Mirum and Incyte to Present Zilurgisertib Study Results at ENDO 2026
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jun 04 2026
0mins
Mirum Pharmaceuticals (MIRM) and Incyte (INCY) announced that Phase 2 results from the PROGRESS study evaluating zilurgisertib, an investigational ALK2 inhibitor, in patients with fibrodysplasia ossificans progressiva will be presented at ENDO 2026, the Endocrine Society's annual meeting, taking place June 13-16, 2026, in Chicago, Illinois. "ENDO 2026 is an important milestone for the zilurgisertib FOP program as we share pivotal results from the PROGRESS study in patients living with this debilitating disease," said Steven Stein, M.D., Executive Vice President, Chief Medical Officer and Head of Late-stage Development at Incyte. "These data add to the growing clinical understanding of zilurgisertib's potential in FOP as Incyte and Mirum continue to advance toward the FDA's Priority Review PDUFA date of September 26, 2026."
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Analyst Views on INCY
Wall Street analysts forecast INCY stock price to fall
19 Analyst Rating
9 Buy
9 Hold
1 Sell
Moderate Buy
Current: 107.830
Low
73.00
Averages
100.31
High
125.00
Current: 107.830
Low
73.00
Averages
100.31
High
125.00
About INCY
Incyte Corporation is a biopharmaceutical company, which is engaged in the discovery, development, and commercialization of therapeutics. The Company operates in three therapeutic areas: Hematology, Oncology, and Inflammation and Autoimmunity (IAI). Its hematology franchise includes four approved products, JAKAFI (ruxolitinib), ICLUSIG (ponatinib), MONJUVI (tafasitamab-cxix)/MINJUVI (tafasitamab) and NIKTIMVO (axatilimab-csfr), as well as multiple clinical development programs. Its oncology franchise includes two approved products, PEMAZYRE (pemigatinib) and ZYNYZ (retifanlimab-dlwr), as well as several clinical development programs. Its Inflammation and Autoimmunity franchise is comprised of one approved product, OPZELURA (ruxolitinib) cream, with several clinical programs in development. The Company manages business activities on a consolidated basis through the development and commercialization of oncology and dermatology products.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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See More
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See More
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- Increased Market Volatility: The decline of the uranium ETF, combined with overall market fluctuations, may prompt investors to reassess their investment strategies in the nuclear energy sector, thereby impacting the stock performance of related companies.
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See More
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- Significant Treatment Effect: Compared to the standard R-CHOP regimen, Monjuvi combined with R-CHOP and enalidomide reduces the risk of disease progression or death by 25%, indicating its substantial potential in improving patient outcomes.
- Urgent Market Demand: Despite R-CHOP being the standard first-line therapy, nearly 40% of patients experience disease progression or relapse after initial treatment, highlighting the necessity and demand for innovative therapies in this space.
- Regulatory Application Prospects: Incyte plans to leverage existing frontMIND data to support global regulatory submissions seeking to incorporate Monjuvi and enalidomide into R-CHOP for newly diagnosed DLBCL cases, further expanding its market share.
See More
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- Significant Efficacy Improvement: The frontMIND study demonstrated that the Tafa-Len-R-CHOP treatment group achieved a 25% reduction in the risk of disease progression compared to the R-CHOP group (HR 0.75), indicating a clinically meaningful benefit for high-risk lymphoma patients.
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See More
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- New Drug Targets: The collaboration adds at least five new drug targets, granting Incyte exclusive rights to develop and commercialize any resulting drug products, indicating a strategic advantage in new drug development.
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See More
