MeiraGTx Signs Exclusive License Agreement with ZipBio
MeiraGTx signed an exclusive license agreement with ZipBio, a biotechnology company pioneering AI-driven protein therapeutics. Under the agreement, MeiraGTx will receive exclusive rights to ZipBio's first-in-class therapies for Geographic Atrophy, targeting the complement pathway. The licensing deal combines MeiraGTx's vector design, clinical development, and in-house manufacturing of genetic medicines, and ZipBio's de novo-designed protein therapeutics, developed using its COMPACT generative AI platform. The agreement includes upfront, as well as potential milestone and royalty payments. Financial terms were not disclosed. COMPACT is ZipBio's proprietary generative AI platform for designing protein therapeutics beyond the limits of conventional biologics.
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Eli Lilly Enhances Genetic Eye Disease Pipeline Through Collaboration with MeiraGTx on Gene Therapy
MeiraGTx and Eli Lilly Collaboration: MeiraGTx Holdings has entered a strategic partnership with Eli Lilly, granting exclusive rights to its AAV-AIPL1 program for treating Leber congenital amaurosis 4, with an upfront payment of $75 million and potential milestone payments exceeding $400 million.
Clinical Success of AAV-AIPL1: Clinical trials showed that all 11 children treated with AAV-AIPL1 gained vision, with additional improvements in communication, behavior, learning, and social integration.
Riboswitch Technology: The collaboration includes access to MeiraGTx’s riboswitch technology for gene editing in ophthalmology, allowing precise control over therapeutic protein production through oral dosing.
SanegeneBio and Eli Lilly Partnership: SanegeneBio has also partnered with Eli Lilly to advance RNAi candidates for metabolic diseases, with potential milestone payments up to $1.2 billion and a focus on developing therapies that can be administered infrequently.
Eli Lilly Partners with MeiraGTx to Create Gene Therapies for Ocular Disorders
Collaboration Announcement: MeiraGTx (MGTX) shares rose approximately 18% in premarket trading after announcing a strategic collaboration with Eli Lilly (LLY) to develop gene therapies for eye diseases, specifically targeting Leber congenital amaurosis 4 (LCA4).
Exclusive Rights and Financial Terms: Under the agreement, Eli Lilly will receive exclusive global rights to MGTX's AAV-AIPL1 gene therapy program and other gene therapy technologies, with MeiraGTx set to receive $75 million upfront and over $400 million based on milestone achievements, along with tiered royalties on future sales.
Raymond James Begins Coverage of MeiraGTx Holdings with Strong Buy Rating and Sets Price Target at $29
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Community Engagement: Over 10,000 serious traders are part of the Benzinga Pro community, indicating a robust network for sharing market intelligence.
Market Winning Tools: Benzinga Pro is designed to equip traders with the tools and information necessary to succeed in the markets daily.
Insider Sale: CFO & COO of $MGTX Sells 24,000 Shares
Insider Trading Activity: Richard Giroux, CFO & COO of $MGTX, sold 24,000 shares for approximately $204,480, marking a 2.7% reduction in his holdings, with no insider purchases reported in the last six months.
Analyst Ratings and Institutional Activity: Recent reports show that 59 institutional investors increased their stakes in $MGTX, while analysts have issued two buy ratings and set a median price target of $24.0 for the stock.
Coinbase To Rally Around 17%? Here Are 10 Top Analyst Forecasts For Wednesday
Analyst Rating Changes: Various Wall Street analysts have adjusted their price targets for several companies, with notable changes including HC Wainwright lowering Annexon, Inc.'s target from $20 to $14 while maintaining a Buy rating, and Rosenblatt increasing Coinbase Global, Inc.'s target from $260 to $300, also keeping a Buy rating.
Stock Performance Insights: Other companies such as V.F. Corporation and Camtek Ltd saw their price targets cut, while Wingstop Inc. and Danaos Corporation had their targets raised, reflecting mixed sentiments in the market regarding these stocks.
