Pulse Biosciences Appoints Liane Teplitsky as COO
Pulse Biosciences announced the strengthening of its executive leadership team with the appointment of Liane Teplitsky as Chief Operating Officer and expanded role of Dr. David Kenigsberg as full-time Chief Medical Officer. Both the appointment of Liane Teplitsky as Chief Operating Officer and Dr. David Kenigsberg's agreement to serve as the Company's Chief Medical Officer on a full-time basis further enhance the Company's strategic alignment to prioritize and accelerate the development and future commercialization of its nPulse Cardiac Catheter Ablation System. As COO, Teplitsky will oversee the Company's Clinical, Regulatory, Quality, and Commercial functions. Teplitsky most recently served as Chief Executive Officer of Artedrone. The Company also announced that David Kenigsberg, MD, FACC, FHRS, Chief Medical Officer of Pulse Biosciences, will expand his role, while maintaining his active routine clinical practice. His increased leadership capacity will benefit the Company as it advances its IDE pivotal clinical study evaluating the nPulse Cardiac Catheter System for the treatment of atrial fibrillation.
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- Executive Appointment: Pulse Biosciences has appointed Liane Teplitsky as Chief Operating Officer, bringing 20 years of experience in medical technology, including her recent role as CEO of Artedrone, which is expected to enhance operational efficiency and market expansion.
- Role Expansion: David Kenigsberg's role has been expanded to full-time Chief Medical Officer, indicating the company's commitment to strengthening its medical leadership, aimed at enhancing product development and clinical strategy to support future business growth.
- Market Performance: In pre-market trading, PLSE shares were priced at $19, down 0.31%, reflecting a cautious market sentiment regarding the company's new appointments, which may impact investor confidence.
- Industry Background: Teplitsky has held senior marketing and commercial leadership roles at Abbott Laboratories and St. Jude Medical, and her extensive industry experience is expected to bring new perspectives and strategic direction to Pulse Biosciences.

- Trial Launch: Pulse Biosciences has enrolled the first patients in its pivotal U.S. study NANOPULSE-AF, marking a significant advancement in its atrial fibrillation program, with plans to recruit approximately 215 participants to evaluate the safety and effectiveness of its nPulse Cardiac Catheter System.
- High Success Rate: The system achieved a 96% procedural success rate in its European first-in-human feasibility study without the need for anti-arrhythmic drugs, indicating its potential to transform traditional catheter ablation methods for atrial fibrillation treatment.
- Technological Edge: The nPulse system utilizes nanosecond pulsed field ablation technology, achieving a median left atrial dwell time of 21 minutes and a total procedure time of about 65 minutes, significantly enhancing treatment efficiency while minimizing collateral damage to surrounding cardiac tissue.
- Market Potential: The CTO of Pulse Biosciences noted that the first patient enrollment represents an important step based on early feasibility results, and the company will continue to explore applications of this technology in other soft-tissue ablation markets, further solidifying its market position.
- Study Launch: Pulse Biosciences has successfully enrolled the first patients at St. Bernards Medical Center in Arkansas, marking the initiation of the NANOPULSE-AF study aimed at evaluating the efficacy of its nPulse™ Cardiac Catheter System for treating drug-resistant paroxysmal atrial fibrillation.
- Exceptional Success Rates: The prior feasibility study demonstrated a 96% procedural success rate and 100% acute success at 12 months for the nPulse™ technology, significantly surpassing the typical 20-25% recurrence rates associated with conventional treatments, highlighting its potential in atrial fibrillation management.
- Integrated Technological Advantages: The nPulse™ system is tightly integrated with Abbott's EnSite X 3D electroanatomical mapping system, providing real-time 3D visualization that enhances catheter navigation and contact assessment, thereby improving treatment accuracy and efficiency, which is expected to transform atrial fibrillation treatment paradigms.
- Future Development Plans: The NANOPULSE-AF study plans to enroll approximately 215 participants across up to 30 centers in the U.S. and Europe, with primary endpoints assessed at 6 and 12 months post-ablation to support the broader clinical development of the nPulse™ system.
- Clinical Study Results: Pulse Biosciences has decided to accelerate the development of its Pulse Cardiac Catheter Ablation System based on a European feasibility study that indicates its Nanosecond Pulsed Field Ablation technology offers a unique combination of speed, safety, and long-term efficacy in treating Atrial Fibrillation.
- Efficacy Data: The study revealed that at 12 months, 45 out of 47 patients (96%) achieved durable pulmonary vein isolation, significantly lower than the typical 20%-25% recurrence rate, highlighting the clinical advantages of this technology.
- R&D Investment Focus: Pulse Biosciences stated that the majority of its R&D and clinical investments will now be directed towards the upcoming pivotal IDE study and related regulatory submissions, aiming to expedite the product's market entry.
- Market Outlook: With advancements in the nPulse platform's clinical milestones, Pulse Biosciences plans to target CE Mark submission in 2026, further solidifying its market position in cardiac treatment.
- Breakthrough Clinical Data: Pulse Biosciences' European feasibility study involving 150 patients demonstrated a 100% procedural success rate, with all 75 evaluable patients achieving acute Pulmonary Vein Isolation, indicating the potential to transform clinical practices in atrial fibrillation treatment.
- Significant Long-term Efficacy: Follow-up at 12 months revealed a 96% sustained success rate for Pulmonary Vein Isolation, significantly exceeding the traditional 20-25% recurrence rates, suggesting a strong market acceptance for this innovative treatment.
- Strategic Resource Realignment: The company is reallocating the majority of its R&D and clinical investments to focus on the nPulse Cardiac Catheter program, planning pivotal IDE studies in the U.S. and Europe, reflecting a strong commitment to the electrophysiology market and aiming for expedited product commercialization.
- Upcoming Milestones: Pulse Biosciences is set to present late-breaking clinical data on AFib treatment at the 2026 Heart Rhythm Conference, which is expected to further validate the efficacy and safety of its technology, potentially attracting significant investor and medical community interest.
- Clinical Data Breakthrough: Pulse Biosciences' European feasibility study involving 150 patients demonstrated a 100% procedural success rate, with all 75 evaluable patients achieving acute Pulmonary Vein Isolation (PVI), indicating the potential to transform clinical practices in atrial fibrillation treatment.
- Significant Long-Term Efficacy: Follow-up at 12 months revealed a 96% sustained success rate for PVI, significantly exceeding the traditional 20-25% recurrence rates, thereby establishing the technology's leading position in the electrophysiology field.
- Strategic Resource Realignment: The company is reallocating the majority of its R&D and clinical investments to the upcoming pivotal IDE study for the nPulse Cardiac Catheter in the U.S. and Europe, aiming to accelerate market development and optimize capital allocation to seize high-value growth opportunities.
- Upcoming Milestones: Late-breaking clinical data on the nPulse Cardiac Catheter System will be presented at the Heart Rhythm 2026 conference, further validating its efficacy in treating atrial fibrillation and likely attracting increased investor interest.









