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PRTC Overview

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ET
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ET
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Intellectia

Loading chart...

High
17.420
Open
17.110
VWAP
17.10
Vol
35.78K
Mkt Cap
417.22M
Low
16.740
Amount
611.79K
EV/EBITDA(TTM)
--
Total Shares
24.34M
EV
144.96M
EV/OCF(TTM)
--
P/S(TTM)
89.62
PureTech Health plc is a clinical-stage company dedicated to giving life to new classes of medicine to change the lives of patients with devastating diseases. The Company is engaged in the development of around 29 therapeutics and therapeutic candidates, including three that have been approved by the United States Food and Drug Administration. A number of these programs are advanced by the Company or its Founded Entities in various indications and stages of clinical development. Its primary programs include LYT-100 and LYT-200. Deupirfenidone (LYT-100) is being developed as a potential new standard of care (SOC) for the treatment of idiopathic pulmonary fibrosis (IPF). LYT-200 is an anti-galectin-9 monoclonal antibody (mAb) being developed for the treatment of hematological malignancies, including acute myeloid leukemia (AML) and high-risk myelodysplastic syndromes (MDS), as well as solid tumors, including head and neck cancers, with a focus on metastatic disease.
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Events Timeline

(ET)
2026-04-29
05:30:00
PureTech Health Announces Voluntary Delisting of American Depositary Shares
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2026-04-22 (ET)
2026-04-22
07:20:00
PureTech Health Announces Positive Data from LYT-200 Clinical Trial
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2026-04-02 (ET)
2026-04-02
08:30:00
PureTech Health Announces ELEVATE IPF Trial Results
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2026-04-02
07:20:00
PureTech Health's Seaport Therapeutics Advances GlyphAgo Clinical Trials
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2026-02-19 (ET)
2026-02-19
12:50:00
PureTech Health Receives FDA and EU Orphan Drug Designation
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2025-12-18 (ET)
2025-12-18
05:20:00
PureTech Health Appoints Robert Lyne as CEO
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2025-12-08 (ET)
2025-12-08
05:30:00
PureTech Health Completes FDA Phase 2 Meeting, Advances LYT-100 Development
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2025-10-22 (ET)
2025-10-22
05:24:51
PureTech Health unveils fresh insights from the ELEVATE IPF trial
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2025-09-11 (ET)
2025-09-11
07:16:10
PureTech Health announces first patient dosed in GlyphAgo study by Seaport Therapeutics
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2025-08-13 (ET)
2025-08-13
12:18:04
PureTech says Vedanta ulcerative colitis study missed endpoint
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News

