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MGTX Overview

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ET
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ET
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Intellectia

Loading chart...

High
10.320
Open
9.870
VWAP
10.04
Vol
1.88M
Mkt Cap
916.27M
Low
9.600
Amount
18.88M
EV/EBITDA(TTM)
--
Total Shares
81.45M
EV
780.81M
EV/OCF(TTM)
--
P/S(TTM)
9.37
MeiraGTx Holdings PLC is a vertically integrated, clinical-stage genetic medicines company. It has a pipeline of late-stage clinical programs, including Parkinson’s disease, radiation-induced xerostomia and AIPL1-associated retinal dystrophy. It is focused on vivo delivery of vectorized biologic therapeutics addressing unmet needs in prevalent disorders, including severe forms of xerostomia, neurodegenerative diseases and ocular diseases, including inherited retinal diseases (IRDs), and large degenerative ocular diseases. The Company’s product pipeline includes Botaretigene Sparoparvovec for the treatment of X-linked Retinitis Pigmentosa; AAV-hAQP1 for the treatment of Radiation-Induced Grade 2/3 Xerostomia; AAV-hAQP1 for the treatment of Sjogren’s Syndrome; AAV-GAD for the treatment of Parkinson’s Disease; AAV-RPE65 for the treatment of RPE65-Associated Retinal Dystrophy; AAV-CNGB3 and AAV-CNGA3 for the treatment of Achromatopsia; AAV-AIPL1 for the treatment of LCA4, and others.
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Events Timeline

(ET)
2026-04-16
07:30:00
MeiraGTx Releases Three-Year Data on AAV-hAQP1
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2026-04-16
07:30:00
MeiraGTx Acquires bota-vec from Johnson & Johnson
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2026-03-26 (ET)
2026-03-26
08:20:00
MeiraGTx Awarded Breakthrough Designation for AAV2-hAQP1
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2026-03-08 (ET)
2026-03-08
22:30:00
KKR Plans to Sell CoolIT Systems for Over $3B
select
2026-03-08
17:00:00
Dr. Vinay Prasad to Leave Agency at End of April
select
link

