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XNCR Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
12.600
Open
12.600
VWAP
12.30
Vol
490.00K
Mkt Cap
902.80M
Low
11.980
Amount
6.03M
EV/EBITDA(TTM)
--
Total Shares
73.34M
EV
484.35M
EV/OCF(TTM)
--
P/S(TTM)
7.35
Xencor, Inc. is a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases. It has more than 20 candidates engineered with its XmAb technology that are in clinical development, and multiple XmAb medicines are marketed by partners. Its XmAb engineering technology enables small changes to a protein structure that result in new mechanisms of therapeutic action. Its wholly-owned development candidates include XmAb942, XmAb819, XmAb808, and XmAb541. Candidates co-developed with partners include Plamotamab. Its clinical-stage drug candidates advanced by partners include Xaluritamig (AMG 509), ASP2138, JNJ-9401, JNJ-1493, Xpro1595, Obexelimab, and Novartis XmAb, an undisclosed antibody candidate. Its cytokine drug candidates in clinical development consist of efbalropendekin alfa (XmAb306/RG6323). Its Vudalimab is a bispecific antibody that targets PD-1 and CTLA-4.
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Events Timeline

(ET)
2026-03-24
16:20:00
Major Averages Close Lower as Oil Surges Above $90
select
2026-03-24
12:00:00
Dow Jones Up 0.31% to 46,350.65 Points
select
2026-03-09 (ET)
2026-03-09
16:10:00
Xencor Terminates Collaboration Agreement with Genentech
select
link
2026-03-08 (ET)
2026-03-08
22:30:00
KKR Plans to Sell CoolIT Systems for Over $3B
select
2026-03-08
17:00:00
Dr. Vinay Prasad to Leave Agency at End of April
select
link
2026-03-04 (ET)
2026-03-04
16:10:00
Xencor Expects Cash to Reach $380M to $400M by 2026
select