seekingalpha
8.5
04-29seekingalpha
PureTech Announces Voluntary Delisting Plan
  • Financial Update: As of December 31, 2025, PureTech reported consolidated cash, cash equivalents, and short-term investments totaling $277.3 million, which decreased to $248.1 million by March 31, 2026, indicating a decline in liquidity that may impact future investment capabilities.
  • Delisting Notification: PureTech has notified Nasdaq of its intention to voluntarily delist, which means the company will no longer trade on the U.S. market, potentially raising concerns among investors regarding liquidity and market visibility, thereby affecting shareholder confidence.
  • Change of Trading Venue: Despite the delisting from Nasdaq, PureTech's ordinary shares will continue to be listed on the London Stock Exchange, indicating a strategic shift towards the European market, which may better serve its primary investor base.
  • IPO Developments: Concurrently, PureTech's neuropsychiatric drug development subsidiary, Seaport, has filed for a U.S. IPO, which could provide new funding sources for the company, although the overall market environment remains uncertain.
Newsfilter
9.5
04-29Newsfilter
PureTech Health Reports 2025 Financial Results and Strategic Update
  • Financial Overview: As of December 31, 2025, PureTech reported total cash and short-term investments of $277 million, indicating sufficient funding to support operations through at least the end of 2028, which enhances investor confidence.
  • Product Development Progress: Celea Therapeutics' deupirfenidone is ready to enter Phase 3 clinical trials, with financing expected to close in early Q3 2026, which could significantly enhance the company's market position in idiopathic pulmonary fibrosis if successful.
  • Strategic Restructuring Plan: The company plans to voluntarily delist from Nasdaq and focus on its listing on the London Stock Exchange to simplify its structure and reduce costs, which is expected to improve operational efficiency and enhance engagement with investors.
  • Commitment to Shareholder Returns: PureTech commits to returning a greater proportion of future cash generation to shareholders, particularly in the event of outsized returns, demonstrating the company's focus on shareholder value.
Newsfilter
5.0
04-27Newsfilter
Seaport Therapeutics Appoints Dr. Sharon Mates to Board of Directors
  • New Board Member: Seaport Therapeutics has appointed Dr. Sharon Mates to its Board of Directors; she previously co-founded and served as CEO of Intra-Cellular Therapies, leading the company to a $14.6 billion acquisition by Johnson & Johnson in 2025, showcasing her exceptional leadership in the biopharmaceutical sector.
  • Extensive Industry Experience: Dr. Mates brings decades of experience in neuropsychiatry, having successfully commercialized CAPLYTA® and continued its market growth post-acquisition by J&J, which is expected to significantly support Seaport's mission.
  • Strategic Collaboration Outlook: Dr. Mates expressed great interest in Seaport's programs and looks forward to collaborating closely with founder Daphne Zohar and other team members to drive the company's continued growth and develop life-changing treatments for patients.
  • Innovative Drug Development: Seaport Therapeutics focuses on developing new medicines for depression, anxiety, and other neuropsychiatric disorders, and Dr. Mates' addition is anticipated to enhance the company's R&D capabilities, helping it stand out in a competitive market.
seekingalpha
8.5
04-11seekingalpha
Seaport Therapeutics Files for IPO to Develop Neuropsychiatric Drugs
  • IPO Filing Submitted: Seaport Therapeutics (SPTX) has filed for an initial public offering with the SEC, aiming to list on the Nasdaq under the symbol 'SPTX', marking a significant step for the company in terms of financing and market expansion.
  • Funding Utilization: The proceeds from the IPO will be allocated to multiple operational activities, particularly for R&D related to its lead asset GlyphAllo, an oral prodrug aimed at treating major depressive disorder, demonstrating the company's commitment to drug development.
  • Clinical Trial Progress: GlyphAllo is currently undergoing a Phase 2 trial named BUOY-1, with topline results expected in H1 2027, which will have a substantial impact on the company's future development and market positioning.
  • Financial Overview: As of December 31, 2025, Seaport reported an accumulated deficit of $114.1 million, with a net loss in 2025 rising approximately 60% year-over-year to $74.9 million, indicating challenges in profitability despite significant R&D potential.
Newsfilter
9.0
04-02Newsfilter
Deupirfenidone Shows Significant Efficacy in Idiopathic Pulmonary Fibrosis
  • Significant Efficacy: In a 26-week clinical trial, deupirfenidone 825 mg TID monotherapy significantly slowed lung function decline in patients with idiopathic pulmonary fibrosis, with an adjusted mean FVC difference of 91 mL (p=0.02), approaching the lung function changes expected in healthy aging, indicating its potential in treatment.
  • Standard Treatment Comparison: This trial is the first industry-sponsored IPF trial to include a current standard-of-care treatment as an active comparator, enhancing the interpretability of efficacy and safety findings and laying a solid foundation for the upcoming Phase 3 SURPASS-IPF trial.
  • Financing Plans: PureTech's subsidiary, Celea Therapeutics, is working to complete financing to initiate the Phase 3 SURPASS-IPF trial in the first half of 2026, aiming to further validate the efficacy of deupirfenidone and push it towards becoming a new standard of care.
  • Drug Exposure and Tolerability: Deupirfenidone 825 mg TID showed approximately 50% greater drug exposure compared to pirfenidone 801 mg TID, yet the incidence of adverse events was similar (85.9% vs 84.1%), demonstrating its ability to enhance efficacy while maintaining good tolerability.
Newsfilter
9.0
04-02Newsfilter
Seaport Therapeutics Announces Positive Clinical Data for GlyphAgo
  • Clinical Trial Success: Seaport Therapeutics reported positive topline data from its GlyphAgo clinical trial, demonstrating a 6.8-fold increase in bioavailability compared to unmodified agomelatine, exceeding the expected 2-fold target, indicating GlyphAgo's potential in treating generalized anxiety disorder (GAD).
  • Good Safety Profile: GlyphAgo exhibited good tolerability across all evaluated doses in the trial, with no serious adverse events or liver-related side effects reported, enhancing its safety profile and potential market acceptance.
  • Follow-up Trial Plans: Based on the trial results, Seaport plans to advance GlyphAgo into two parallel clinical trials, including a Phase 2a trial to assess its potential sleep benefits in GAD patients and a registration-enabling Phase 2b randomized controlled trial, further validating its clinical application.
  • Platform Advantages: GlyphAgo leverages Seaport's Glyph platform to avoid first-pass liver metabolism, enhancing systemic exposure to agomelatine while reducing liver exposure risks, positioning it as a leading treatment option for GAD and addressing unmet market needs.