News

Newsfilter
8.5
04-16Newsfilter
PinnedMeiraGTx Acquires bota-vec from J&J for XLRP Treatment
  • Asset Purchase Agreement: MeiraGTx has entered into an agreement with Johnson & Johnson to acquire bota-vec for $25 million, significantly enhancing its market position in the treatment of X-linked retinitis pigmentosa (XLRP).
  • Global Regulatory Filings: The company intends to immediately pursue global regulatory filings for bota-vec, aiming for a potential launch in 2027, addressing the urgent treatment needs of over 20,000 XLRP patients, which presents substantial market potential.
  • Clinical Trial Data Support: The LUMEOS Phase 3 study demonstrated significant improvements in low luminance visual acuity with bota-vec, with many patients reporting real-world benefits, providing strong support for regulatory approval.
  • Strategic Development Goals: By reacquiring bota-vec, MeiraGTx not only strengthens its product pipeline but also plans to launch two products targeting severe unmet needs within the next two years, further solidifying its leadership in the gene therapy sector.
seekingalpha
8.5
04-16seekingalpha
MeiraGTx Prices $100M Equity Offering to Acquire Gene Therapy bota-vec
  • Equity Offering: MeiraGTx Holdings (MGTX) plans to raise nearly $100 million by pricing an offering of approximately 11.1 million shares at $9.00 each, reflecting the company's confidence in funding the market launch of its gene therapy bota-vec.
  • Asset Purchase Agreement: The company has entered into an asset purchase agreement with Johnson & Johnson (JNJ) to acquire bota-vec related to X-linked retinitis pigmentosa, with JNJ receiving $25 million upfront and a milestone payment tied to U.S. approval and sales performance, indicating JNJ's commitment to the product.
  • Future Royalties: Under the agreement, beginning mid-2029, JNJ will receive high double-digit royalties based on worldwide net sales of bota-vec, which could provide long-term revenue support for MeiraGTx while underscoring JNJ's confidence in the product's market potential.
  • Regulatory Submission Plans: MeiraGTx stated it will immediately file global regulatory submissions for bota-vec approval, with a commercial launch expected in H2 2028, demonstrating the company's strategic positioning and intent to expand in the gene therapy market.
seekingalpha
8.5
04-14seekingalpha
MeiraGTx Shares Surge 17% to 52-Week High Ahead of Gene Therapy Data Presentation
  • Clinical Trial Data Disclosure: MeiraGTx is set to present early-stage trial data for its AAV-hAQP1 gene therapy on April 16 at 8:00 AM ET, showcasing three-year data from a Phase 1 trial, which could significantly boost investor confidence in the company's future prospects.
  • Market Opportunity Analysis: This one-time therapy targets radiation-induced xerostomia, a long-term side effect affecting head and neck cancer patients, indicating a substantial market demand, and successful commercialization could yield significant revenue for the company.
  • Clinical Study Context: The open-label AQUAx clinical study evaluated AAV-hAQP1 in patients with grade 2/3 moderate to severe radiation-induced xerostomia who have been cancer-free for at least five years post-radiation therapy, highlighting the therapy's potential efficacy.
  • Interactive Session Arrangement: The webcast will include the disclosure of long-term data and a discussion on the drug's commercial opportunities, followed by a Q&A session, enhancing engagement with investors and fostering transparency and trust.
Newsfilter
9.0
04-14Newsfilter
MeiraGTx Presents 3-Year Data from AQUAx Clinical Study
  • Clinical Data Presentation: MeiraGTx will present three-year follow-up data from the AAV-hAQP1 treatment for radiation-induced xerostomia during a conference call on April 16, 2026, which is expected to enhance investor confidence in the company's R&D capabilities.
  • Study Design Overview: The Phase 1 AQUAx clinical trial is an open-label, non-randomized, dose-escalation study primarily assessing the safety of AAV-hAQP1, with efficacy endpoints including patient-reported xerostomia symptoms and changes in parotid gland saliva flow, showcasing the company's innovative potential in gene therapy.
  • Patient Follow-Up Plan: Participants will be followed for five years after a one-time administration of AAV-hAQP1, ensuring the long-term validity and reliability of the data, which provides a solid foundation for future clinical applications.
  • Commercial Opportunity Discussion: The meeting will include discussions on disease burden, patient experience, and treatment administration, emphasizing MeiraGTx's market potential in addressing radiation-induced xerostomia, which may attract more investor interest in its commercialization prospects.
NASDAQ.COM
9.5
03-26NASDAQ.COM
MeiraGTx Stock Rises After Financial Results Announcement
  • Improved Financial Performance: MeiraGTx Holdings plc reported its full-year 2025 financial results, showing a narrower loss of $114.2 million or $1.42 per share, down from $147.8 million or $2.12 per share last year, indicating progress in cost control and operational efficiency.
  • FDA Breakthrough Designation: The company received FDA's Breakthrough Designation for its AAV2-hAQP1 treatment targeting Grade 2 and Grade 3 xerostomia caused by radiotherapy, which will expedite product development and potentially enhance market competitiveness, attracting more investor interest.
  • Stock Price Movement: Currently, MeiraGTx's stock is trading at $8.04, up 5.51% from the opening price of $7.69, reaching a high of $8.54 during today's session, reflecting optimistic market sentiment regarding the company's prospects.
  • Annual Trading Range: Over the past year, MeiraGTx's stock has fluctuated between $4.55 and $9.73, indicating market uncertainty about its business developments, but recent financial improvements may bolster investor confidence.
Newsfilter
9.0
03-26Newsfilter
MeiraGTx Receives FDA Breakthrough Therapy Designation for AAV2-hAQP1
  • Breakthrough Therapy Designation: MeiraGTx's AAV2-hAQP1 treatment has received FDA Breakthrough Therapy Designation for Grade 2 and 3 xerostomia caused by radiotherapy, marking a significant advancement in cancer treatment and enhancing the company's competitive position in the market.
  • Strategic Partnership: The collaboration with Eli Lilly provides MeiraGTx with a $75 million upfront payment and potential milestone payments exceeding $400 million, significantly bolstering the company's financial stability and research capabilities.
  • Clinical Trial Progress: MeiraGTx plans to update on the long-term data for the AAV2-hAQP1 program on April 16, 2026, which is expected to support a potential Biologics License Application (BLA) submission in the first half of 2027, with a target launch in the U.S. in early 2028.
  • AI Technology Application: The collaboration with Hologen applies AI technology to clinical data analysis, de-risking the AAV-GAD program and identifying treatment effects on Parkinson's disease physiology, with plans to initiate a pivotal Phase 3 clinical trial in the coming months.
Wall Street analysts forecast MGTX stock price to rise
6 Analyst Rating
Wall Street analysts forecast MGTX stock price to rise
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
14.00
Averages
21.50
High
30.00
Current: 0.000
sliders
Low
14.00
Averages
21.50
High
30.00
RBC Capital
Outperform
maintain
$16 -> $24
AI Analysis
2026-04-17
New
Reason
RBC Capital
Price Target
$16 -> $24
AI Analysis
2026-04-17
New
maintain
Outperform
Reason
RBC Capital raised the firm's price target on MeiraGTx to $24 from $16 and keeps an Outperform rating on the shares. The company's 3-year follow-up data from the Phase I xerostomia program shows "promising durability", and the firm is positive that XLRP program is back under MeiraGTx control as they intend to file imminently and potentially launch in 2027, the analyst tells investors in a research note.
Evercore ISI
Gavin Clark-Gartner
Outperform
downgrade
$20 -> $18
2026-04-01
Reason
Evercore ISI
Gavin Clark-Gartner
Price Target
$20 -> $18
2026-04-01
downgrade
Outperform
Reason
Evercore ISI analyst Gavin Clark-Gartner lowered the firm's price target on MeiraGTx to $18 from $20 and keeps an Outperform rating on the shares. The firm adjusted targets for its small-to-mid cap biotechnology coverage as it analyzed Q2 catalysts. However, the firm acknowledges that stocks in the group are moving on longer-horizon theses so it also looked at all FY26 catalysts, the analyst tells investors.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for MGTX
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Valuation Metrics

