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MIRM Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
107.710
Open
104.480
VWAP
106.39
Vol
1.58M
Mkt Cap
6.53B
Low
104.345
Amount
167.76M
EV/EBITDA(TTM)
--
Total Shares
60.98M
EV
6.46B
EV/OCF(TTM)
--
P/S(TTM)
10.21
Mirum Pharmaceuticals, Inc. is a biopharmaceutical company. The Company is focused on the treatment of rare diseases affecting children and adults. It has three medicines: LIVMARLI (maralixibat) oral solution (Livmarli), Cholbam (cholic acid) capsules, and Chenodal or Ctexli (chenodiol) tablets. Livmarli is an orally administered, minimally-absorbed ileal bile acid transporter (IBAT) inhibitor (IBATi) that is used for the treatment of cholestatic pruritus in patients with Alagille syndrome (ALGS) in the United States and various other countries and for cholestatic pruritus in patient with progressive familial intrahepatic cholestasis (PFIC) in the United States, Canada and Japan. Cholbam is used for the treatment of bile acid synthesis disorders due to single enzyme deficiencies and adjunctive treatment of peroxisomal disorders. The Company is also advancing its product candidate, volixibat, for the treatment of adult patients with cholestatic liver diseases.
Show More

Events Timeline

(ET)
2026-06-14
17:30:00
Mirum and Incyte Announce Phase 2 Results for Zilurgisertib
select
2026-06-04 (ET)
2026-06-04
08:10:00
Mirum and Incyte to Present Zilurgisertib Study Results at ENDO 2026
select
2026-05-31 (ET)
2026-05-31
09:40:00
Mirum Pharmaceuticals Releases New Data on Rare Liver Disease Programs
select
2026-05-12 (ET)
2026-05-12
16:10:00
Mirum Pharmaceuticals Plans to Offer $600M Convertible Senior Notes
select

