfenidone (LYT-100) is being developed as a potential new standard of care (SOC) for the treatment of idiopathic pulmonary fibrosis (IPF). LYT-200 is an anti-galectin-9 monoclonal antibody (mAb) being developed for the treatment of hematological malignancies, including acute myeloid leukemia (AML) and high-risk myelodysplastic syndromes (MDS), as well as solid tumors, including head and neck cancers, with a focus on metastatic disease.

What is the price predicton of PRTC Stock?

Wall Street analysts forecast PRTC stock price to fall over the next 12 months. According to Wall Street analysts, the average 1-year price target for PRTC is USD with a low forecast of USD and a high forecast of USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is PureTech Health PLC (PRTC)'s revenue for the last quarter?

PureTech Health PLC revenue for the last quarter amounts to NaN USD, decreased

What is PureTech Health PLC (PRTC)'s earnings per share (EPS) for the last quarter?

PureTech Health PLC. EPS for the last quarter amounts to USD, decreased

How many employees does PureTech Health PLC (PRTC). have?

PureTech Health PLC (PRTC) has 56 emplpoyees as of March 21 2026.

What is PureTech Health PLC (PRTC) market cap?

Today PRTC has the market capitalization of 392.94M USD.