The current forward P/E ratio for MeiraGTx Holdings PLC (MGTX.O) is 1.61, compared to its 5-year average forward P/E of -10.91. For a more detailed relative valuation and DCF analysis to assess MeiraGTx Holdings PLC's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-10.91
Current PE
1.61
Overvalued PE
21.86
Undervalued PE
-43.68

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
4.29
Current EV/EBITDA
11.69
Overvalued EV/EBITDA
35.42
Undervalued EV/EBITDA
-26.83

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
24.38
Current PS
6.24
Overvalued PS
48.31
Undervalued PS
0.46

Financials

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Whales Holding MGTX

P
Perceptive Advisors LLC
Holding
MGTX
+12.83%
3M Return
R
Rubric Capital Management LP
Holding
MGTX
+3.33%
3M Return

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Frequently Asked Questions

What is MeiraGTx Holdings PLC (MGTX) stock price today?

The current price of MGTX is 10.19 USD — it has increased 7.49

What is MeiraGTx Holdings PLC (MGTX)'s business?

MeiraGTx Holdings PLC is a vertically integrated, clinical-stage genetic medicines company. It has a pipeline of late-stage clinical programs, including Parkinson’s disease, radiation-induced xerostomia and AIPL1-associated retinal dystrophy. It is focused on vivo delivery of vectorized biologic therapeutics addressing unmet needs in prevalent disorders, including severe forms of xerostomia, neurodegenerative diseases and ocular diseases, including inherited retinal diseases (IRDs), and large degenerative ocular diseases. The Company’s product pipeline includes Botaretigene Sparoparvovec for the treatment of X-linked Retinitis Pigmentosa; AAV-hAQP1 for the treatment of Radiation-Induced Grade 2/3 Xerostomia; AAV-hAQP1 for the treatment of Sjogren’s Syndrome; AAV-GAD for the treatment of Parkinson’s Disease; AAV-RPE65 for the treatment of RPE65-Associated Retinal Dystrophy; AAV-CNGB3 and AAV-CNGA3 for the treatment of Achromatopsia; AAV-AIPL1 for the treatment of LCA4, and others.

What is the price predicton of MGTX Stock?

Wall Street analysts forecast MGTX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for MGTX is21.50 USD with a low forecast of 14.00 USD and a high forecast of 30.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is MeiraGTx Holdings PLC (MGTX)'s revenue for the last quarter?

MeiraGTx Holdings PLC revenue for the last quarter amounts to 75.36M USD, increased 252.33

What is MeiraGTx Holdings PLC (MGTX)'s earnings per share (EPS) for the last quarter?

MeiraGTx Holdings PLC. EPS for the last quarter amounts to 0.19 USD, decreased -138.00

How many employees does MeiraGTx Holdings PLC (MGTX). have?

MeiraGTx Holdings PLC (MGTX) has 400 emplpoyees as of April 17 2026.

What is MeiraGTx Holdings PLC (MGTX) market cap?

Today MGTX has the market capitalization of 916.27M USD.