Linde Analyst Starts Coverage Optimistically; Check Out the Top 5 Initiations for Wednesday
Analyst Coverage Initiations: Several Wall Street analysts have initiated coverage on various companies, providing Buy and Outperform ratings along with price targets.
Traws Pharma, Inc.: HC Wainwright & Co. analyst Brandon Folkes initiated coverage with a Buy rating and a price target of $8, while shares closed at $2.16.
Compass Therapeutics, Inc.: Canaccord Genuity analyst John Newman also initiated coverage with a Buy rating and a price target of $10, with shares closing at $5.22.
Linde plc and Others: CICC analyst Shanshan Shen rated Linde plc as Outperform with a price target of $510, and HC Wainwright initiated coverage on Pelthos Therapeutics and LifeSci Capital on Oculis Holding, both with positive ratings and significant price targets.
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Oculis Receives FDA Breakthrough Therapy Designation, Potential Market Exceeds $7 Billion
- Breakthrough Therapy Designation: Oculis's Privosegtor has received FDA breakthrough therapy designation due to significant vision improvements in the ACUITY Phase 2 trial, positioning it as the first neuroprotective therapy for optic neuropathies, addressing a critical unmet medical need.
- Substantial Market Potential: The PIONEER program aims to support registration for Privosegtor in optic neuritis and non-arteritic anterior ischemic optic neuropathy, representing a potential market opportunity exceeding $7 billion, highlighting the company's strategic focus in neuro-ophthalmology.
- Clinical Trial Progress: Oculis's OCS-01 eye drops are currently in Phase 3 trials, with topline results from the DIAMOND trial expected in Q2 2026, and if approved, it will be the first non-invasive treatment for diabetic macular edema.
- Future Outlook: CEO Riad Sherif stated that 2026 is set to be a milestone-rich year for Oculis, with advancements in both Privosegtor and OCS-01 expected to significantly transform the treatment landscape for neuro-axonal diseases.

Oculis Receives FDA Breakthrough Therapy Designation, Potential Market Exceeds $7 Billion
- Breakthrough Therapy Designation: Oculis's Privosegtor has received FDA breakthrough therapy designation based on significant vision improvement shown in the ACUITY Phase 2 trial, potentially becoming the first neuroprotective therapy for optic neuritis, addressing a substantial unmet medical need.
- Significant Market Opportunity: The PIONEER program by Oculis includes three pivotal trials for optic neuritis and non-arteritic anterior ischemic optic neuropathy (NAION), with a projected market opportunity exceeding $7 billion in the U.S., showcasing the company's strategic positioning in neuro-ophthalmology.
- Clinical Trial Progress: OCS-01 eye drops are currently in Phase 3 development targeting diabetic macular edema (DME), with topline results from the DIAMOND Phase 3 trials expected in Q2 2026, which could fill a significant market gap if approved.
- Industry Conference Presentation: Oculis CEO Riad Sherif will present at the J.P. Morgan Healthcare Conference on January 14, 2026, highlighting the company's innovative potential and market prospects in the neuro-ophthalmology sector.