News

NASDAQ.COM
4.5
03-24NASDAQ.COM
US Stocks Decline Amid Ongoing Iran Conflict
  • Market Performance: On Tuesday, the S&P 500 Index fell by 0.37%, the Dow Jones Industrial Average decreased by 0.18%, and the Nasdaq 100 Index dropped by 0.77%, reflecting investor concerns over the ongoing conflict in Iran and a general decline in market sentiment.
  • Oil Price Fluctuations: WTI crude oil prices surged over 4%, reaching elevated levels due to Iran's missile and drone strikes on Israel and US bases, raising fears about energy supply disruptions that could impact global economic recovery.
  • Economic Data: Despite market pressures, Q4 nonfarm productivity remained at 1.8%, while unit labor costs were revised up to 4.4%, exceeding expectations, indicating resilience in the economic fundamentals that may provide some support to the stock market.
  • International Tensions: Reports of Saudi Arabia and the UAE aligning with the Iran conflict have heightened market anxiety, as investors are closely monitoring the potential for increased US military deployment, which could escalate tensions and affect global market stability.
NASDAQ.COM
4.5
03-24NASDAQ.COM
US Stocks Decline Amid Ongoing Iran Conflict
  • Market Movement: The S&P 500 Index is down 0.16%, while the Dow Jones Industrial Average is up 0.13%, and the Nasdaq 100 Index has decreased by 0.50%, reflecting investor concerns over the ongoing Iran conflict, which is dampening market sentiment.
  • Rising Energy Prices: WTI crude oil prices have surged over 4% due to Iran's missile strikes on Israel and US bases, which not only limits stock market declines but also raises inflation expectations, potentially influencing future monetary policy decisions.
  • Economic Data Performance: The US Q4 nonfarm productivity remained unchanged at 1.8%, while unit labor costs were revised up to 4.4% from 2.8%, exceeding market expectations, indicating economic resilience that may support the stock market.
  • International Tensions Impact: Saudi Arabia and the UAE have taken steps toward joining the Iran war, potentially escalating the conflict, which increases market concerns about future geopolitical risks and drives investors towards safer assets.
NASDAQ.COM
4.5
03-24NASDAQ.COM
US Stocks Decline Amid Ongoing Iran Conflict
  • Market Decline: The S&P 500 Index fell by 0.80%, the Dow Jones Industrial Average by 0.83%, and the Nasdaq 100 by 0.98%, reflecting investor concerns over the ongoing Iran conflict, which may dampen market sentiment and affect short-term investment decisions.
  • Rising Oil Prices: WTI crude oil prices surged over 4% due to Iran's missile strikes on Israel and US bases, exacerbating global supply chain tensions and potentially raising inflation expectations in the coming months, which could influence the Fed's monetary policy.
  • Mixed Economic Data: Q4 nonfarm productivity remained unchanged at 1.8%, but unit labor costs were revised up to 4.4% from 2.8%, exceeding market expectations, indicating rising labor costs that may pressure corporate profits and subsequently impact stock market performance.
  • International Tensions: Saudi Arabia and the UAE have taken steps toward joining the Iran war, potentially escalating the conflict, and the high uncertainty surrounding future developments will continue to affect investor confidence and market volatility.
seekingalpha
9.5
03-05seekingalpha
Xencor Lowers Outlook After Royalty Dispute
  • Stock Price Decline: Xencor (XNCR) shares fell approximately 8% on Thursday, primarily due to the company's lowered outlook following a royalty dispute with AstraZeneca's subsidiary Alexion Pharmaceuticals, indicating market concerns about future earnings.
  • Royalty Revenue Adjustment: Xencor stated that Alexion has informed the company it will no longer owe additional royalties related to Ultomiris net sales in the U.S., although payments for sales outside the U.S. will continue, potentially leading to future revenue uncertainty.
  • Cash Flow Forecast Downgrade: The company updated its year-end cash guidance, projecting cash, cash equivalents, and marketable debt securities to reach $380 million to $400 million by year-end, down from the previous estimate of $400 million to $430 million, reflecting a cautious outlook on future operations.
  • Shortened Operating Runway: Xencor's revised operating runway forecast has also been shortened, now expected to last until mid-2028, down from prior guidance, indicating increased financial pressure on the company amid the royalty dispute.
Benzinga
9.5
03-05Benzinga
Xencor Lowers Revenue Outlook for Ultomiris Royalties
  • Revenue Outlook Revision: Xencor Inc. announced a revision of its revenue outlook for royalties tied to Ultomiris, as Alexion Pharmaceuticals stated it does not owe additional royalties on Ultomiris sales, which will directly impact Xencor's future cash flow and profitability.
  • Cash Flow Forecast Adjustment: Xencor lowered its 2026 cash outlook from $400 million–$430 million to $380 million–$400 million, although it still expects its cash runway to support operations into mid-2028, indicating some financial pressure on the company.
  • Analyst Perspective: William Blair holds a slightly negative view on Xencor's outlook, yet anticipates that clinical trial updates in 2026 will serve as more impactful catalysts, thus reiterating an Outperform rating, reflecting cautious optimism about the company's long-term potential.
  • Technical Analysis Signals: Xencor's stock is currently trading below its 20-day and 100-day simple moving averages, indicating short-term weakness; despite an 83% increase in share price over the past 12 months, the mixed signals from RSI and MACD suggest investors should proceed with caution.
seekingalpha
9.5
02-25seekingalpha
Xencor Q4 Earnings Beat Expectations Despite Revenue Decline
  • Earnings Beat: Xencor reported a Q4 GAAP EPS of -$0.09, surpassing expectations by $0.50, indicating resilience in profitability despite ongoing financial challenges.
  • Significant Revenue Decline: The company’s revenue of $28.24 million represents a 46.5% year-over-year decrease, missing market expectations, which may impact investor confidence in a competitive biopharmaceutical landscape.
  • Strong Cash Reserves: As of December 31, 2025, Xencor held $610.8 million in cash, cash equivalents, and marketable securities, down from $706.7 million in 2024, reflecting cautious financial management amid operational challenges.
  • Optimistic Partnership Outlook: The late-stage trial success of the lymphoma therapy partnered with Incyte, along with its EU approval, suggests potential growth opportunities for Xencor in drug development and market expansion.
Wall Street analysts forecast XNCR stock price to rise
5 Analyst Rating
Wall Street analysts forecast XNCR stock price to rise
4 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
20.00
Averages
26.25
High
30.00
Current: 0.000
sliders
Low
20.00
Averages
26.25
High
30.00
JPMorgan
Overweight -> Neutral
downgrade
$18 -> $13
AI Analysis
2026-03-24
Reason
JPMorgan
Price Target
$18 -> $13
AI Analysis
2026-03-24
downgrade
Overweight -> Neutral
Reason
JPMorgan downgraded Xencor to Neutral from Overweight with a price target of $13, down from $18. The firm views the company's 2026 as an "execution year." Xencor's pipeline will need time to develop, the analyst tells investors in a research note.
JPMorgan
Overweight
to
Neutral
downgrade
$18 -> $13
2026-03-24
Reason
JPMorgan
Price Target
$18 -> $13
2026-03-24
downgrade
Overweight
to
Neutral
Reason
JPMorgan downgraded Xencor to Neutral from Overweight with a price target of $13, down from $18. The firm sees 2026 as more of a clinical execution year for Xencor. XmAb819's first clear cell renal cell carcinoma data were "encouraging," but questions remain on differentiation in the post immuno-oncology setting and the ability to combine and secure a spot in earlier lines, the analyst tells investors in a research note. JPMorgan believes Xencor needs greater clarity "on the pace of execution and truly needle-moving catalysts" for the shares to move higher. As such, it expects the shares to be range-bound.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for XNCR
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Valuation Metrics