Chardan Capital Maintains Buy on MeiraGTx Hldgs, Lowers Price Target to $35
Real-time Intelligence for Traders: Benzinga Pro offers the fastest news alerts and exclusive stories to help traders make informed decisions in the stock market.
Community of Serious Traders: Over 10,000 traders are part of the Benzinga Pro community, benefiting from accurate market intelligence and insights.
Eli Lilly Enhances Genetic Eye Disease Pipeline Through Collaboration with MeiraGTx on Gene Therapy
MeiraGTx and Eli Lilly Collaboration: MeiraGTx Holdings has entered a strategic partnership with Eli Lilly, granting exclusive rights to its AAV-AIPL1 program for treating Leber congenital amaurosis 4, with an upfront payment of $75 million and potential milestone payments exceeding $400 million.
Clinical Success of AAV-AIPL1: Clinical trials showed that all 11 children treated with AAV-AIPL1 gained vision, with additional improvements in communication, behavior, learning, and social integration.
Riboswitch Technology: The collaboration includes access to MeiraGTx’s riboswitch technology for gene editing in ophthalmology, allowing precise control over therapeutic protein production through oral dosing.
SanegeneBio and Eli Lilly Partnership: SanegeneBio has also partnered with Eli Lilly to advance RNAi candidates for metabolic diseases, with potential milestone payments up to $1.2 billion and a focus on developing therapies that can be administered infrequently.
Eli Lilly Partners with MeiraGTx to Create Gene Therapies for Ocular Disorders
Collaboration Announcement: MeiraGTx (MGTX) shares rose approximately 18% in premarket trading after announcing a strategic collaboration with Eli Lilly (LLY) to develop gene therapies for eye diseases, specifically targeting Leber congenital amaurosis 4 (LCA4).
Exclusive Rights and Financial Terms: Under the agreement, Eli Lilly will receive exclusive global rights to MGTX's AAV-AIPL1 gene therapy program and other gene therapy technologies, with MeiraGTx set to receive $75 million upfront and over $400 million based on milestone achievements, along with tiered royalties on future sales.
Raymond James Begins Coverage of MeiraGTx Holdings with Strong Buy Rating and Sets Price Target at $29
Real-time Intelligence: Benzinga Pro offers the fastest news alerts for traders, helping them stay informed and make timely decisions in the stock market.
Exclusive Content: The platform provides exclusive stories and insights generated by Benzinga reporters, enhancing the trading experience for its users.
Community Engagement: Over 10,000 serious traders are part of the Benzinga Pro community, indicating a robust network for sharing market intelligence.
Market Winning Tools: Benzinga Pro is designed to equip traders with the tools and information necessary to succeed in the markets daily.
Insider Sale: CFO & COO of $MGTX Sells 24,000 Shares
Insider Trading Activity: Richard Giroux, CFO & COO of $MGTX, sold 24,000 shares for approximately $204,480, marking a 2.7% reduction in his holdings, with no insider purchases reported in the last six months.
Analyst Ratings and Institutional Activity: Recent reports show that 59 institutional investors increased their stakes in $MGTX, while analysts have issued two buy ratings and set a median price target of $24.0 for the stock.
Coinbase To Rally Around 17%? Here Are 10 Top Analyst Forecasts For Wednesday
Analyst Rating Changes: Various Wall Street analysts have adjusted their price targets for several companies, with notable changes including HC Wainwright lowering Annexon, Inc.'s target from $20 to $14 while maintaining a Buy rating, and Rosenblatt increasing Coinbase Global, Inc.'s target from $260 to $300, also keeping a Buy rating.
Stock Performance Insights: Other companies such as V.F. Corporation and Camtek Ltd saw their price targets cut, while Wingstop Inc. and Danaos Corporation had their targets raised, reflecting mixed sentiments in the market regarding these stocks.
Chardan Capital Maintains Buy on MeiraGTx Hldgs, Lowers Price Target to $35
Real-time Intelligence for Traders: Benzinga Pro offers the fastest news alerts and exclusive stories to help traders make informed decisions in the stock market.
Community of Serious Traders: Over 10,000 traders are part of the Benzinga Pro community, benefiting from accurate market intelligence and insights.