News

NASDAQ.COM
9.0
06-17NASDAQ.COM
Mirum and Incyte Report Positive Results for FOP Study
  • Clinical Trial Results: Mirum and Incyte's Phase II PROGRESS study of zilurgisertib showed that only 3.1% of patients developed new lesions compared to 16.7% in the placebo group, achieving an 81% reduction, indicating the drug's potential in treating this ultra-rare disease.
  • Sustained Efficacy: In the open-label extension phase, no new lesions were observed among patients continuing zilurgisertib treatment at 48 weeks, with total lesion volume continuing to decline, demonstrating the drug's long-term efficacy and safety, addressing the urgent need for effective treatments.
  • FDA Priority Review: Following positive clinical data, the FDA has accepted the NDA for zilurgisertib and granted Priority Review status, with a decision expected by September 26, 2026, which will expedite the drug's market entry to meet the demand for new therapies.
  • Market Performance: Year-to-date, shares of Mirum and Incyte have risen by 28.5% and 1%, respectively, against a 1.4% decline in the biotech sector, reflecting investor optimism regarding their clinical advancements and enhancing their competitive position in the market.
seekingalpha
9.0
06-15seekingalpha
Mirum and Incyte Report Positive Phase 2 Data for Zilurgisertib
  • Clinical Trial Results: Mirum Pharmaceuticals and Incyte have reported positive pivotal Phase 2 data for their oral FOP candidate, zilurgisertib, with results from Cohort 1 of the PROGRESS study showing consistent treatment effects on disease activity and durability through Week 48, indicating the drug's therapeutic potential.
  • Safety Assessment: During the open-label extension, no new HO lesions were observed in patients continuing zilurgisertib treatment or in placebo patients who crossed over to active treatment at week 24, demonstrating the drug's safety and efficacy in long-term use.
  • FDA Review Progress: The U.S. Food and Drug Administration (FDA) has accepted the New Drug Application for zilurgisertib and granted Priority Review, with a target action date set for September 26, 2026, laying the groundwork for the drug's market launch.
  • Market Outlook: Incyte's Chief Medical Officer Steven Stein stated that the findings represent an important milestone for the zilurgisertib program, further strengthening the clinical evidence supporting its potential as a treatment for FOP, signaling future market opportunities in the rare disease sector.
NASDAQ.COM
9.0
06-15NASDAQ.COM
Mirum and Incyte Announce Positive Phase 2 Results for Zilurgisertib
  • Clinical Trial Results: Mirum and Incyte presented positive results from the PROGRESS study at the 2026 ENDO meeting, showing that Zilurgisertib reduced new heterotopic ossification (HO) lesions by 81% in patients aged 12 and older over 24 weeks, indicating significant efficacy.
  • Efficacy Metrics: Patients treated with Zilurgisertib experienced a 99.9% reduction in the total volume of new HO lesions at week 24, suggesting the drug's high potential in managing Fibrodysplasia Ossificans Progressiva (FOP) and possibly transforming treatment outcomes for patients.
  • Safety Assessment: Zilurgisertib was generally well tolerated during the 24-week placebo-controlled period, with no new HO lesions observed, and total HO lesion volume continued to decrease from week 24 to week 48, indicating potential long-term benefits.
  • Market Outlook: With approximately 300 patients in the U.S. and 900 worldwide affected by FOP, Mirum's NDA for Zilurgisertib is expected to be decided by the FDA in September 2026, which could present significant market opportunities for the company.
Yahoo Finance
8.5
06-14Yahoo Finance
Mirum and Incyte Announce New Progress in FOP Treatment
  • Clinical Trial Results: At the ENDO 2026 conference, Mirum and Incyte presented results from Cohort 1 of the PROGRESS study, showing an 81% reduction in new heterotopic ossification lesions in patients treated with zilurgisertib, indicating significant efficacy in treating FOP.
  • FDA Priority Review: The U.S. FDA has accepted the New Drug Application for zilurgisertib and granted Priority Review, with a decision expected by September 26, 2026, which could provide urgently needed treatment options for FOP patients and potentially reshape the market landscape.
  • Patient Data Analysis: During the 24-week double-blind period, patients receiving zilurgisertib had significantly fewer new lesions compared to the placebo group, and no new lesions were observed during the 48-week open-label extension, demonstrating sustained treatment effects and enhancing the drug's market potential.
  • Safety Assessment: The study indicated that zilurgisertib was well-tolerated during the 24-week controlled period, with most adverse events being mild or moderate and no treatment discontinuations, paving the way for future commercialization and boosting investor confidence.
Newsfilter
9.0
06-14Newsfilter
Mirum and Incyte Announce FOP Study Results
  • Clinical Trial Results: At ENDO 2026, Mirum and Incyte presented data showing that zilurgisertib significantly reduced new HO lesions by 81% in FOP patients over 24 weeks, indicating its potential as a new treatment option for this rare disease.
  • FDA Priority Review: The U.S. FDA has accepted the New Drug Application for zilurgisertib and granted it Priority Review, with a target action date of September 26, 2026, which could expedite its market entry to address urgent patient needs in the FOP community.
  • Study Design and Findings: The PROGRESS study's first cohort included 63 patients, revealing significant reductions in HO lesion volume during the 24-week double-blind period, with no new lesions observed during the open-label extension, suggesting sustained efficacy.
  • Safety Profile: Zilurgisertib demonstrated good tolerability during the 24-week study, with most adverse events being mild or moderate, and no treatment discontinuations, highlighting its safety and feasibility for clinical use.
CNBC
6.0
06-02CNBC
Latest Rating Changes on Wall Street
  • TripAdvisor Upgrade: Wedbush upgraded TripAdvisor from neutral to outperform, citing the stock's undervaluation and expected governance transformation post-LTRIP merger, alongside activist involvement as catalysts for future growth.
  • Knight-Swift Outlook: Susquehanna upgraded Knight-Swift from neutral to positive, highlighting strong earnings prospects in the trucking sector, although it noted that much of the good news is already priced in.
  • Mobia Medical Coverage Initiation: Goldman Sachs initiated coverage on Mobia Medical with a buy rating and a $31 price target, indicating approximately 130% upside potential, reflecting the company's strong growth prospects in the medtech space.
  • Intuit Downgrade: Goldman Sachs downgraded Intuit from neutral to sell, expressing concerns over heightened competition and noting a 46% year-to-date decline in stock price, which raises doubts about its future profitability.
Wall Street analysts forecast MIRM stock price to rise
9 Analyst Rating
Wall Street analysts forecast MIRM stock price to rise
9 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
81.00
Averages
102.33
High
140.00
Current: 0.000
sliders
Low
81.00
Averages
102.33
High
140.00
Citizens
Jonathan Wolleben
Outperform
maintain
$140 -> $146
AI Analysis
2026-06-15
New
Reason
Citizens
Jonathan Wolleben
Price Target
$140 -> $146
AI Analysis
2026-06-15
New
maintain
Outperform
Reason
Citizens analyst Jonathan Wolleben raised the firm's price target on Mirum Pharmaceuticals to $146 from $140 and keeps an Outperform rating on the shares. Mirum's acquisition of zilurgisertib increasingly looks like a potentially attractive late-stage deal, as newly disclosed data suggest meaningful clinical benefit in fibrodysplasia ossificans progressiva despite the Phase 2b trial missing its primary endpoint, supporting approval potential, a meaningful commercial opportunity, and a fit with the company's existing infrastructure that could make the asset accretive relatively quickly, the analyst tells investors in a research note.
Morgan Stanley
NULL
to
Overweight
maintain
$140 -> $150
2026-06-11
Reason
Morgan Stanley
Price Target
$140 -> $150
2026-06-11
maintain
NULL
to
Overweight
Reason
Morgan Stanley raised the firm's price target on Mirum Pharmaceuticals (MIRM) to $150 from $140 and keeps an Overweight rating on the shares. Hepatitis delta virus remains underdiagnosed and recent U.S. approval of bulevirtide sets the stage for market expansion, says the analyst, who believes the next wave of therapies from Vir Biotechnology (VIR) and Mirum represent notable improvements and are "best positioned to benefit in this currently underappreciated market."
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for MIRM
Unlock Now