The current forward P/E ratio for Xencor Inc (XNCR.O) is 68.03, compared to its 5-year average forward P/E of -5.51. For a more detailed relative valuation and DCF analysis to assess Xencor Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.51
Current PE
68.03
Overvalued PE
12.85
Undervalued PE
-23.87

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-4.19
Current EV/EBITDA
-3.99
Overvalued EV/EBITDA
12.22
Undervalued EV/EBITDA
-20.60

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
13.88
Current PS
6.35
Overvalued PS
19.97
Undervalued PS
7.78

Financials

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Whales Holding XNCR

T
TCG Crossover Management, LLC
Holding
XNCR
+13.34%
3M Return
E
EcoR1 Capital, LLC
Holding
XNCR
+11.21%
3M Return
B
BVF Partners L.P.
Holding
XNCR
+1.76%
3M Return
R
RTW Investments, LP
Holding
XNCR
-1.91%
3M Return

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Frequently Asked Questions

What is Xencor Inc (XNCR) stock price today?

The current price of XNCR is 12.31 USD — it has decreased -1.05

What is Xencor Inc (XNCR)'s business?

Xencor, Inc. is a clinical-stage biopharmaceutical company developing engineered antibodies for the treatment of cancer and autoimmune diseases. It has more than 20 candidates engineered with its XmAb technology that are in clinical development, and multiple XmAb medicines are marketed by partners. Its XmAb engineering technology enables small changes to a protein structure that result in new mechanisms of therapeutic action. Its wholly-owned development candidates include XmAb942, XmAb819, XmAb808, and XmAb541. Candidates co-developed with partners include Plamotamab. Its clinical-stage drug candidates advanced by partners include Xaluritamig (AMG 509), ASP2138, JNJ-9401, JNJ-1493, Xpro1595, Obexelimab, and Novartis XmAb, an undisclosed antibody candidate. Its cytokine drug candidates in clinical development consist of efbalropendekin alfa (XmAb306/RG6323). Its Vudalimab is a bispecific antibody that targets PD-1 and CTLA-4.

What is the price predicton of XNCR Stock?

Wall Street analysts forecast XNCR stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for XNCR is26.25 USD with a low forecast of 20.00 USD and a high forecast of 30.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Xencor Inc (XNCR)'s revenue for the last quarter?

Xencor Inc revenue for the last quarter amounts to 28.24M USD, decreased -59.67

What is Xencor Inc (XNCR)'s earnings per share (EPS) for the last quarter?

Xencor Inc. EPS for the last quarter amounts to -0.09 USD, decreased -87.67

How many employees does Xencor Inc (XNCR). have?

Xencor Inc (XNCR) has 260 emplpoyees as of April 08 2026.

What is Xencor Inc (XNCR) market cap?

Today XNCR has the market capitalization of 902.80M USD.