Valuation Metrics

The current forward P/E ratio for PureTech Health PLC (PRTC.O) is 0.00, compared to its 5-year average forward P/E of -5.22. For a more detailed relative valuation and DCF analysis to assess PureTech Health PLC's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.22
Current PE
0.00
Overvalued PE
-3.18
Undervalued PE
-7.27

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-2.85
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
-0.87
Undervalued EV/EBITDA
-4.84

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
62.62
Current PS
0.00
Overvalued PS
112.75
Undervalued PS
12.48

Financials

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Whales Holding PRTC

T
Tang Capital Management, LLC
Holding
PRTC
+3.72%
3M Return
L
Lansdowne Partners Limited
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+2.51%
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I
Interactive Brokers Group, Inc.
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-1.98%
3M Return

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Frequently Asked Questions

What is PureTech Health PLC (PRTC) stock price today?

The current price of PRTC is 17.14 USD — it has increased 1

What is PureTech Health PLC (PRTC)'s business?

PureTech Health plc is a clinical-stage company dedicated to giving life to new classes of medicine to change the lives of patients with devastating diseases. The Company is engaged in the development of around 29 therapeutics and therapeutic candidates, including three that have been approved by the United States Food and Drug Administration. A number of these programs are advanced by the Company or its Founded Entities in various indications and stages of clinical development. Its primary programs include LYT-100 and LYT-200. Deupirfenidone (LYT-100) is being developed as a potential new standard of care (SOC) for the treatment of idiopathic pulmonary fibrosis (IPF). LYT-200 is an anti-galectin-9 monoclonal antibody (mAb) being developed for the treatment of hematological malignancies, including acute myeloid leukemia (AML) and high-risk myelodysplastic syndromes (MDS), as well as solid tumors, including head and neck cancers, with a focus on metastatic disease.

What is the price predicton of PRTC Stock?

Wall Street analysts forecast PRTC stock price to fall over the next 12 months. According to Wall Street analysts, the average 1-year price target for PRTC is USD with a low forecast of USD and a high forecast of USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is PureTech Health PLC (PRTC)'s revenue for the last quarter?

PureTech Health PLC revenue for the last quarter amounts to NaN USD, decreased

What is PureTech Health PLC (PRTC)'s earnings per share (EPS) for the last quarter?

PureTech Health PLC. EPS for the last quarter amounts to USD, decreased

How many employees does PureTech Health PLC (PRTC). have?

PureTech Health PLC (PRTC) has 61 emplpoyees as of May 10 2026.

What is PureTech Health PLC (PRTC) market cap?

Today PRTC has the market capitalization of 417.22M USD.