Valuation Metrics

The current forward P/E ratio for Mirum Pharmaceuticals Inc (MIRM.O) is 2000.00, compared to its 5-year average forward P/E of 167.29. For a more detailed relative valuation and DCF analysis to assess Mirum Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
167.29
Current PE
2000.00
Overvalued PE
773.00
Undervalued PE
-438.41

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
1201.93
Current EV/EBITDA
-22.01
Overvalued EV/EBITDA
10410.13
Undervalued EV/EBITDA
-8006.26

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
6.27
Current PS
8.02
Overvalued PS
8.74
Undervalued PS
3.80

Financials

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Whales Holding MIRM

E
Eventide Asset Management, LLC
Holding
MIRM
+30.67%
3M Return
E
Emerald Advisers, LLC
Holding
MIRM
+28.58%
3M Return
H
Hennion & Walsh Asset Management, Inc.
Holding
MIRM
+20.68%
3M Return
R
Rock Springs Capital Management LP
Holding
MIRM
+18.31%
3M Return
N
Novo Holdings A/S
Holding
MIRM
+17.23%
3M Return
B
BVF Partners L.P.
Holding
MIRM
+14.24%
3M Return

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Frequently Asked Questions

What is Mirum Pharmaceuticals Inc (MIRM) stock price today?

The current price of MIRM is 107.13 USD — it has increased 4.99

What is Mirum Pharmaceuticals Inc (MIRM)'s business?

Mirum Pharmaceuticals, Inc. is a biopharmaceutical company. The Company is focused on the treatment of rare diseases affecting children and adults. It has three medicines: LIVMARLI (maralixibat) oral solution (Livmarli), Cholbam (cholic acid) capsules, and Chenodal or Ctexli (chenodiol) tablets. Livmarli is an orally administered, minimally-absorbed ileal bile acid transporter (IBAT) inhibitor (IBATi) that is used for the treatment of cholestatic pruritus in patients with Alagille syndrome (ALGS) in the United States and various other countries and for cholestatic pruritus in patient with progressive familial intrahepatic cholestasis (PFIC) in the United States, Canada and Japan. Cholbam is used for the treatment of bile acid synthesis disorders due to single enzyme deficiencies and adjunctive treatment of peroxisomal disorders. The Company is also advancing its product candidate, volixibat, for the treatment of adult patients with cholestatic liver diseases.

What is the price predicton of MIRM Stock?

Wall Street analysts forecast MIRM stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for MIRM is102.33 USD with a low forecast of 81.00 USD and a high forecast of 140.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Mirum Pharmaceuticals Inc (MIRM)'s revenue for the last quarter?

Mirum Pharmaceuticals Inc revenue for the last quarter amounts to 159.88M USD, increased 43.28

What is Mirum Pharmaceuticals Inc (MIRM)'s earnings per share (EPS) for the last quarter?

Mirum Pharmaceuticals Inc. EPS for the last quarter amounts to -13.43 USD, increased 4376.67

How many employees does Mirum Pharmaceuticals Inc (MIRM). have?

Mirum Pharmaceuticals Inc (MIRM) has 369 emplpoyees as of June 20 2026.

What is Mirum Pharmaceuticals Inc (MIRM) market cap?

Today MIRM has the market capitalization of 6.53B USD.